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Sanorin 0.05% 10 ml nasal drops


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The instruction for medical use

of SANORIN medicine

the Trade name

the International unlicensed

name Naphazoline Dosage Form
of the Drop in a nose of 0.1%, 0.05%

of 1 ml of solution contains
active agent – naphazoline nitrate of 0.001 g, 0.0005 g
excipients: boric acid, ethylene diamine, methylparaben, the water purified.

flavourless Colourless transparent solution

Pharmacotherapeutic group
Nasal drugs. Antikongestanta and other nasal drugs for topical administration. Sympathomimetics. Naphazoline.
The ATX R01AA08 code

the Pharmacological

Pharmacokinetics At properties topical administration vasoconstrictive effect occurs in 5-10 minutes and proceeds from 2 to 6 hours. It is absorbed in a system blood stream and can have systemic action.
The pharmacodynamics
Sanorin contains the naphazoline which is the system sympathomimetic operating on alpha adrenoceptors. Renders expressed and the continuing vasoconstrictive action on vessels of mucous membranes is long. At intranasal use, naphazoline narrows vessels, reduces exudation, facilitating, thus, nasal breath and reducing puffiness mucous at inflammations of upper airways.

– acute rhinitis
– sinusitis
– inflammation of Eustachian tubes
– inflammation of a middle ear
– for removal of a rhinedema at diagnostic and therapeutic interventions

the Route of administration and doses
Solution of 0.1%
to Adults and teenagers are more senior than 15 years – on 1-3 drops of solution in each nasal course, put 2-3 times, with an interval not less than 4 hours.
To apply 5-6 days.
Solution of 0.05%
to Children from 3 to 6 years – 1-2 drops of 0.05% of solution
to Children from 6 to 15 years – on 2 drops of 0.05% of solution
2-3 times a day, with an interval not less than 4 hours.
To apply no more than 3 days.
In case of bleeding from a front part of a nose, it is possible to insert the tampon moistened in 0.05% Sanorin solution.
For the diagnostic purposes before nasal endoscopy (for example, for diagnostics and treatment of polyps of a nose), dig in 3 – 4 drops of drug in each nostril after cleaning of a nose or insert the tampon moistened in solution Sanorin of 0.05% for 1 – 2 minutes.
Drug is dug in in each nostril, the head has to be inclined back. During instillation in the left nostril it is reasonable to turn slightly the head to the left, at instillation in the right nostril, to turn the head to the right.

Side effects
At use in the recommended doses drug usually well is transferred.
– nausea, a headache, nervousness, a tremor
– tachycardia, increase in arterial blood pressure, heartbeat
– a reactive hyperemia, the increased sweating
– burning sensation or dryness in a nose
– hypostasis of a mucous membrane of a nasal cavity (at use more than 7 days)
– atrophic rhinitis
Very seldom:
– the intensive congestion of a nose, after weakening of effect of drug
can result Too frequent use in the dependence accompanied with the intensive hypostasis of a mucous membrane occurring during rather short time after use. Prolonged use of drug can lead to disturbance of an epithelium of a mucous membrane, inhibition of tsiliarny activity and to lead to irreversible injury of a mucous membrane and development of dry rhinitis.

– hypersensitivity to active agents or to auxiliary components of drug
– dry rhinitis
– children’s age up to 3 years for 0.05% of solution
– children’s age up to 15 years for 0.1% of solution
– diabetes
– the profound atherosclerosis
– a thyrotoxicosis

Medicinal interactions
it is not necessary to use Drug along with monoaminooxidase inhibitors, tricyclic antidepressants and Maprotilinum as there can be a disturbance of a warm rhythm and increase in arterial blood pressure.

It is necessary to appoint the special instructions Drug carefully in diseases of a cardiovascular system (hypertension, coronary heart disease), a pheochromocytoma or with potentially hypertensive drugs.
At prolonged use the expressiveness of vasoconstrictive action gradually decreases (the tachyphylaxis phenomenon), in communication with what no more than 5 days are recommended to use drug.
It is necessary to be careful during the general anesthesia by means of anesthetics which increase sensitivity of a myocardium to sympathomimetics (for example, a halothane), at patients with bronchial asthma.
It is necessary to avoid prolonged use and overdose. Prolonged use of the medicines intended for removal of hypostasis of a mucous membrane can lead to hypostasis and the subsequent mucosal atrophy of a nose.
This medicine contains methylparaben which can cause allergic reactions (perhaps, the slowed-down type).
Pregnancy and the period of a lactation
are Not enough information on ability of naphazoline to get through a placenta and to be allocated in breast milk. Therefore pregnant women or the feeding women need to consider potential risks and advantages of treatment before administration of drug, to appoint drug, only in case of emergency.
Features of influence of medicine on ability to run the vehicle or potentially dangerous mechanisms.
Drug does not affect ability to run motor transport or potentially dangerous mechanisms.

Symptoms: the headache, a tremor, tachycardia, heartbeat or a hypertension can lead accidental consumption of drug to emergence of system undesirable reactions, such as nervousness, the increased sweating. Possible symptoms of overdose are provided by nausea, cyanosis, fever, spasms, cardiac arrest, a fluid lungs and respiratory or psychiatric problems. Besides, it is possible to notice the oppression of the central nervous system accompanied with drowsiness, decrease in body temperature, bradycardia, sweating, shocklike hypotension, an apnoea or a coma.
Treatment: symptomatic.
The risk of overdose is higher at children as they are more susceptible to adverse effects, than adults.

A form of release and packing
On 10 ml in the bottle of brown glass supplied with a dropper with a cover from polyethylene with control of the first opening. Each bottle supplied with the label together with the instruction for medical use in the state and Russian languages is put in a box of cardboard.

To Store storage conditions in the place protected from light, at a temperature from 10 s to +25C.
To protect from freezing.
To store out of children’s reach!

A period of storage
3 years for drops of 0.05%. 4 years for drops of 0.1%.
Not to apply after an expiration date.

Prescription status
Without prescription

the Producer
Teva Czech Industries s.r.o., the Czech Republic
Teva the Czech Enterprises of neuter of the lake, the Czech Republic

the Name and the country of the owner of the registration certificate
of Teva Pharmaceutical Industries Ltd, Israel
Teva Pharmatsevticheskiye Predpriyatiya Ltd, Israel
the Address of the organization accepting in the territory of the Republic of Kazakhstan claims from consumers on quality of products (goods): Ratiopharm Kazakhstan LLP 050000 Republic Kazakhstang. Almaty, Al-Farabi Avenue 19, Nurla Tau’s Business center of 1 B, office of 603 Phone number, fax: (727) 311-09-15, 311-07-34 E-mail:

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