Antibacterial and Anti-Inflammatory / Eye Care

Levoksimed 5 ml of 0.5% eye drops

Brands: WORLD MEDICINE (Turkey)

$19.00

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Levoksimed 5 ml of 0.5% eye drops quantity

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660b9f68bfd4

Brands:: WORLD MEDICINE (Turkey)

Description

The instruction for medical use of LEFT XYHONEY medicine the Trade name Left xyhoney the International unlicensed name Levofloxacin Dosage Form of the Drop eye 0.5% Structure of 1 ml of drug contains active agent – levofloxacin (in the form of a levofloksatsin of the gemigidrat) 5 mg, excipients: sodium chloride, a benzalkoniya chloride, sodium hydroxide or Acidum hydrochloricum, water for injections. The description Transparent light yellow or chartreuse solution Pharmacotherapeutic group Drugs for treatment of diseases of eyes. Antimicrobial drugs others. Levofloxacin. The ATX S01AX19 code the Pharmacological Pharmacokinetics Later properties of instillation in an eye levofloxacin well remains in a plaintive film. In researches on healthy volunteers it was shown that the average concentration of a levofloksatsin in a plaintive film measured in 4 and 6 hours after topical administration made 17.0 mkg/ml and 6.6 mkg/ml respectively. At five of six examinees of concentration of a levofloksatsin made 2 mkg/ml and above in 4 hours after instillation. At four of six examinees this concentration remained in 6 hours after instillation. Average concentration of a levofloksatsin was measured in blood plasma at 15 healthy adult volunteers at use of eye/ear drops of a levofloksatsin within 15 days. Average concentration of a levofloksatsin in plasma in 1 hour after use made from 0.86 ng/ml in the 1st day up to 2.05 ng/ml for the 15th day. The maximum concentration of a levofloksatsin in plasma, equal 2.25 ng/ml, is revealed for the 4th day after two days of use of drug each 2 hours up to 8 times a day. The maximum concentration of a levofloksatsin reached for the 15th day was more than 1000 times lower than concentration which is noted after oral administration of standard doses of a levofloksatsin. A pharmacodynamics Left xyhoney – antimicrobial drug from group of ftorkhinolon. Levofloxacin – L-isomer of racemic medicinal substance of an ofloksatsin. The antibacterial activity of an ofloksatsin belongs, mainly, to L-isomer. Levofloxacin blocks DNK-girazu and topoisomerase IV, breaks superspiralling and a stitching of ruptures of DNA, suppresses DNA synthesis, causes profound morphological changes in cytoplasm, a cell wall and membranes of bacteria. It is effective concerning the following microorganisms: Category I: The most susceptible types Aerobic gram-positive: Staphylococcus aureus (MSSA) * Streptococcus pneumoniae Streptococcus pyogenes Viridans group streptococci Aerobic Gram-negative: Escherichia coli Haemophilus influenzae Moraxella catarrhalis Pseudomonas aeruginosa (local cultures) Other microorganisms of Chlamydia trachomatis (treatment of patients with chlamydial conjunctivitis demands the accompanying system antimicrobic therapy) Category II: Types for which the acquired stability can be a problem of Aerobic Gram-positive micro-organisms Staphylococcus aureus (MRSA) ** Staphylococcus epidermidis Aerobic Gram-negative micro-organisms Pseudomonas aeruginosa (Hospital isolates) * MSSA = Methicillinum – sensitive strains of Staphylococcus aureus ** MRSA = Methicillinum – resistant strains of Staphylococcus aureus Indications treatment of superficial bacterial infections of an eye at patients aged from 1 year and are more senior prevention of complications after surgical and laser eye surgeries the Route of administration and doses Only for topical administration. Adults and children aged from 1 year are also more senior Within the first 2 days instillirut 1-2 drops of solution in one struck eyes each 2 hours, up to 8 times a day. Within 3-5 days each 4 hours (up to 4 times a day). Duration of treatment depends on disease severity and development of clinical and bacteriological infection, is usually 5 days. At simultaneous use of several ophthalmologic drugs for topical administration it is necessary to observe a 15-minute interval between instillations. In order to avoid solution pollution it is not necessary to touch with a tip of a dropper by centuries and fabrics around an eye. It is recommended to warm up solution before burying, having taken a bottle 1-2 minutes in a hand. Side effects Up to 3% of cases – an eye, short-term burning in an eye, decrease in visual acuity, emergence of slime in the form of tyazhy, less than 1% of cases – pasting a century, hemoz, papillary conjunctivitis, hypostases a century, unpleasant feelings in an eye, an itching, pain, conjunctiva hyperaemia, emergence of follicles on a conjunctiva, a syndrome of a dry eye, an erythema a century, dacryagogue, a photophobia, a headache swelled, it is very rare – a laryngeal edema, the complicated breath. Contraindications – hypersensitivity to a levofloksatsin or to other components of drug – hypersensitivity to drugs of a hinolonovy row – pregnancy – the lactation period. Medicinal interactions the Maximum concentration of a levofloksatsin in plasma after topical administration is 1000 times less, than at oral administration therefore effects of interaction with other medicines are improbable. Special researches on interaction of eye drops Left xyhoney were not conducted. Special instructions Eye drops Left xyhoney cannot be entered subkonjyunktivalno, it is necessary to avoid direct instillation in an anterior chamber of an eye. Ftorkhinolona for system use can cause the significant allergic reactions even after single use. At emergence of allergic reaction to levofloxacin it is necessary to stop use of eye drops. Prolonged use of a levofloksatsin in the form of eye drops can lead to growth of steady microorganisms and also mushrooms. In case of deterioration or lack of improvement of a clinical picture it is necessary to cancel medicine and to start alternative therapy. Eye drops Left xyhoney contain preservative a benzalkoniya the chloride capable to collect in lenses and to have negative impact on eyes. Before use of drug of a lens it is necessary to remove and insert them anew not earlier than in 15 minutes after instillation. It is not necessary to carry contact lenses of any type in the presence of symptoms of bacterial conjunctivitis. It is necessary to apply to achievement of the best medical effect of a drop in combination with system antimicrobial therapy (except for mild cases). It is necessary to protect solution and a dropper from pollution. Use in pediatrics Efficiency and safety of use of drug for children is younger than 1 year is not studied. Pregnancy and a lactation Left xyhoney it is contraindicated to apply Eye drops at pregnancy. In need of use of drug in the period of a lactation it is necessary to resolve an issue of the breastfeeding termination. The feature of influence of medicine on ability to run the vehicle or potentially dangerous mechanisms Because of the possible disorders of vision arising right after burying drug should refuse driving and potentially dangerous mechanisms before normalization of sight. The overdose Overdose of drug in the form of eye drops is improbable. Symptoms of overdose are identical with side effects of drug. After topical administration of an excess dose of eye drops, Left xyhoney of eyes should be washed with clear (water) water of room temperature. With the significant side effects it is necessary to see a doctor. Also at intake, purposely or accidentally, symptoms can be identical with side effects. The total number of a levofloksatsin which is contained rolled into one eye drops (25 mg) is, not enough, to cause toxic reactions even after accidental intake. The form of release and packing On 5 ml of drug place in a white polyethylene bottle – a dropper and with the white screw-on protective cover supplied with a safety ring. Each bottle together with the instruction for medical use in the state and Russian languages is placed in a pack from cardboard. To Store storage conditions at a temperature not above 25ºC. To store out of children’s reach! After opening of a bottle to use drug within 28 days. 3 years not to apply a period of storage after an expiration date. Prescription status According to the prescription the Producer the Idol Ilach Dolum Sang. ve Tidzh. A.Sh., Turkey (Topkapy, Davutpasha Dzhad., Dzhebealibey Juice., No. 20 / Istanbul) according to the license Uorld Meditsin Ilach Sang. ve Tidzh. A.highway., Turkey the Owner of a trademark and the certificate of registration is the company UORLD MEDITSIN OFTALMIX ILACHLARY LTD. STI., TURKEY the Address of the organization accepting in the territory of the Republic of Kazakhstan claims from consumers on quality of products of RK, Almaty, WM Pharma Alliance LLP, Turksibsky district, Suyunbaya Ave., 222b
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