The instruction for medical use
of ALKAIN® medicine
the Trade name
the International unlicensed
name Proksimetakain Lekarstvennaya
the Drop form eye 0.5% 15 ml
contains Structure of 1 ml:
active agent – a proparakaina (proksimetakain) a hydrochloride of 5.0 mg,
excipients: a benzalkoniya chloride of 0.1% (preservative), glycerin of 24.5 mg, Acidum hydrochloricum concentrated and/or sodium hydroxide (for adjustment rn), purified water up to 1 ml.
Transparent solution, from colourless till slightly yellowish or slightly yellowish-brown color, without visible mechanical inclusions.
Drugs for treatment of diseases of eyes. Local anesthetics.
Code of automatic telephone exchange: S01HA04
Pharmacokinetics Proparakain properties easily gets into a cellular membrane and is applied as local anesthetic. After topical administration gets into a system blood stream and quickly decays in blood plasma. Proparakain is generally applied in ophthalmology and seldom causes irritation or a mydriasis.
of Alkain® is the local anesthetic of ester type used in ophthalmology. Alkain oppresses permeability of cellular membranes for sodium ions that interferes with disturbance of forming of action potential and leads to disturbance of carrying out a nervous impulse. The effect usually develops in 30 seconds after burying and remains within 15 minutes and longer.
Drug is used for local anesthesia in ophthalmology:
– measurement of intraocular pressure
– removal of foreign bodys and seams from a cornea
– diagnostic scraping from a conjunctiva
– a gonioskopichesky research.
Алкаин® it is shown as well for ensuring local anesthesia before performing surgical interventions, such as, for example, removal of a cataract.
A route of administration and doses
For removal of sutures:
1-2 drops in 2-3 minutes prior to removal of seams.
For removal of a foreign body:
1-2 drops before removal.
For carrying out a tonometriya:
1-2 drops just before measurement.
For deep anesthesia during removal of a cataract:
1-2 drops each 5-10 minutes from 5 to 7 times, before performance of a section.
After burying it is recommended to press the lacrimonasal channel or to carefully cover eyelids. It reduces system absorption of medicine and serves as prevention of development of adverse system reactions.
Patients need to be warned that did not touch eyes, there will not take place effect of anesthetic yet. It is not necessary to touch with a pipette tip eyes, or any other surface to avoid pollution of contents of a bottle.
– the irritation, pricking
– reddening of a conjunctiva
– dacryagogue, the speeded-up blinking
– an epithelial keratitis
– a cornea erosion
– threadlike infiltrates of a cornea
– an iritis
At prolonged use can be noted:
– infection and turbidity of a cornea, long loss of sight, cornea perforation.
– hypersensitivity to drug components.
This drug cannot be recommended to patients for independent treatment.
of Specific researches on incompatibility it was not carried out thereof it is not recommended to use drug along with other drugs.
Pregnant women should appoint the special instructions Pregnancy of Alkain® only if the expected therapeutic effect exceeds potential risk for a fruit.
of Alkain® is recommended to appoint to the feeding women only if the expected advantage of its use considerably exceeds potential risk.
As Alkain® contains chloride a benzalkoniya, it is necessary to delete soft (hydrophilic) lenses during burying. Lenses can be inserted not earlier than in 15 minutes after burying.
Features of influence of medicine on ability to run the vehicle or potentially dangerous mechanisms
Temporary illegibility of vision or other visual concerns after use of drug can affect an opportunity to drive the car. In this case the patient has to wait before recovery of clarity of vision before driving the car or to use mechanisms.
At local overdose it is necessary to wash out eyes plentiful amount of warm water.
At detection of any system side effects the symptomatic treatment is shown.
A form of release and packing
Eye drops of 0.5%, 15 ml, in bottles from white opaque plastic with Drop-Tainer™ dropper doser. Each bottle together with the instruction for use is packed into a cardboard box.
To Store storage conditions in vertical position at a temperature from +20 to + 80C in the fridge.
To store in the places inaccessible for children!
A period of storage
of 30 months (2.5 years)
the Expiration date after the first opening – 1 month at a temperature of storage from +20 to + 80C.
Not to apply after an expiration date.
According to the prescription
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