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Lactone-D (20 capsules)

$7.30

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Description

The instruction for medical use of LAKTON-D medicine the Trade name of Lakton-D the International unlicensed name Is not present the Dosage form of the Structure One Capsule Capsule contains active agents: spores of lactobacilli (Bacillus coagulans Unique IS-2) not less than 180 x 106, excipients: starch, calcium dibasic phosphate, lactose, talc, magnesium stearate, polyvinylpirrolidone (PVP K30), structure of the capsule: gelatin, titan dioxide (E171). Description Solid gelatin capsules of white or almost white color. Capsule contents – powder of white or almost white color Pharmacotherapeutic group Antidiarrheal drugs. Anti-diarrheal microorganisms. The microorganisms producing lactic acid. ATH code: A07FA01 Pharmacological action Pharmacokinetics of the Lactobacillus are saprophytes probiotics. A probiotics is beneficial bacteria, present at various food components and many of them colonize in intestines of the person and animals. Help a macroorganism by assistance in maintenance of a normal homeostasis of a mucous membrane with intestines of a probiotics. A probiotics not only helps to keep normal function mucous intestines, but also protects a mucous membrane from harmful factors, such as toxins, allergens and pathogenic microorganisms. The positive effect of probiotics is reached at means of several mechanisms including a cytopatronage, proliferation of cells, migration of cells, protein synthesis and an expression of genes. One of important cytoprotective effects of probiotics in a mucous membrane of intestines is strengthening of epithelial steady connections and strengthening of function of a barrier of a mucous membrane of intestines. A probiotics not only increases barrier function by synthesis of steady compounds of proteins, but also prevents destruction of these proteinaceous connections. A pharmacodynamics At intake, spores of lactobacilli are activated at low values of acidity in a stomach, then get into a duodenum where burgeon and will be transformed to vegetative cells. Lactobacilli are slowly excreted from an organism (in 10-12 days) after the reception termination. Despite temporality of finding of this microorganism in a digestive tract, the lactic acid produced at the same time makes favorable shift in the intestinal environment towards a complex of normal indestinal flora. The action mechanism as assume, is result of improvement of gastrointestinal ecology by replenishment of quantity of desirable obligate microorganisms and counteraction to pathogenic and uslovnopatogenny microbes. Two isomers of lactic acid are produced by bacteria producers: dextrorotatory (D (-) isomer of lactic acid and left-handed (L (+) isomer of lactic acid. By L (+) lactic acid it is completely metabolized in an organism, and D (-) lactic acid not completely what a certain degree of a metabolic acidosis is result of. L. sporogenes produces only L (+) isomer of lactic acid. It is supposed that L.sporogenes synthesizes bakteritsina and korotkotsepochechny fatty acids. With a growth of a microorganism there is a utilization and inclusion of cholesterol in cellular structure. Indications – disturbance of physiological flora of intestines in time and after treatment by antibiotics, streptocides, – intestinal dysbioses, – a syndrome of insufficiency of digestion, a fermentopatiya, dyspepsia – diarrhea, a meteorism, constipations – a gastroenteritis, acute and chronic colitis of various etiology – prevention of the diarrhea caused by bacteria and viruses in connection with climate change or on a travel (diarrhea of travelers). A route of administration and doses For intake. The adult appoint in 1 hour prior to food 2 capsules 2 or 3 of time a day. In case of breastfeeding to children till 1 year with intestinal gripes and slight diarrhea the dose makes from 1/3 to ½ capsules some or twice a day, is accepted, before feeding by a breast. For children the capsule can be opened and to mix contents of the capsule with a small amount of semi-fluid or liquid food of room temperature. It is not recommended to dissolve drug in hot water. Unused mix should not be stored for the subsequent use. At children and teenagers of 1-18 years the dose makes 1-2 capsules some or 2 times a day. Duration of administration of drug depends on a disease and is defined by the doctor. Use duration: at a long and chronic course of dysentery, post-dysenteric colitis, in the period of a convalescence after acute intestinal infections and also in long intestinal dysfunction of an unspecified etiology – within 4 weeks, in nonspecific ulcer colitis and also chronic colitis and coloenterites treatment – up to 1.5 – 2 months, in dysbacterioses of various etiology – 4 weeks. For fixing of the gained clinical effect in 10-14 days after the termination of a course of treatment in the absence of full normalization of microflora appoint maintenance doses of drug (on 1 capsule 2 times a day the adult) within 1-1.5 months. In the diseases proceeding with a recurrence repeated courses of treatment are reasonable. In these cases before prescribing of drug the repeated research of microflora is necessary. In view of a high antibiotikoustoychivost of spore-forming lactobacilli the use of Laktona-D does not interfere with antibiotic treatment. Side effects – allergic reactions – skin rash of the Contraindication – hypersensitivity to drug components – malignant diseases – children’s age up to 1 month. Medicinal interactions the Concomitant use of antioxidants and antineoplastic drugs reduces therapeutic effect since Lakton-D can reduce the level of content of these drugs in blood plasma. The special instructions Drug it should not be appointed to the patients receiving immunosuppressive therapy since Lactobacillus sporogenes increase immunity. Pregnancy and a lactation Use of drug at pregnancy and in the period of a lactation (breastfeeding) is considered safe. Features of influence of medicine on ability to run the vehicle or potentially dangerous mechanisms. Drug does not affect ability to run the vehicle or potentially dangerous mechanisms. The overdose is not revealed. The form of release and packing On 10 capsules place in blister strip packaging from a film of polyvinylchloride and aluminum foil. On 2 packs together with the instruction for medical use in the state and Russian languages place in a pack from cardboard. Storage conditions In original packing, in the dry place at a temperature not above 25 °C. To store out of children’s reach! An expiration date 3 years After an expiration date not to apply Prescription status Without prescription Protech Biopharma Pvt Producer. Ltd., Registered Office: Dilkash Guest House, Alsafa Market, SariaBala, Srinagar 190001 (J and K), India Owner of the registration certificate of Protech Biopharma Pvt. Ltd., India the Name, the address and a contact information (phone, the fax, e-mail) of the organization in the territory of the Republic of Kazakhstan accepting claims (offer) on quality of medicines from consumers and responsible for post-registration observation of safety of medicine Republic of Kazakhstan, Almaty, Utegen St. of the batyr, 13

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