the Trade name
the International unlicensed name
Is not present
the Dosage form
of the Tablet, coated 0.1 g and 0.2 g
One tablet contains
active agent – Antralya® in terms of dry matter of 100 mg (0.1 g) or 200 mg (0.2 g),
excipients: magnesium carbonate heavy, potato starch, krospovidon XL 10 (Polyplasdone XL 10), cellulose microcrystalline 101, K 29/32 povidone, polysorbate-80 (twin-80), aerosil, calcium stearate,
structure of a cover: Opadry II 85 G 18490 white (polyvinyl alcohol, polyethyleneglycol, talc, lecithin, titan dioxide (E 171)),
Opadry II 85 G25557 red (karmoizin aluminum varnish (E 122), FD&C blue #2 aluminum varnish (E 132), ferrous oxide red (E 172), titan dioxide (E 171), lecithin, polyethyleneglycol, talc, polyvinyl alcohol).
of the Tablet of round shape with a biconvex surface, coated, dark red color.
The pharmacotherapeutic group
Drugs for treatment of diseases of a liver
the Code of automatic telephone exchange A05B A
Pharmacokinetics Maximum Concentration properties of drug in blood is marked out in 3-4 h after use, elimination half-life – 4-5 h. Drug is removed with urine and a stake.
of Antral® belongs to group of hepatoprotective drugs. It is effective in treatment of acute and chronic hepatitises of various genesis, liver cirrhoses, promotes reduction of astenovegetativny disturbances, improves appetite, a dream, reduces the dispeptic phenomena. At course use, drug normalizes the content of bilirubin, γ-globulins, cholesterol in blood, the prothrombin ratio, activity of transaminases (AlAT and AsAT) and alkaline phosphatase. Антраль® possesses prolonged the anti-inflammatory, anesthetizing actions. Антраль® promotes alleviation of the consequences of influence of hepatotoxins, activization of reparative processes in hepatocytes and practical normalization of indicators of a structurally functional condition of a liver. Drug inhibits processes of peroxide oxidation of lipids in blood and fabrics, maintains activity of antioxidant systems of an organism, causes stabilization of structure of a liver and membranes of hepatocytes.
– acute and chronic hepatitises of various etiology (virus, alcoholic, medicamentous, toxic)
– fat dystrophy and cirrhoses of a liver
– inflammatory diseases of a gall bladder, spleen, pancreas
– a resection of a gall bladder
– prevention of diseases of a liver owing to harmful effects of toxins of various etiology: alimentary toxins, medicines, chemotherapy, radiation therapy.
The route of administration and doses
of Antral® appoint inside, after a meal 3 times a day:
– to adults and children 10 years are more senior – on 200 mg on reception, in cirrhosis: in the first week of treatment – on 400 mg on reception, then 2-3 weeks – on 200 mg on reception,
– to children at the age of 4-10 years (including in cirrhosis) – on 100 mg on reception.
Duration of treatment depends on weight of a disease. The average course of treatment makes 3-4 weeks. The course of treatment should be repeated in 3-4 weeks.
It is recommended to accept Antral® in 20-30 minutes after a meal, with a moderate amount of water.
Drug, is well transferred by patients.
– dispepsichesky phenomena.
– disturbance of secretory function of kidneys
– individual hypersensitivity to drug components
– pregnancy and the period of a lactation
– the children’s age up to 4 years
of Antral® is well compatible to antibacterial, detoksitsiruyushchy, bile-expelling, vitamin drugs that allows to include it in complex therapy. At simultaneous use for patients with cirrhosis of Antral® does not affect activity of steroid and cytostatic drugs, reduction (up to 50-70%) earlier used dose of steroids without further decrease in efficiency of treatment is allowed.
instructions Use in pediatric practice
In this dosage form do not appoint drug to children under 4 years.
Features of influence of medicine on ability to run the vehicle or potentially dangerous mechanisms
Drug does not affect ability to run the vehicle or to work with potentially dangerous mechanisms.
Symptoms: strengthening of side effects.
Treatment: it is necessary to wash out a stomach and (in case of need) to carry out symptomatic treatment.
Form of release and packing
Form of release and packing
of the Tablet, coated 0.1 g or 0.2 g. On 10 tablets in blister strip packaging (blister). On 3 blister strip packagings (blister) together with the instruction for use in a cardboard pack.
To Store storage conditions in the dry, protected from light place, at a temperature not above 25 °C.
To store out of children’s reach!
A period of storage
it is not necessary to use Drug after the termination of the expiration date specified on packing.
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