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Lactofiltrum® (Lignin hydrolised + Lactulose) 30 tablets





One tablet contains active ingredients:

  • Hydrolysis lignin (in terms of dry matter) – 355 mg;
  • Lactulose (in terms of 100% substance) – 120 mg;

Excipients: croscarmellose sodium, magnesium stearate, microcrystalline cellulose


Pharmacological properties


Lignin is not absorbed in the gastrointestinal tract, it is completely eliminated from the intestine within 24 hours. Lactulose in the stomach and upper intestines is not absorbed and hydrolyzed by the enzymes of the small intestine, it enters the lower gastrointestinal tract, where it is decomposed by beneficial microflora enzymes.


The pharmacological action of the drug is due to the properties that make up the active components – lignin and lactulose.

Hydrolytic lignin is a natural enterosorbent, consisting of hydrolysis products of wood components, has a high sorption activity and non-specific detoxification effect. Binds in the intestines and removes from the body pathogenic bacteria and bacterial toxins, drugs, heavy metal salts, alcohol, allergens, as well as an excess of certain metabolic products, including bilirubin, cholesterol, histamine, serotonin, urea, and other metabolites responsible for development of endogenous toxicosis. Not toxic.

Lactulose is a synthetic disaccharide, the molecule of which consists of residues of galactose and fructose. Lactulose released from the tablets in the large intestine as a substrate is fermented by normal intestinal microflora, stimulating the growth of bifidobacteria and lactobacilli. As a result of the hydrolysis of lactulose in the large intestine, organic acids are formed – lactic, acetic and formic, which inhibit the growth of pathogenic microorganisms and, as a result, reduce the production of nitrogen-containing toxic substances. The described process leads to an increase in osmotic pressure in the lumen of the large intestine and stimulation of peristalsis. The complex effect of the drug is aimed at normalizing the microbiocenosis of the large intestine and reducing the intensity of endogenous toxic conditions.

The use of the drug in the complex therapy of bacterial vaginosis (vaginal dysbiosis) leads to an increase in the effectiveness of therapy, including an increase in the number of lactobacilli in the vagina, as well as an effective suppression of the growth of opportunistic flora.


Indications for use

– intestinal dysbacteriosis, including as a result of antibiotic therapy

As part of complex therapy:

– irritable bowel syndrome

– acute and chronic hepatitis and cirrhosis of the liver

– allergic diseases (atopic dermatitis, urticaria)

– vaginal dysbiosis.


Dosage and administration

Inside, children under 6 years old – pre-grind and dissolve in 50 ml of purified water. Adults and children from one year old – one hour before meals and taking other medicines:

With intestinal dysbacteriosis:

– adults and children over 12 years old – 2-3 tablets 3 times a day,

– children from 8 to 12 years old – 1-2 tablets 3 times a day,

– children from 3 to 7 years – 1 tablet 3 times a day,

– children from 1 to 3 years old – 1/2 tablet 3 times a day.

For bacterial vaginosis (vaginal dysbiosis):

2 tablets 3 times a day.

The average duration of the course of treatment is 2-3 weeks.

Long-term use of the drug and repeated courses of treatment should be carried out only on the advice of a doctor.


Side effects

Possible allergic reactions (skin rash, hives)

Rarely – flatulence, diarrhea



– individual intolerance to the components of the drug
– bowel obstruction
– gastrointestinal bleeding
– galactosemia
– exacerbation of peptic ulcer of the stomach and duodenum 12
– intestinal atony


Drug Interactions

Perhaps a decrease in the therapeutic effect of some concomitantly taken orally drugs.


Special instructions

The drug can be used in complex therapy in conjunction with other drugs, subject to the rule of separate administration.

Pregnancy and lactation

There are no data on the use of the drug during pregnancy and lactation.

Features of influence on the ability to drive a car or potentially dangerous mechanisms

Not known



Symptoms: constipation, abdominal pain.

Treatment: drug withdrawal.


Storage conditions

Store in a place protected from moisture and light at a temperature not exceeding 30 ° C.
Keep out of the reach of children!
Shelf life – 3 years
Do not use the drug after the expiration date.


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