The instruction for medical use
of Anestezol® medicine
the Trade name
the International unlicensed name
Is not present
the Dosage form
1 suppository contains
active agents: benzocaine of 100 mg
of bismuth subgallate of 40 mg
left menthol of 4 mg
of zinc oxide of 20 mg,
excipients: a polietilenoksidny basis (Makrogol-1500 (95%), Makrogol – 400 (5%)) – before receiving a suppository weighing 2.60 g.
Suppositories of yellow or chartreuse color, a torpedo-shaped form
of Means for treatment of hemorrhoids and anal cracks for topical administration. Local anesthetics
the ATX C05AD Code
Pharmacokinetics Benzocaine properties, zinc oxide and left menthol are practically not absorbed.
Bismuth subgallate – absorption insignificant. Removal of the soaked-up part – generally kidneys, but a number can keep in bones and fabrics (it is capable to kumulirovat, causing an intoxication syndrome). Bismuth gets through a placenta.
the Combined drug, renders the mestnoanesteziruyushchy, antiseptic, knitting and drying action.
Benzocaine – local anesthetic for surface anesthesia. Reduces permeability of a cellular membrane for sodium, forces out from the receptors located on an internal surface of a membrane blocks carrying out local impulses. Interferes with emergence of painful impulses in the terminations of sensory nerves and to their carrying out on nerve fibrils.
Bismuth subgallate – antiseptic, has the knitting, drying, analgeziruyushchy effect. Causes consolidation of colloids (coagulation of proteins) of extracellular liquid, slime, exudate, cellular membranes. The film which is formed at the same time protects the terminations of sensory nerves from irritation, reduces pain, limits or interferes with edematization. Causes local vasoconstriction, reduces their permeability, exudation, reduces intensity of inflammatory process. Does not irritate fabrics (the formed albuminates poorly are dissociated).
Zinc oxide – anti-inflammatory local drug, renders the drying, adsorbing, knitting and antiseptic action. Forms, albuminates and denatures proteins. When drawing reduces the phenomena of exudation, inflammation and irritation of fabrics by the struck surface, forms a protective barrier from action of the irritating factors.
Left menthol – local irritative means which effect is generally caused by the reflex reactions connected with irritation of sensitive receptors of mucous membranes. Renders the easy mestnoanesteziruyushchy (‘distracting’) action, has weak antiseptic properties.
– anal fissures
the Route of administration and
Rektalno’s doses, after spontaneous bowel emptying or a cleansing enema.
To adults and children 12 years on 1 suppository 1–2 times a day are more senior.
Course of treatment of 10 days.
– burning in an anus
– laxative effect
– allergic reactions
of the Contraindication
– hypersensitivity to drug components
– children’s age up to 12 years
are not revealed
instructions Pregnancy and a lactation
Use during pregnancy and a lactation is possible if the expected advantage of use of drug for mother exceeds potential risk for a fruit and the child.
The feature of influence of medicine on ability to run the vehicle or potentially dangerous mechanisms
does not affect ability to run the vehicle or potentially dangerous mechanisms.
is not revealed
the Form of release and packing
On 5 suppositories place in blister strip packaging from a film polyvinylchloride, laminated by polyethylene.
On 2 planimetric packs together with the instruction for medical use in the state and Russian languages put in a pack from cardboard.
To Store storage conditions the place protected from light at a temperature not above 20 °C.
To store out of children’s reach!
not to apply a period of storage after an expiration date.
ProizvoditelOAO’s prescription Nizhpharm, Russian Federatsiya603950, Nizhny Novgorod, GSP-459, Salganskaya St., 7 ph.: (831) 278-80-88 fax: (831) 430-72-28веб the website: http://www.nizhpharm.ru
the Name and the country of the owner registration udostovereniyaoao Nizhpharm, the Russian Federation
the Address of the organization accepting in the territory of the Republic of Kazakhstan claims from consumers on quality of products (goods) Representative office of JSC Nizhpharm 050043, Republic of Kazakhstan, Almaty, mdt. Khan-Taniri, 55b ph.: (727) 2222-100fax: (727) 398-64-95e–mail: email@example.com