Antivirals / External Use

Ulkaril 5g of 2% cream

Brands: Nobel AFF (Kazakhstan)

$5.50

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Ulkaril 5g of 2% cream quantity

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Brands:: Nobel AFF (Kazakhstan)

Description

The instruction for medical use of ULKARIL® medicine Trade name УЛКАРИЛ® the International unlicensed name Acyclovir Dosage Form 5% Cream Structure of 1 G of Cream contains active agent – acyclovir of 50 mg, excipients: cetostearyl alcohol, half-oxameasures 407, vaseline white, oil mineral, propylene glycol, sodium lauryl sulfate, water purified. The description Homogeneous emulsion cream (oil in water) soft creamy smooth consistence, with a characteristic smell of white or whitish color, without visible inclusions. Pharmacotherapeutic group Antibacterial drugs and antimicrobial drugs for treatment of diseases of skin. Antimicrobial drugs for topical administration. Antiviral drugs. Acyclovir the ATX D06BB03 Code the Pharmacological Pharmacokinetics At properties topical administration acyclovir is slightly soaked up through skin and mucous membranes. The pharmacodynamics the Acyclovir entering ULKARIL® cream is a synthetic analog of a nucleoside of thymidine. The thymidinekinase of the cells infected with a virus, will actively transform acyclovir through a number of consecutive reactions to mono – di – and acyclovir triphosphate. Triphosphate of acyclovir is built in instead of a deoxyguanosine virus DNA, inhibits a DNA polymerase of the last and suppresses replication process. In herpes acyclovir prevents formation of new elements of rash, reduces the probability of skin dissimination and visceral complications, accelerates formation of crusts. Promotes decrease in pain in a sharp phase of the surrounding herpes. The specificity and very high selectivity of action is also caused by its primary accumulation in the cells affected with a herpes virus. Indications – infections of lips and the persons called by the Herpes simplex virus of types 1 and 2. A route of administration and doses Adults and children need to apply cream on an affected area of 5 times a day each 4 hours, excepting night time. Treatment needs to be begun at the first symptoms of an infection – during a prodromal stage. Course of treatment not less than 4 days. Treatment can be continued up to 10 days, in case of lack of healing, follows will see a doctor. Before putting cream it is necessary to wash up hands, it is important not to pound affected areas and not to touch them with a towel not to cause deteriorations in a course of the disease or transmission of infection. For avoidance of spread of a virus on other sites of skin it is necessary to use a fingerstall or rubber gloves. Side effects – it is not frequent (≥ 1/1000 and & lt, 1/100): reddening, an itching, peeling, burning on sites of putting drug – is rare (≥ 1/10000 and & lt, 1/1000): an erythema, the contact dermatitis more often connected with reaction to auxiliary components of drug – it is very rare (& lt, 1/10000): reactions of immediate hypersensitivity, including a Quincke’s disease of the Contraindication – hypersensitivity or intolerance of components of drug Medicinal interactions At external use of Ulkaril® the interaction with other medicines is not revealed. Special instructions it is not necessary to exceed the recommended dosage, frequency of appliques and duration of treatment. 5% Ulkaril® cream should not be applied to prevention of a recurrence of the infection caused by a herpes simplex virus. To the persons having herpes on lips (especially in the presence of open defeats), it is necessary to follow strictly rules of precaution not to allow infection of other people. 5% Ulkaril® cream is intended only for drawing on integuments, it an eye is not recommended to apply on mucous membranes of an oral cavity, genitalias as development of the significant local inflammation is possible. The efficiency of treatment at cream use by that will be higher, than earlier it is begun Pregnancy and the period of a lactation women Should be careful when prescribing Ulkaril® cream during pregnancy and to estimate expected advantage for mother and possible risk for a fruit. It is unknown whether acyclovir gets into breast milk at topical administration therefore the feeding women should appoint Ulkaril® cream with care. Use in pediatrics of Restrictions to use at children’s age is not present. Features of influence of medicine on ability to run the vehicle or potentially dangerous mechanisms of 5% Ulkaril® cream does not affect ability to run the vehicle and work with potentially dangerous mechanisms. Overdose About cases of overdose of 5% of ULKARIL® cream it was not reported. The form of release and packing On 2 g and 10 g of drug place in tubas aluminum with a plastic cap. On 1 tuba together with the instruction for medical use in the state and Russian languages place in a pack from cardboard with the hologram of firm – producer. To Store storage conditions in the dry, protected from light place, at a temperature not over 25 ºС. To store out of children’s reach! 2 years not to apply a period of storage after the expiry date specified on packing. Prescription status Without prescription the Producer/owner of the registration certificate of JSC Nobel Almatinskaya Pharmatsevticheskaya Fabrika Republic of Kazakhstan Almaty, Shevchenko St., 162 E. The address of the organization accepting in the territory of the Republic of Kazakhstan claims from consumers on quality of products (goods) and responsible for post-registration observation of safety of medicine: JSC Nobel Almatinskaya Pharmatsevticheskaya Fabrika Republic of Kazakhstan, Almaty, Shevchenko St., 162 E Phone number: (+7 727) 399-50-50 Fax number: (+7 727) 399-60-60 E-mail address: nobel@nobel.kz

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