FREE Shippingto US, AU, UK and EU on all orders over $149
/ / /

Arbidol® (Umifenovir) 50 mg, 10 tabs

$15.00

b684127c7718
Brands

Description

Composition

One tablet contains the active substance – umifenovir (umifenovir hydrochloride monohydrate (arbidol) in terms of umifenovir hydrochloride) 50 mg

Pharmacological properties

Pharmacokinetics

Umifenovir is rapidly absorbed and distributed to organs and tissues. The maximum concentration in blood plasma when taken at a dose of 50 mg is achieved after 1.2 hours, at a dose of 100 mg – after 1.5 hours. It is metabolized in the liver. The half-life is 17-21 hours. About 40% is excreted unchanged, mainly with bile (38.9%) and in a small amount by the kidneys (0.12%). During the first day, 90% of the administered dose is excreted.

Pharmacodynamics

Arbidol® is an antiviral agent. Specifically inhibits influenza A and B viruses, a coronavirus associated with severe acute respiratory syndrome. By the mechanism of antiviral action, it belongs to fusion inhibitors (fusion), interacts with the hemagglutinin of the virus and prevents the fusion of the lipid membrane of the virus and cell membranes. It has a moderate immunomodulatory effect. It has interferon-inducing activity, stimulates humoral and cellular immune responses, phagocytic function of macrophages, increases the body’s resistance to viral infections. Reduces the incidence of complications associated with a viral infection, as well as exacerbations of chronic bacterial diseases.

Therapeutic efficacy in viral infections is manifested in a decrease in the severity of general intoxication and clinical phenomena, and a reduction in the duration of the disease. Refers to low-toxic drugs. Does not have any negative effects on the human body when taken orally in recommended doses.

Indications for use

– influenza A and B, acute respiratory viral infections (ARVI), severe acute respiratory syndrome (SARS) (including those complicated by bronchitis, pneumonia) – secondary immunodeficiency states of the T-cell and humoral type – as part of the complex therapy of chronic bronchitis, pneumonia and recurrent herpes infection
– prevention of influenza and ARVI during the epidemic season

– prevention of postoperative infectious complications and normalization of the immune status – as part of the complex therapy of acute intestinal infections of rotavirus etiology in children over 6 years of age.
Inside, on an empty stomach (half an hour before or 2 hours after a meal).

Single dose: children from 6 to 12 years old – 100 mg (2 tablets), children over 12 years old and adults – 200 mg (4 tablets).

For non-specific prophylaxis

In direct contact with patients with influenza and other acute respiratory viral infections – children from 6 to 12 years old – 100 mg once a day, over 12 years old and adults – 200 mg once a day for 10-14 days.

During an epidemic of influenza and other acute respiratory viral infections, to prevent exacerbations of chronic bronchitis, recurrence of herpes infection – children from 6 to 12 years old – 100 mg each, over 12 years old and adults – 200 mg 2 times a week for 3 weeks.

For the prevention of SARS (in contact with a patient) – children from 6 to 12 years old – 100 mg once a day, adults and children over 12 years old are prescribed 200 mg once a day for 12-14 days.

Prevention of postoperative complications – children from 6 to 12 years old – 100 mg, children over 12 years old and adults – 200 mg once 2 days before surgery, then in the same dose once on the second and fifth days after surgery.

For treatment

Influenza, other acute respiratory viral infections without complications – children from 6 to 12 years old – 100 mg 4 times a day, over 12 years old and adults – 200 mg 4 times a day for 5 days.

Influenza, other acute respiratory viral infections with the development of complications (bronchitis, pneumonia) – children from 6 to 12 years old – 100 mg 4 times a day, over 12 years old and adults – 200 mg 4 times a day for 5 days, then a single dose 1 once a week for 4 weeks.

Severe acute respiratory syndrome (SARS) – for adults and children over 12 years old – 200 mg 2 times a day for 8-10 days.

In the complex treatment of chronic bronchitis, herpes infection – children from 6 to 12 years old – 100 mg 4 times a day, over 12 years old and adults – 200 mg 4 times a day for 5-7 days, then a single dose 2 times a day week for 4 weeks.

In the complex therapy of acute intestinal infections of rotavirus etiology – children from 6 to 12 years old – 100 mg 4 times a day, over 12 years old – 200 mg 4 times a day for 5 days.

Side effect

Rarely

– allergic reactions (rash, anaphylactic reaction)

Contraindications

– hypersensitivity to any component of the drug
– children under 6 years old
– pregnancy and lactation

Drug interactions

When administered with other drugs, no negative effects were noted.

 

Special instructions

Pregnancy and lactation

Due to the lack of the necessary clinical experience, it is not recommended to take the drug Arbidol® during pregnancy, unless the potential benefit to the mother outweighs the potential risk to the fetus. Due to the lack of need given clinical experience, it is not recommended to take the drug Arbidol during breastfeeding.

Features of the influence of the drug on the ability to drive a vehicle or potentially dangerous mechanisms.

It does not show central neurotropic activity and can be used in people of various professions, incl. requiring increased attention and coordination of movements (transport drivers, operators, etc.).

 

Storage conditions

Store at a temperature not exceeding 25 ° C.
Keep out of the reach of children!

Shelf life – 2 years
Do not use after the expiration date indicated on the package!

Additional information

Ingredient

Reviews

There are no reviews yet.

Be the first to review “Arbidol® (Umifenovir) 50 mg, 10 tabs”

Your email address will not be published. Required fields are marked *

Wishlist 0
Open wishlist page Continue shopping