Dermatology / Hormonal, Anti-Inflammatory Drugs / Psoriasis and keratosis

Moderm 0.1% 15g ointment tube

Brands: Farmak (Ukraine)

$13.90

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Moderm 0.1% 15g ointment tube quantity

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72ff7160e6ff

Brands:: Farmak (Ukraine)

Description

The instruction for medical use

of MODERM medicine

the Trade name
Moderm

Mezhdunarodnoye the unlicensed

name Mometazon Lekarstvennaya a form
Ointment of 0.1%

Structure
of 100 g of ointment contain
active agent – a mometazon of furoate in terms of 100% substance
of 0.1 g,
excipients: hexyleneglycol, propylene glycol mono-palmitostearat, wax white, the phosphoric acid divorced, paraffin white soft (vaseline), water cleaned.

The description
Ointment of white or almost white color

Pharmacotherapeutic group
Glucocorticosteroids for topical treatment of diseases of skin. Glucocorticosteroids active (group III).
The code of automatic telephone exchange D07AC13

the Pharmacological

Pharmacokinetics Degree properties of penetration of corticosteroids of topical administration through skin depends on many factors, including composition of drug and integrity of an epidermal barrier. In 8 hours after putting ointment on the uninjured skin (without occlusive bandage) system absorption is about 0.7%. Injury of skin, existence of inflammatory process and use with an occlusive bandage, lead to strengthening of penetration of drug through skin. Because children have a size of a ratio of surface area and body weight it is more, than at adults, at children higher absorption of drug is revealed.
The pharmacodynamics
Moderm ointment is the highly effective synthetic corticosteroid possessing anti-inflammatory, antipruritic, anti-exudative and vasoconstrictive action. GKS induces discharge of the proteins inhibiting a phospholipase of A2 and known under the general name of a lipokortina which control biosynthesis of such mediators of inflammation as prostaglandins and leukotrienes, by slowing down of release of their common precursor, arachidonic acid.
Corticosteroids suppress an accumulation and further migration of cells in the field of damage and also eliminate expansion and hyperpermeability of vessels in the field of damage that reduces access of cells to sites of damage of fabrics.
In addition corticosteroids can also prevent access of sensibilized T lymphocytes and macrophages to target cells. Anti-proliferative action reduces a hyperplasia of cells in psoriasis.

Indications
– the inflammatory phenomena and an itching at the dermatosis demanding therapy by glucocorticosteroids
– the states which are followed by a hyperkeratosis (atopic and seborrheal dermatitis, psoriasis, chronic eczema)
– allergodermatoza

the Route of administration and doses
apply a Thin film of ointment on affected areas of skin once a day.
Duration of treatment is established by the doctor, proceeding from the diagnosis, efficiency of treatment, presence of side effects and also tolerance of drug patients.
Side effects
At skin appliques of drug can arise the following local reactions:
Seldom
– irritation and xeroderma, a folliculitis, a hypertrichosis, acne rash, hypopigmentation, perioral dermatitis, allergic contact dermatitis, consecutive infection, striya and a heat rash
Very seldom
– burning, an itching, a skin atrophy, appearance of pink eels
the Probability of emergence of the listed undesirable phenomena increases at use of occlusive bandages.

Contraindications
– hypersensitivity to any component of drug
– children’s age up to 2 years
Medicinal interactions
of Interaction with other medicines are not described so far. On chemical properties of a mometazon furoate is not compatible to alkalis.

The special
instructions Drug Moderm, ointment of 0.1% it is intended only for skin use in dermatology and not intended for use in ophthalmology.
Use of ointment is preferable at the sharp, chronic dermatosis which is followed by dryness and peeling.
If it is not offered the doctor, drug should not be put on a face and also in the field of axillary and inguinal folds.
In case of development of the accompanying infection of skin it is necessary to apply the appropriate antifungal or antibacterial agent.
If within 2 weeks after the beginning of therapy the improvement does not happen, it is necessary to specify the diagnosis.
Use in pediatrics
Because children have a size of a ratio of surface area and body weight is more, than at adults, children are subject to bigger risk of suppression of function gipotalamo – a hypophysial and adrenal system and ment of a syndrome of Cushing at external use of GKS. Long-term treatment of children of GKS can lead to disorder of growth and development. Children have to receive the minimum dose of drug sufficient for achievement of effect.
Moderm ointment should not be applied to treatment of the dermatitis caused by wearing diapers.
Pregnancy and the period of a lactation
Moderm ointment is applied at pregnant women only when the expected advantage for mother exceeds potential threat for a fruit. The feeding women need to interrupt breastfeeding for drug treatment.

Overdose
Symptoms: system absorption can lead to emergence of system effects.
Treatment: symptomatic.

A form of release and packing
Ointment of 0.1% on 15 g in tubas aluminum. Each tuba together with the instruction for medical use in the state and Russian languages is placed in a pack from cardboard.

To Store storage conditions at a temperature not above 25 °C.
To store out of children’s reach.

A period of storage
2 years
it is not necessary to use drug after the termination of the expiration date specified
on packing.

Prescription status
According to the prescription

JSC Pharmak Adres Producer: Ukraine, 04080, Kiev, st. of Frunze, 63.

The address of the organization accepting in the territory of the Republic of Kazakhstan claims from consumers on quality of products (goods)
Republic of Kazakhstan, 050031 Almaty, Tolya St. bi 291 A, letter L, office 25.
Ph. / fax: +7 (727) 256-66-36 (26)
E-mail address: znamer@ukr.net

Additional information