Rumalon® (IM) 1 ml, 25 ampoules

What Is Rumalon 1 ml Injection?

Rumalon 1 ml is an injectable medicine used to treat degenerative and dystrophic diseases of the joints and musculoskeletal system. It contains a glycosaminoglycan-peptide complex derived from animal bone marrow and rib cartilage extracts. Rumalon is indicated for conditions such as knee osteoarthritis, hip osteoarthritis, spondylosis, and other degenerative joint disorders. The medicine is administered by deep intramuscular injection according to a specific treatment schedule. Each ampoule contains 1 milliliter of solution, and the package includes 25 ampoules. Rumalon belongs to the pharmacotherapeutic group of medicines used for musculoskeletal disorders. Before beginning treatment, a healthcare professional should assess the patient's condition and exclude systemic autoimmune diseases that require different treatment approaches.

What Conditions Is Rumalon Used For?

Rumalon is indicated for degenerative and dystrophic diseases affecting joints and cartilage. These conditions include:

• Gonarthrosis, or knee osteoarthritis.
• Coxarthrosis, or hip osteoarthritis.
• Osteoarthritis of the interphalangeal joints.
• Spondylosis, involving degenerative spinal changes.
• Spondyloarthrosis, affecting the spinal joints.
• Meniscopathy, affecting the knee meniscus.
• Chondromalacia patellae, involving cartilage beneath the kneecap.

What Are the Ingredients in Rumalon?

Each 1 milliliter ampoule contains Rumalon extract consisting of a mixture of bone marrow and rib cartilage extracts. The extract contains a glycosaminoglycan-peptide complex with a minimum content of 2.25 milligrams. Additional ingredients include hydrochloric acid solution. The medicine also contains metacresol, which may cause allergic reactions in sensitive individuals.

How Is Rumalon Administered?

Rumalon is administered by deep intramuscular injection. The recommended dosing schedule follows a gradual increase in the amount administered:

1. First day: 0.3 milliliters.
2. Second day: 0.5 milliliters.
3. Subsequent injections: 1 milliliter three times weekly.

The standard treatment course lasts 5 to 6 weeks. A repeated course may be considered after consultation with a physician, following the same schedule. No cases of Rumalon overdose have been reported.

Who Should Not Use Rumalon?

Rumalon must not be used in the following circumstances:

• Hypersensitivity to any ingredient.
• Rheumatoid arthritis.
• Age under 18 years.
• Pregnancy or breastfeeding.
• Women of reproductive age who do not use reliable contraception.

Before treatment, a physician should exclude systemic autoimmune disorders, including rheumatoid arthritis, ankylosing spondylitis, systemic lupus erythematosus, and scleroderma. These conditions require specific medical treatment.

What Side Effects Can Rumalon Cause?

Rare adverse reactions include allergic reactions, anaphylactoid reactions, and anaphylactic shock. Severe allergic reactions require immediate medical attention. If unexpected adverse effects develop, treatment should be discontinued and a healthcare professional contacted.

Can Rumalon Interact With Other Medicines?

Rumalon may be used alongside nonsteroidal anti-inflammatory medicines and glucocorticosteroids. However, simultaneous use with indirect anticoagulants, antiplatelet agents, or fibrinolytic medicines may increase their effects. Frequent monitoring of blood coagulation parameters is necessary when these medicines are combined.

Does Rumalon Affect Driving Ability?

According to the product information, Rumalon does not affect the ability to drive vehicles, operate machinery, or perform activities requiring concentration and rapid psychomotor responses.

How Should Rumalon Ampoules Be Stored?

Store Rumalon at a temperature not exceeding 25°C (77°F), protected from light.

Keep out of reach of children. Shelf life: 5 years.

Do not use after the expiration date.

What Does the Rumalon 1 ml Package Contain?

Rumalon 1 ml, 25 ampoules contains five blister packs with five dark-glass ampoules each.

Every ampoule contains 1 milliliter of injectable solution.

The liquid is clear or slightly opalescent, light yellow with a brownish tint, and has a characteristic metacresol odor.

The solution should contain no visible particles.