Levomekol® Ointment (Methyluracil + Chloramphenicol) 40g tube

Composition

1 g of ointment contains active ingredients:

• Dioxomethyltetrahydropyrimidine (methyluracil) 40mg


• Chloramphenicol - 7.5 mg,

Excipients: macrogol - 1500, macrogol - 400.

 

Pharmacological properties

Pharmacokinetics

The drug easily penetrates deep into tissues without damaging biological membranes.

Pharmacodynamics

Combined preparation for topical use, has antimicrobial, anti-inflammatory (dehydrating) effect, is active against gram-positive and gram-negative microorganisms - staphylococci, Pseudomonas aeruginosa and Escherichia coli. Stimulates regeneration processes.

In the presence of pus and necrotic tissues, the antibacterial effect of the drug is preserved. The dehydration effect of polyethylene glycol, which is part of the drug, is ten times greater than the effect of a hypertonic saline solution.

 

Indications for use Levomekol

Local treatment of purulent wounds infected with mixed microflora (including staphylococci, Pseudomonas aeruginosa and Escherichia coli) in the first (purulent-necrotic) phase of the wound process.

 

Dosage and administration

locally. The ointment is impregnated with sterile gauze wipes, which loosely fill the wound after its standard surgical treatment (mechanical removal of necrotic tissues, washing with hydrogen peroxide solution).

It is possible to administer the drug into the purulent cavities through a catheter (drainage tube) using a syringe. In this case, the ointment is preheated to 35-36 ºС. Dressings are performed daily, once a day, until the wound is completely cleansed of purulent-necrotic masses. For large wound surfaces, the daily dose of ointment in terms of chloramphenicol should not exceed 3 g.

The duration of treatment depends on the severity and course of the disease, and is prescribed by a doctor.

 

Possible side effects

Allergic reactions (skin rashes)

 

Contraindications

• Hypersensitivity to the components of the drug


• Children's age up to 1 year

 

Drug Interactions

Cases of interaction or incompatibility with other drugs are not described.

 

Special instructions

Avoid getting the drug on mucous membranes and open wounds.

Childhood

In newborns, the biotransformation of chloramphenicol is slower than in adults. In this regard, the drug is not recommended for use in children under the age of 1 year.

Pregnancy and lactation

In experimental studies of chloramphenicol, a risk to the fetus (embryotoxic effect) has been identified. Controlled clinical studies in pregnant women have not been conducted. In this regard, the use of the drug Levomekol during pregnancy is not recommended.

Chloramphenicol is excreted in breast milk. During lactation, you should either stop using the drug, or breastfeeding.

Features of the effect of the drug on the ability to drive a car or potentially dangerous mechanisms

Does not affect the ability to drive a car or potentially dangerous machinery.

 

Storage conditions

Store at a temperature not exceeding 20°C.
Keep out of the reach of children!
Shelf life - 3 years 6 months.
Do not use the drug after the expiration date.