Fanigan® Fast Gel, 30g

  • $12.00
Sku: e3b20ecd8185
The instruction for medical use

of FanIganTM Fast medicine

the Trade name
FanIganTM Fast

the International unlicensed name
Is not present

the Dosage form
Gel for external use

1 gram of gel contains
active agents: diclofenac diyetilenamin 11.6 mg that

linseed oil of 30 mg,
excipients is equivalent to diclofenac of sodium of 10 mg menthol of 50 mg methyl salicylate of 100 mg: propylene glycol, carbomer 940, sodium edetat, polysorbate 80, sodium hydroxide, methylparahydroxybenzoate, propilparagidroksibenzoat, the water purified.

The description
Uniform gel of white color with a characteristic smell

Pharmacotherapeutic group
Non-steroidal anti-inflammatory drugs for topical administration. The other

drugs Code of Automatic Telephone Exchange M02A X10 Pharmacological Pharmacokinetics At Properties use in the form of gel diclofenac rezorbirutsya slowly, deeply getting into hypodermic fatty tissue, muscle tissue, the articulate capsule and synovial fluid by direct diffusion. At long treatment or when drawing on big sites of defeat, diclofenac gradually gets into blood plasma (3-6% of the dose applied to skin). After long use of gel 3 times a day on 2.5 g (10 mg/cm2) for 3 days the stable concentration of diclofenac in blood plasma made 20-40 nmol/l, in synovial fluid-370 nmol/l, in synovial fabric-410 nmol/l. Concentration in synovial fluid rather stable, and in blood plasma quickly decrease. Diclofenac in a liver, by conjugation with glucuronic acid is metabolized. With urine about 70% of diclofenac, the rest are excreted - with a stake.
Methyl salicylate at external use is quickly absorbed, gets into hypodermic cellulose, muscle tissue and the articulate capsule and being hydrolyzed turns into anion of salicylic acid.
The pharmacodynamics
At topical administration FaniganTM Fast gel has anesthetic, anti-inflammatory and antiedematous effect. Eliminates pain and inflammation of joints, reduces morning constraint and a swelling of joints, promotes increase in volume of movements in joints.
Action FaniganTM Fast of gel is caused by components, being its part.
Diclofenac belongs to the NPVP group (non-steroidal anti-inflammatory drugs), inhibits cyclooxygenase, biosynthesis of prostaglandins – endogenous substances which play an important role in genesis of fever, inflammation and pain oppresses. Diclofenac kills pain, eliminates inflammation.
Menthol causes irritation of cold receptors. It is followed by narrowing and reduction of permeability of capillaries in the place of its drawing, feeling of a cool. Insignificant renders the local distracting and moderate anesthetizing action, menthol absorption. Menthol is metabolized in a liver and emitted with kidneys and with bile in the form of glucuronides.
Methyl salicylate represents derivative salicylic acid and possesses local irritative action. Causing irritation of receptors of skin, methyl salicylate leads to reduction of pain. Besides, methyl salicylate slows down synthesis of prostaglandins that reduces hypostasis and infiltration of the inflamed fabrics. At topical administration easily gets through the uninjured skin deep into of the inflammation center, creating high therapeutic concentrations. In the inflamed fabrics methyl salicylate is hydrolyzed and turns into anion of salicylic acid which is metabolized in a liver in degidroksibenzoyny acid and is removed by kidneys. Elimination half-life makes 2 hours.
Oil of seeds of a flax which main component is alpha linolenic acid (ethyl ether of unsaturated fatty acid) has anti-inflammatory effect, antioxidant properties, improves blood circulation in the site of application. Effect of drug begins already in a few minutes after drawing on skin, and in 20-30 min. reaches a maximum. Disappearance of the main clinical symptoms is noted usually in the first days from an initiation of treatment.
Action FaniganTM Fast of gel begins already in a few minutes after drawing on skin. In 20 - 30 min. the effect of gel reaches a maximum. The therapeutic effect is noted usually in the first days of treatment.

Topical treatment of diseases of the musculoskeletal system vospalitelno – degenerative character, followed by pain and hypostasis
- a pseudorheumatism
- an ankylosing spondylarthritis (Bekhterev's disease)
- sharp gouty, infectious, psoriasis and
posttraumatic arthritises
- rheumatic defeat of soft tissues (tendovaginitis, a bursitis, a miositis)
- an osteoarthrosis
- backbone osteochondrosis
- myalgias, neuralgia, lyumbalgiya
- injuries (bruises, sprains, muscles and sinews)
- the muscle and joints pains caused by heavy physical

the Route of administration and doses
Depending on the area of painful site 2 - 4 g of gel (strip of 4 - 8 cm) apply a thin layer to skin and easily rub 2 - 3 times a day. The average daily dose makes 10 g of gel that corresponds to 100 mg of diclofenac of sodium. It is necessary to apply drug to the uninjured skin, to avoid hit in eyes and on mucous membranes. It is impossible to apply gel on open wounds. Duration of a course of treatment should not exceed 10 days without consultation with the doctor.

Side effects
- skin rash, hypostasis and formation of blisters, papules, scales, reddenings
- xeroderma
- burning sensation or tinglings
- a skin itching, a small tortoiseshell
In isolated cases
- appearance of generalized rash
- development of hypersensitivity reaction in the form of a face edema
(Quincke's disease)
- suffocation
- a photosensitization
When drawing FaniganTM Fast of gel on extensive sites of skin is possible development of system side reactions
- heartburn, nausea, vomiting, diarrhea
- gastralgias,
- increase in activity of hepatic transaminases
- a headache, dizziness
- a hamaturia
- an acute anaphylaxis, skin rash
- anemia, thrombocytopenia, a leukopenia, an agranulocytosis
- lengthening of a bleeding time

of the Contraindication
- hypersensitivity to diclofenac and other components
of drug
- injury of epidermis, open wounds to a scope
- the asthmatic status against the background of intake of acetylsalicylic acid
- disturbance of a krovoobrazovaniye of not specified etiology
- ulcer of stomach and a 12-perstny gut in an aggravation stage
- pregnancy and the period of a lactation
- children's age up to 12 years (there is no sufficient experience about external
use of drug at this age).

Medicinal interactions
FaniganTM Fast gel can be applied along with other medicines as system interaction components of this drug with them are not revealed including with oral administration of diclofenac of sodium.
However at prolonged use FaniganTM Fast of gel in high doses it is necessary to consider that diclofenac can enhance effect of anticoagulants, glucocorticosteroids, lithium drugs and also to weaken effect of furosemide and thiazide diuretics. Drug can increase concentration of digoxin in blood plasma, reduce tolerance of other non-steroidal anti-inflammatory drugs, strengthening their ulcerogenic action on a mucous membrane of digestive tract.
At simultaneous topical administration of several drugs, the containing non-steroidal anti-inflammatory drugs, development of local irritation in the form of a small tortoiseshell, reddenings, peelings is possible.

Special instructions
At emergence of any by-effects it is necessary to perform additional examination and correction of therapy.
At patients at whom hypersensitivity reaction was observed at topical administration of acetylsalicylic acid earlier of other salicylates and other non-steroidal anti-inflammatory drugs (asthmatic attacks, skin reactions or vasomotorial rhinitises), drug is used with care, at careful weighing of all expected risk factors and advantage.
With care apply FaniganTM Fast gel in the presence in the anamnesis of a round ulcer of a stomach and duodenum, an abnormal liver function or kidneys, disturbance of a krovoobrazovaniye, a polypose of a mucous membrane of a nasal cavity.
After putting gel it is necessary to wash up hands to avoid hit of residues of drug on mucous membranes and in eyes.
Use in pediatric practice
Is not present data on safety of use of drug for children up to 12 years.
Features of influence of medicine on ability to run the vehicle or potentially dangerous mechanisms
Influence of drug on the speed of reactions at topical administration in the recommended doses is improbable.

Symptoms: a headache, a ring in ears, visual disturbances, nausea, vomiting, diarrhea, pain in epigastric area, respiratory depression, a respiratory alkalosis or a metabolic acidosis, a hyperthermia, a hypopotassemia, a hyperglycemia, increase in the ABP, a renal failure, spasms, a liver failure.
Treatment is symptomatic. Antidote is unknown.

Forms of release and packing
On 30 g or 100 g in a tuba. On 1 tuba together with the instruction for medical use in cardboard packing

to Store Storage conditions in the place protected from direct sunshine, at a temperature not above 25 °C.
Not to allow freezing!
To store out of children's reach!

2 years
not to use a period of storage after the termination of the expiration date specified on packing!

Prescription status
Without prescription

the Producer Kusum Heltker Pvt.
Ltd., JV 289 (A), Riiko Indl. Chopanki's Area, Bkhivadi (Raj.), India
to Develop
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