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Galazolin 0.05% 10 ml nasal drops




The instruction for medical use

of Galazolin® medicine

the Trade name
of Galazolin®

the International unlicensed

name Xylomethazolinum Dosage Form
of the Drop nasal 0.05%, 0.1%

of 1 ml of solution contains
active agent – xylomethazolinum a hydrochloride of 0.5 mg and 1 mg,
excipients: sorbitol, hydrophosphate sodium dodecahydrate, dihydrophosphate sodium monohydrate, dinatrium edetat, sodium chloride, a benzalkoniya chloride solution of 50%, the water purified.

The description
Transparent, colourless or almost colourless liquid

Pharmacotherapeutic group
of Antikongestanta and other nasal drugs for topical administration. Sympathomimetics.
The ATX R01 AA07 code

the Pharmacological

Pharmacokinetics Beginning properties of effect of xylomethazolinum comes in 5-10 minutes and proceeds within 10 hours.
When drawing on a mucous membrane of a nose drug causes local vasoconstriction. Usually it is not soaked up in clinically significant quantities and has no systemic action.
The pharmacodynamics
Xylomethazolinum is derivative an imidazole with sympathomimetic action.
Directly stimulates α-adrenergic receptors.
At use on a mucous membrane drug causes vasoconstriction, eliminates hypostasis and hyperaemia of a mucous membrane of a nasopharynx, reduces amount of secretion.

In complex therapy at
– acute rhinitis (cold) of virus or bacterial genesis
– an acute or chronic, recurrent inflammation of adnexal bosoms of a nose
– allergic rhinitis
– an acute inflammation of a middle ear – for the purpose of recovery of passability of the acoustical

pipe Route of administration and a dose
Intranasal use.
For hygiene one packing has to be intended only to one patient.
Âá½áº«½¿¡® 0.05%, drops the nasal
1 drop contains 0.025 mg of xylomethazolinum of a hydrochloride.
0.05% of a drop in a nose for children, aged from 2 up to 12 years:
On 1-2 drops in each nasal course, 1 or 2 times a day, each 8-10 hours.
It is not necessary to apply more than 3 times a day, in each nasal course.
The course of treatment should not exceed 3-5 days.

Âá½áº«½¿¡® 0.1%, drops the nasal
1 drop contains 0.05 mg of xylomethazolinum of a hydrochloride.
0.1% of a drop in a nose for adults and children are more senior than 12 years:
On 2-3 drops in each nasal course, each 8-10 hours.
It is not necessary to apply more than 3 times a day, in each nasal course.
The course of treatment should not exceed 3-5 days.

Side effects
– irritation and dryness of a mucous membrane of a nasopharynx, burning in a nose and a throat, sneezing
– allergic reactions (short wind, a Quincke’s edema)
Very seldom system reactions
– nausea, a headache, weakness, exhaustion, drowsiness
– a disorder of vision
– heartbeat, increase in arterial blood pressure (especially at persons with diseases of a cardiovascular system)
Is frequent
– at frequent or prolonged use the irritation or dryness mucous a nose, an atrophy mucous a nose is possible.

– hypersensitivity to drug components
– closed-angle glaucoma
– atrophic rhinitis
– surgical interventions on a meninx
– children’s age up to 2 years (for 0.05%)
– the children’s age up to 12 years (for 0.1%)

can lead Medicinal interactions At combined use with tricyclic antidepressants and MAO inhibitors to increase in arterial blood pressure. It is not necessary to take the drug during treatment by these medicines.
It is necessary to avoid simultaneous use of xylomethazolinum together with other simpatikomimetika (for example, ephedrine, pseudoephedrine) because of total action.

Special indications
of the Drop of Галазолин® 0.05% children should not appoint younger than 2 years.
At small children there can come excitement or difficulty of backfilling. If there come such symptoms, it is necessary to stop intake of medicine.
It is not necessary to use drug at patients with chronic or vasomotorial rhinitis as they note a tendency to drug use longer than 5 days. Long use of medicine can lead to secondary expansion of blood vessels and subsequently to iatrogenic rhinitis (rhinitis medicamentosa). The cause of this disease, most plausibly, oppression of release of noradrenaline from nerve terminations by means of excitement presynaptic α2-рецепторов is.
With care to apply at patients with an arterial hypertension, stenocardia and other diseases of a cardiovascular system, diabetes, a prostate hyperplasia, a hyperthyroidism, atherosclerosis, tachycardia.
It is not necessary to exceed the recommended doses, especially at children and elderly people.
In connection with the contents the chloride benzalkoniya, drug can cause irritation of a mucous membrane of a nasopharynx.
Pregnancy and the period of a lactation
Medicine should not be used at pregnancy.
There are no data concerning xylomethazolinum discharge with breast milk.
Use of medicine for women nursing demands respect for care.
Features of influence on ability to run the vehicle and potentially dangerous mechanisms
Drug does not affect ability to control of vehicles and service of moving mechanisms if apply it in the recommended doses and within a short period of time.
At prolonged use or in high doses side effects from a cardiovascular system and the central nervous system can appear.

The overdose
the Overdose at children confirmed in rare instances is characterized by such symptoms as: increase and irregularity of pulse, increase in arterial blood pressure, drowsiness, depression of breath or irregular breath, consciousness disorder. Symptomatic treatment is recommended.

The form of release and packing
On 10 ml of drug spill in polyethylene bottles with a dropper and a cover with a guarantee ring.
On 1 bottle together with the instruction for medical use in the state and Russian languages place in a pack from cardboard.

To Store storage conditions at a temperature not above 25 °C, in the place protected from light.
To store out of children’s reach!

A period of storage
4 years
the Period of storage after the first opening of a bottle – 12 weeks.
Not to apply after an expiration date.
Prescription status
Without prescription

JSC Varshavsky Producer the pharmaceutical plant Polfa,
Karolkov St. 22/24, 01-207 Warsaw, Poland

the Owner of the registration certificate
of JSC Varshavsky the pharmaceutical plant Polfa, Poland
the Address of the organization accepting in the territory of the Republic of Kazakhstan claims from consumers on quality of products (goods) of JSC Khimpharm, Shymkent, Republic of Kazakhstan, Rashidov St., 81 Phone number 7252 (561342) Fax number 7252 (561342) the E-mail address of

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