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Efizol 20s lozenges




The instruction for medical use of EFIZOL medicine the Trade name Efizol Mezhdunarodnoye the unlicensed name Is not present the Dosage form of the Tablet for resorption Structure One tablet contains active agents: dekvaliniya chloride of 0.25 mg, ascorbic acid of 30 mg excipients: glucose monohydrate, sodium saccharin, pectin, vanillin, sucrose, cocoa powder, lactoses monohydrate, magnesium stearate. The description of the Tablet of round shape, brown color with a bilateral facet and a notch on the one hand, with a smell of cocoa and vanillin, with a diameter about 13.0 mm. Pharmacotherapeutic group Drugs for treatment of diseases of a throat. Antiseptic agents. The ATX R02AA code the Pharmacological Pharmacokinetics Drug properties is quickly soaked up, distributed by means of diffusion through a liver, lungs, kidneys, output through intestines and kidneys. Long removal, with urine and a stake. The pharmacodynamics Efizol represents the combined drug with the significant local antiseptic, antibacterial and antifungal action when using for treatment of inflammatory processes of an oral cavity and a throat. Shows generally bacteriostatic (according to some information and bactericidal) action concerning a number of gram-positive and gram-negative microorganisms, including, strains, resistant to antibiotics. Drug is effective at alkaline value rn (corresponding to the oral cavity environment) and at a temperature 37ºС. Dekvaliniya chloride is a local antiseptic agent from group of kvinolin. It represents bischetvertichny kvinolin with antiseptic and bacteriostatic action. Dekvaliniya chloride shows antiseptic action – generally local, antibacterial action – mainly concerning gram-negative and gram-positive microorganisms, generally concerning pyogenic activators and strains, resistant to antibiotics (piogenic streptococci, Borrelia, etc.), antifungal action – mainly against Candida albicans, some types of Trichophyton and epidermofit. It is not active concerning Mycobacterium. The active antibacterial mechanism includes a denaturation of proteins and enzymes, by means of dissolution and a depolymerization and also glycolysis and an inactivation of dehydrogenases, at the beginning the action is reversible, however, the long contact with activators inactivates them is irreversible, disturbance of protein synthesis at the level of ribosomes, a cytolysis of a cellular membrane. Superficial active cationic action is the cornerstone of its bacteriostatic action, and it is stronger significant concerning gram-positive, than concerning gram-negative microorganisms. Ascorbic acid affects intracellular processes of oxidation and restoration, increases synthesis of specific antibacterial antitoxins and the reticuloendothelium improves functions, reduces permeability of boundary membranes, condenses and strengthens walls of capillaries and limits exudative, inflammatory and allergic reactions. Resistance to Efizol develops at long use (more than 15 – 20 days). He is effective concerning the microorganisms resistant to penicillin, streptomycin and sulfonamide. Indications – topical antiseptic treatment of easy inflammatory processes in the polostitrt and the area of a throat caused by activators, sensitive to drug: catarrhal, ulcer, fibrous ulites, aphthous stomatitises, candidiasis of a mucous membrane of an oral cavity, pharyngitises, tonsillitis, laryngitis, glossites – prevention of infections, before surgeries, in oral cavities and throats – complex treatment of infectious processes of a mouth and throat, in combination with antibiotics or sulfonamides. The route of administration and doses Appoint the Recommended doses for adults on one tablet for resorption every 2 – 3 hour (no more than 8 – 10 tablets a day). For children over 6 years on one tablet for resorption every 2-3 hour (no more than 4-6 tablets a day). The tablet is not chewed. Within half an hour after administration of drug, the patient should abstain from meal and drinks. It is recommended to continue treatment within 1-2 days after disappearance of clinical symptoms. The course of treatment should not exceed 5 – 7 days because of danger of development of dysbacteriosis. Side effects Seldom – nausea, desires to vomiting It is very rare – allergic reactions: the burning sensation and irritations, dryness in an oral cavity – dysbacteriosis (at prolonged use) Contraindications – hypersensitivity to drug components – a lactose intolerance, a glucose galactose sprue – children’s age up to 6 years Medicinal interactions At simultaneous use with kayeksalaty (drug for treatment of a hyperpotassemia) exists a likelihood of development of heavy necrotic injuries of skin and mucous membranes, in particular digestive tract. Special instructions In view of absence in drug of the anesthetizing component it should not be applied at the inflammatory processes which are followed by the significant morbidity. The concomitant use with other drugs for topical administration should be carried out carefully and after assessment of the attending physician. Despite the low content of sugar, drug, patients should use with extra care with diabetes. In the presence of clinical symptoms of spread of an infection the consultation of the doctor is necessary. At emergence of any side reactions, Efizol’s reception it is necessary to stop and appoint other treatment. Patients with a hereditary lactose intolerance should not use drug. In the absence of results of treatment with drug, it is necessary to consult with the doctor. Pregnancy and the period of a lactation Until now are not present data on safety and efficiency concerning Efizol’s impact on pregnancy. Therefore during pregnancy to take drug with caution. Efizol it is possible to apply during feeding by a breast in the recommended doses and with care. Features of influence on ability to run the vehicle or potentially dangerous mechanisms Drug does not affect ability to drive the car and potentially dangerous mechanisms. The overdose Is not present data on overdose by Efizol. A form of release and packing On 20 tablets in blister strip packaging from a transparent color film of PVH/PVDH and aluminum foil. On 1 blister strip packaging together with the instruction for medical use in the state and Russian languages place in a cardboard box. To Store storage conditions in the dry, protected from light place, at a temperature not above 25 °C. To store out of children’s reach! The period of storage Drug cannot be used 3 years after the expiration date specified on packing. Prescription status Without prescription Balkanpharma-Razgrad ABP Producer, Bulgaria the Owner of the registration certificate Balkanpharma-Dupnitsa AD, Bulgaria the Address of the organization in the territory of the Republic of Kazakhstan, the accepting claim (offer) on quality of medicines from consumers and responsible for post-registration observation of safety of medicine: Ratiopharm Kazakhstan LLP, 050059, Republic of Kazakhstan Almaty, Al-Farabi Ave. 17/1, BC Nurly-Tau body 5B, 6 floor


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