Taylol 120 mg / 100 ml 5 ml oral suspension
- $6.00
Trade name
of TAYLOL ®
the International unlicensed
name Paracetamol Dosage Form Suspension, 120 mg / 5 ml
Structure
of 5 ml of suspension contain
active agent - paracetamol of 120 mg,
excipients: aluminum magnesium silicate (talc), avitset PC 591, sodium carboxymethylcellulose 7 HOF, the sugar refined, glycerin, sorbitol of 70%, citric acid monohydrate, sodium methylparaben, sodium propylparaben, essence crimson, the water purified.
The description
Homogeneous suspension from white till light gray color with crimson aroma
Pharmacotherapeutic group
Analgetics – antipyretics other Anilides. Paracetamol
the ATX N02BE01 Code
the Pharmacological
Pharmacokinetics At properties oral administration, active ingredient is quickly and completely soaked up from digestive tract. The maximum concentration of drug in blood plasma is observed in 10 – 60 minutes. Paracetamol is widely distributed in fabrics and generally in fluid mediums of an organism, except for fatty tissue and cerebrospinal fluid. Linking with proteins makes less than 10% and slightly increases at overdose. Elimination half-life makes 1.25 - 3 hours, patients with cirrhosis have a removal period slightly more. It is metabolized in a liver by means of a microsomal and fermental system. About 85% of orally appointed dose of paracetamol are removed with urine in a free and connected look in 24 hours.
The pharmacodynamics
Paracetamol is analgetic-antipyretic. It has anesthetic and febrifugal effect, the mechanism of action is connected with inhibition of synthesis of prostaglandins, primary influence on the center of thermal control in a hypothalamus.
Indications
- fever in flu and catarrhal diseases and after vaccination
- a headache
- a toothache
- a bursitis, neuralgia, stretchings of the copular device, myalgia
- an arthralgia
the Route of administration and doses
take the Drug inside. Use for children from 2 to 3 months only on doctor's orders is possible.
Before the use the contents of a bottle should be shaken up well.
The measured spoon enclosed in packing allows to dose correctly and rationally drug.
The dose of drug depends on age and the body weight of the child.
For children the single dose of 10 - 15 mg/kg of body weight, 3-4 times a day is more senior than 3 months, the maximum daily dose makes no more than 60 mg/kg of body weight. If necessary give to the child the recommended dose each 4-6 hours, but no more than 4 doses within 24 hours.
In all other cases before Taylol's reception ® consultation of the doctor is necessary.
The body weight (kg)
Age
the Maximum Single Dose daily
mg ml mg ml
4,5-6 2-3 months
Only according to
doctor's instructions
of 6-8 3-6 months
of 4.0
96 16 384 8-10 6-12 months
5.0,120
20 480 10-13 1-2 of year
7.0,168
28 672 13-15 2-3 of year
of 9,0 216 36 864 15-21 3-6
years 10,0 240 40 960 21-29 6-9 years 14,0 336 56 1344 29-42 9-12 years
20,0 480 80 1920
Duration of reception without consultation of the doctor
- for decrease in temperature - no more than 3 days.
- for anesthesia - no more than 5 days.
Not to exceed the recommended dose.
Side effects
- nausea, an abdominal pain, vomiting
- skin rash, a small tortoiseshell, a Quincke's disease,
Stephens-Johnson Redko's syndrome
- a Quincke's edema, anaphylactic reactions
- abnormal liver functions
- renal failures
- anemia, an agranulocytosis, thrombocytopenia,
the Contraindication leukopenia
- hypersensitivity to paracetamol and other components of drug
- heavy dysfunctions baking and kidneys
- a serious illness of blood (heavy anemia, a leukopenia, a tromotsitopeniya)
- deficiency of enzyme glucose – 6 – fosfatdegidrogenaza
- diabetes
- children's age up to 2 months
Medicinal interactions
At simultaneous use of drug:
- with barbiturates, anticonvulsants, rifampicin, alcohol the risk of hepatotoxic action considerably increases
- with Metoclopramidum, increase in absorption of paracetamol
- with probenetsidy – possibly change of excretion and concentration of paracetamol in blood plasma is possible
- with coumarin derivatives perhaps development of a small prothrombinopenia
At use of Colestyraminum during the period of less than 1 hour after intake of paracetamol is possible reduction of absorption of the last.
Special instructions
it is not necessary to take the Drug along with others paracetamol the containing drugs.
Patients with hepatic, renal, cardiac and pulmonary pathology, with anemia have to be under observation of the doctor in case of drug use.
Paracetamol can result in false positive results on 5-hydroxyindolacetsilt acid in urine.
Pregnancy and a lactation
When prescribing drug it is necessary to weigh carefully expected advantage for mother and potential risk for a fruit.
Features of influence of medicine on ability to run the vehicle or potentially dangerous mechanisms
the Overdose
Symptoms does not influence: nausea, vomiting, an abdominal pain, a methemoglobinemia, cyanosis of skin and nail plates, in hard cases - excitement, and then oppression of the central nervous system, a stupor, a hypothermia, a tachypnea, a cardiopalmus, low arterial blood pressure, a circulatory unefficiency, a coma, hepatitis, jaundice, a passing azotemia, renal canalicular necrosis, a hypoglycemia, a metabolic acidosis and wet brain.
Treatment: at suspicion on overdose, the patient has to be immediately hospitalized. Symptomatic treatment.
If medicine was taken recently, it is necessary to cause vomiting, to wash out a stomach. Use as Acetylcysteinum antidote no later than 16 hours is recommended. It is not necessary to apply activated carbon and depletive as they reduce absorbability of Acetylcysteinum accepted inside. It is necessary to restore water and electrolytic balance and to carry out correction of a hypoglycemia, at its existence. In case of development of a renal and liver failure it is necessary to continue treatment before normalization of laboratory indicators. Carrying out hemodialysis.
The form of release and packing
of 100 ml of drug place in a glass dark bottle about screwing up a cover.
1 bottle together with a measured spoon and the instruction for medical use in the state and Russian languages is placed in a pack from cardboard
by
Storage conditions
to Store in the dry, protected from light place at a temperature not above 25 °C.
To store out of children's reach!
A period of storage
2 years
not to apply after an expiration date
the Period of storage after the first opening of a bottle
1 month
Prescription status
Without prescription
JSC Nobel Almatinskaya Pharmatsevticheskaya Fabrika Producer
of TAYLOL ®
the International unlicensed
name Paracetamol Dosage Form Suspension, 120 mg / 5 ml
Structure
of 5 ml of suspension contain
active agent - paracetamol of 120 mg,
excipients: aluminum magnesium silicate (talc), avitset PC 591, sodium carboxymethylcellulose 7 HOF, the sugar refined, glycerin, sorbitol of 70%, citric acid monohydrate, sodium methylparaben, sodium propylparaben, essence crimson, the water purified.
The description
Homogeneous suspension from white till light gray color with crimson aroma
Pharmacotherapeutic group
Analgetics – antipyretics other Anilides. Paracetamol
the ATX N02BE01 Code
the Pharmacological
Pharmacokinetics At properties oral administration, active ingredient is quickly and completely soaked up from digestive tract. The maximum concentration of drug in blood plasma is observed in 10 – 60 minutes. Paracetamol is widely distributed in fabrics and generally in fluid mediums of an organism, except for fatty tissue and cerebrospinal fluid. Linking with proteins makes less than 10% and slightly increases at overdose. Elimination half-life makes 1.25 - 3 hours, patients with cirrhosis have a removal period slightly more. It is metabolized in a liver by means of a microsomal and fermental system. About 85% of orally appointed dose of paracetamol are removed with urine in a free and connected look in 24 hours.
The pharmacodynamics
Paracetamol is analgetic-antipyretic. It has anesthetic and febrifugal effect, the mechanism of action is connected with inhibition of synthesis of prostaglandins, primary influence on the center of thermal control in a hypothalamus.
Indications
- fever in flu and catarrhal diseases and after vaccination
- a headache
- a toothache
- a bursitis, neuralgia, stretchings of the copular device, myalgia
- an arthralgia
the Route of administration and doses
take the Drug inside. Use for children from 2 to 3 months only on doctor's orders is possible.
Before the use the contents of a bottle should be shaken up well.
The measured spoon enclosed in packing allows to dose correctly and rationally drug.
The dose of drug depends on age and the body weight of the child.
For children the single dose of 10 - 15 mg/kg of body weight, 3-4 times a day is more senior than 3 months, the maximum daily dose makes no more than 60 mg/kg of body weight. If necessary give to the child the recommended dose each 4-6 hours, but no more than 4 doses within 24 hours.
In all other cases before Taylol's reception ® consultation of the doctor is necessary.
The body weight (kg)
Age
the Maximum Single Dose daily
mg ml mg ml
4,5-6 2-3 months
Only according to
doctor's instructions
of 6-8 3-6 months
of 4.0
96 16 384 8-10 6-12 months
5.0,120
20 480 10-13 1-2 of year
7.0,168
28 672 13-15 2-3 of year
of 9,0 216 36 864 15-21 3-6
years 10,0 240 40 960 21-29 6-9 years 14,0 336 56 1344 29-42 9-12 years
20,0 480 80 1920
Duration of reception without consultation of the doctor
- for decrease in temperature - no more than 3 days.
- for anesthesia - no more than 5 days.
Not to exceed the recommended dose.
Side effects
- nausea, an abdominal pain, vomiting
- skin rash, a small tortoiseshell, a Quincke's disease,
Stephens-Johnson Redko's syndrome
- a Quincke's edema, anaphylactic reactions
- abnormal liver functions
- renal failures
- anemia, an agranulocytosis, thrombocytopenia,
the Contraindication leukopenia
- hypersensitivity to paracetamol and other components of drug
- heavy dysfunctions baking and kidneys
- a serious illness of blood (heavy anemia, a leukopenia, a tromotsitopeniya)
- deficiency of enzyme glucose – 6 – fosfatdegidrogenaza
- diabetes
- children's age up to 2 months
Medicinal interactions
At simultaneous use of drug:
- with barbiturates, anticonvulsants, rifampicin, alcohol the risk of hepatotoxic action considerably increases
- with Metoclopramidum, increase in absorption of paracetamol
- with probenetsidy – possibly change of excretion and concentration of paracetamol in blood plasma is possible
- with coumarin derivatives perhaps development of a small prothrombinopenia
At use of Colestyraminum during the period of less than 1 hour after intake of paracetamol is possible reduction of absorption of the last.
Special instructions
it is not necessary to take the Drug along with others paracetamol the containing drugs.
Patients with hepatic, renal, cardiac and pulmonary pathology, with anemia have to be under observation of the doctor in case of drug use.
Paracetamol can result in false positive results on 5-hydroxyindolacetsilt acid in urine.
Pregnancy and a lactation
When prescribing drug it is necessary to weigh carefully expected advantage for mother and potential risk for a fruit.
Features of influence of medicine on ability to run the vehicle or potentially dangerous mechanisms
the Overdose
Symptoms does not influence: nausea, vomiting, an abdominal pain, a methemoglobinemia, cyanosis of skin and nail plates, in hard cases - excitement, and then oppression of the central nervous system, a stupor, a hypothermia, a tachypnea, a cardiopalmus, low arterial blood pressure, a circulatory unefficiency, a coma, hepatitis, jaundice, a passing azotemia, renal canalicular necrosis, a hypoglycemia, a metabolic acidosis and wet brain.
Treatment: at suspicion on overdose, the patient has to be immediately hospitalized. Symptomatic treatment.
If medicine was taken recently, it is necessary to cause vomiting, to wash out a stomach. Use as Acetylcysteinum antidote no later than 16 hours is recommended. It is not necessary to apply activated carbon and depletive as they reduce absorbability of Acetylcysteinum accepted inside. It is necessary to restore water and electrolytic balance and to carry out correction of a hypoglycemia, at its existence. In case of development of a renal and liver failure it is necessary to continue treatment before normalization of laboratory indicators. Carrying out hemodialysis.
The form of release and packing
of 100 ml of drug place in a glass dark bottle about screwing up a cover.
1 bottle together with a measured spoon and the instruction for medical use in the state and Russian languages is placed in a pack from cardboard
by
Storage conditions
to Store in the dry, protected from light place at a temperature not above 25 °C.
To store out of children's reach!
A period of storage
2 years
not to apply after an expiration date
the Period of storage after the first opening of a bottle
1 month
Prescription status
Without prescription
JSC Nobel Almatinskaya Pharmatsevticheskaya Fabrika Producer
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