Sulfatsil sodium (Albucidum-DF®) 20% 10 ml of eye drops
- $3.20
The instruction for medical use
of Albutsid-DF® medicine
the Trade name
of Albutsid-DF®
the International unlicensed
name Sulfacetamidum Natricum Dosage Form
of the Drop eye 20%, 30% 5 ml, 10 ml, 15 ml
Structure
of 1 ml of drug contains
active agent - sodium Sulfacetamidum natricum – 0.2 g, 0.3 g
excipients: Natrium thiosulfuricum, acid solution of chlorohydrogen 1 M, water for injections
the Description
Colourless or slightly yellowish color transparent liquid.
Pharmacotherapeutic group
Drugs for treatment of diseases of eyes. Antimicrobial drugs. Sulfonamides.
The ATX S01AB04 code
the Pharmacological
Pharmacokinetics At properties topical administration of Cmax of streptocides in a cornea (near
3mg/ml), moisture of an anterior chamber (about 0.5 mg/ml) and an iris (about 0.1 mg/ml) is reached in the first 30 minutes after applique. A number (less than 0.5 mg/ml) remains in eyeball tissues within 3-4 hours. At injury of an epithelium of a cornea the penetration of streptocides amplifies.
Pharmacodynamics
of Albutsid-DF®-sulfanamide antibacterial drug of a broad spectrum of activity. Has bacteriostatic effect, it is active concerning gram-positive and gram-negative cocci, Escherichia coli, Shigella spp, Vibrio cholera, Clostridium perfringens, Bacillus anthracis, Corynebacterium diphtheriae, Yersinia pestis, Chlamydia spp, Actinomyces israelii, Toxoplasma gondii. The mechanism of effect of drug is caused by competitive antagonism with paraaminobenzoic acid (PABK) and competitive oppression of a digidropteroatsintetaza that leads to disturbance of synthesis of the tetrahydrofolic acid necessary for synthesis of the purine and pirimidinovy bases. Thereof synthesis of nucleic acids (DNA and RNA) of bacterial cells is broken and their reproduction is slowed down.
Indications
- purulent helcomas
- infectious conjunctivitis
- blefarita
- prevention and treatment of gonorrheal diseases of eyes at newborns and adults
- prevention of a blennorea of newborns
- prevention of purulent complications after injuries and operations in the eyes
the Route of administration and doses
For treatment and prevention of infectious diseases of eyes:
- the adult in eyes dig in Альбуцид-DF® 30% solution on 1-2 drops 2 - 3 times a day, after disappearance of acute pyoinflammatory process dig in 1-2 drops 3 times a day
- to children of 1 year apply Альбуцид-DF® 20% solution on 1-2 drops of 4-5 times a day, after disappearance of acute pyoinflammatory process dig in on 1-2 drops 3 times a day
the Course of treatment of 5-7 days.
For prevention of a blennorea at newborns in each eye directly after the birth dig in on 2 drops 20% of solution of drug, and then on 2 drops in 2 hours.
Side effects
- reddening, gripes, dacryagogue
- an itching, the century
- short-term burning
- local allergic reactions
of the Contraindication swelled
- hypersensitivity Sulfacetamidum natricum and excipients of drug
cannot apply Medicinal interactions of Albutsid-DF® to sodium with novocaine, Dicainum, anaesthesin because of decrease in bacteriostatic effect.
Dipheninum, PASK, salicylates enhance toxicity of Albutsid-DF®, at use with anticoagulants of indirect action the specific activity of the last increases. Альбуцид-DF® at topical administration it is incompatible with silver salts.
Special instructions
It is necessary to watch that when burying the tip of a bottle dropper did not contact to other objects or surfaces. After burying it is dense to close a bottle dropper a cap!
In case of irritation of fabrics appoint solutions of smaller concentration.
Patients with hypersensitivity to furosemide, tiazidovy diuretics (Hydrochlorthiazidum), sulphonylurea derivatives (glibenclamide), karboangidraza inhibitors (Diacarbum) can have hypersensitivity to Albutsid-DF®.
Pregnancy and the period of a lactation
Use of drug at pregnancy and in the period of a lactation perhaps only in case the expected advantage for mother exceeds risk for a fruit and the baby.
Features of influence of drug on ability to run the vehicle or potentially dangerous mechanisms
When driving or potentially dangerous mechanisms to use drug with care, considering side effects.
The overdose
of Data on overdose by drug is not present.
A form of release and packing
On 5 ml, 10 ml or 15 ml of drug in the plastic bottles droppers corked by caps with control of the first opening. On one bottle together with the instruction for medical use in the state and Russian languages place in a pack cardboard.
Storage conditions
In the place protected from light, at a temperature from 15 of 0C up to 25 0C.
To store out of children's reach!
2 years
After opening of a bottle the drug use period - 10 days
not to apply a period of storage after an expiration date.
Prescription status
Without prescription
DOSFARM LLP Producer, Kazakhstan, 050034, Almaty, Chaplygin St., 3, ph.: (727) 253-03-88
The owner of the registration certificate
of DOSFARM LLP, Kazakhstan
the Address of the organization accepting in the territory of the Republic of Kazakhstan claims from consumers on quality produktsiitoo DOSFARM, Kazakhstan, 050034, Almaty, Chaplygin St., 3, ph./fax: (727) 253-07-07, 253-03-88, el. address: dospharm@dospharm.kz
of Albutsid-DF® medicine
the Trade name
of Albutsid-DF®
the International unlicensed
name Sulfacetamidum Natricum Dosage Form
of the Drop eye 20%, 30% 5 ml, 10 ml, 15 ml
Structure
of 1 ml of drug contains
active agent - sodium Sulfacetamidum natricum – 0.2 g, 0.3 g
excipients: Natrium thiosulfuricum, acid solution of chlorohydrogen 1 M, water for injections
the Description
Colourless or slightly yellowish color transparent liquid.
Pharmacotherapeutic group
Drugs for treatment of diseases of eyes. Antimicrobial drugs. Sulfonamides.
The ATX S01AB04 code
the Pharmacological
Pharmacokinetics At properties topical administration of Cmax of streptocides in a cornea (near
3mg/ml), moisture of an anterior chamber (about 0.5 mg/ml) and an iris (about 0.1 mg/ml) is reached in the first 30 minutes after applique. A number (less than 0.5 mg/ml) remains in eyeball tissues within 3-4 hours. At injury of an epithelium of a cornea the penetration of streptocides amplifies.
Pharmacodynamics
of Albutsid-DF®-sulfanamide antibacterial drug of a broad spectrum of activity. Has bacteriostatic effect, it is active concerning gram-positive and gram-negative cocci, Escherichia coli, Shigella spp, Vibrio cholera, Clostridium perfringens, Bacillus anthracis, Corynebacterium diphtheriae, Yersinia pestis, Chlamydia spp, Actinomyces israelii, Toxoplasma gondii. The mechanism of effect of drug is caused by competitive antagonism with paraaminobenzoic acid (PABK) and competitive oppression of a digidropteroatsintetaza that leads to disturbance of synthesis of the tetrahydrofolic acid necessary for synthesis of the purine and pirimidinovy bases. Thereof synthesis of nucleic acids (DNA and RNA) of bacterial cells is broken and their reproduction is slowed down.
Indications
- purulent helcomas
- infectious conjunctivitis
- blefarita
- prevention and treatment of gonorrheal diseases of eyes at newborns and adults
- prevention of a blennorea of newborns
- prevention of purulent complications after injuries and operations in the eyes
the Route of administration and doses
For treatment and prevention of infectious diseases of eyes:
- the adult in eyes dig in Альбуцид-DF® 30% solution on 1-2 drops 2 - 3 times a day, after disappearance of acute pyoinflammatory process dig in 1-2 drops 3 times a day
- to children of 1 year apply Альбуцид-DF® 20% solution on 1-2 drops of 4-5 times a day, after disappearance of acute pyoinflammatory process dig in on 1-2 drops 3 times a day
the Course of treatment of 5-7 days.
For prevention of a blennorea at newborns in each eye directly after the birth dig in on 2 drops 20% of solution of drug, and then on 2 drops in 2 hours.
Side effects
- reddening, gripes, dacryagogue
- an itching, the century
- short-term burning
- local allergic reactions
of the Contraindication swelled
- hypersensitivity Sulfacetamidum natricum and excipients of drug
cannot apply Medicinal interactions of Albutsid-DF® to sodium with novocaine, Dicainum, anaesthesin because of decrease in bacteriostatic effect.
Dipheninum, PASK, salicylates enhance toxicity of Albutsid-DF®, at use with anticoagulants of indirect action the specific activity of the last increases. Альбуцид-DF® at topical administration it is incompatible with silver salts.
Special instructions
It is necessary to watch that when burying the tip of a bottle dropper did not contact to other objects or surfaces. After burying it is dense to close a bottle dropper a cap!
In case of irritation of fabrics appoint solutions of smaller concentration.
Patients with hypersensitivity to furosemide, tiazidovy diuretics (Hydrochlorthiazidum), sulphonylurea derivatives (glibenclamide), karboangidraza inhibitors (Diacarbum) can have hypersensitivity to Albutsid-DF®.
Pregnancy and the period of a lactation
Use of drug at pregnancy and in the period of a lactation perhaps only in case the expected advantage for mother exceeds risk for a fruit and the baby.
Features of influence of drug on ability to run the vehicle or potentially dangerous mechanisms
When driving or potentially dangerous mechanisms to use drug with care, considering side effects.
The overdose
of Data on overdose by drug is not present.
A form of release and packing
On 5 ml, 10 ml or 15 ml of drug in the plastic bottles droppers corked by caps with control of the first opening. On one bottle together with the instruction for medical use in the state and Russian languages place in a pack cardboard.
Storage conditions
In the place protected from light, at a temperature from 15 of 0C up to 25 0C.
To store out of children's reach!
2 years
After opening of a bottle the drug use period - 10 days
not to apply a period of storage after an expiration date.
Prescription status
Without prescription
DOSFARM LLP Producer, Kazakhstan, 050034, Almaty, Chaplygin St., 3, ph.: (727) 253-03-88
The owner of the registration certificate
of DOSFARM LLP, Kazakhstan
the Address of the organization accepting in the territory of the Republic of Kazakhstan claims from consumers on quality produktsiitoo DOSFARM, Kazakhstan, 050034, Almaty, Chaplygin St., 3, ph./fax: (727) 253-07-07, 253-03-88, el. address: dospharm@dospharm.kz
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