Sinaflana 0.025g of 15% ointment
- $2.40
Out Of Stock
The instruction for medical use
of medicine
Synaflanum
the Trade name
Synaflanum
the International unlicensed
name Fluotsinolona acetonide
the Dosage form
Ointment for external use of 0.25 mg/g
Structure
One tuba contains
active agent: Synaflanum (a fluotsinolona acetonide) - 3.75 mg,
excipients: propylene glycol, white soft paraffin, lanolin anhydrous, ceresin.
The description
Ointment from white till yellow color.
Pharmacotherapeutic group
Glucocorticosteroids for topical treatment of diseases of skin. Glucocorticosteroids active (group III). Fluotsinolona acetonide.
The ATX D07AC04 code
the Pharmacological
Pharmacokinetics Due to properties low extent of system absorption Synaflanum at external use has no significant systemic action on an organism.
The pharmacodynamics
the Glucocorticosteroid for external use, slows down release of mediators of inflammation. At impact on skin there is prevention of a regional accumulation of neutrophils that leads to reduction of inflammatory exudate and products of cytokines, macrophage fixation, reduction of processes of infiltration and granulation. Has anti-inflammatory and antiallergic effect.
Indications
Inflammatory and allergic diseases of skin of not microbic etiology
- eczema
- contact dermatitis
- seborrheal dermatitis
- red flat deprive
- a diskoidny system lupus erythematosus
- sunblisters and burns of the I degree
- neurodermatitis
- a skin itching
- psoriasis
the Route of administration and doses
Outwardly. On previously wiped with the tampon moistened with antiseptic liquid, skin 2-4 times a day cause a small amount of drug and slightly rub. If necessary it is possible to apply an occlusive bandage, leaving it on the struck surface up to 3 - 4 days. It is not allowed to apply more than 2 g/days under a bandage. Duration of treatment is defined by clinical performance.
Side effects
- secondary infectious damages of skin
- atrophic changes of skin
- the irritation of skin (itching, burning)
Is rare
- urticaria or makulo-papular rash or aggravation of the existing changes
- under an occlusive bandage can cause resorptive action in the form of hypostases, arterial hypertension, decrease in body resistance to infections
- at use on an eyelid skin the glaucoma or a cataract
of the Contraindication
- a wound on sites of appliques
- tubercular, fungus, viral diseases of skin
- manifestation of syphilis can develop, the tuberculosis cutis, diaper rash, pink eels,
extensive psoriasis rashes (plaques), an anogenitalny itching
- the trophic ulcers of a shin connected with a varicosity,
erosive cankers of digestive tract, a wound on
sites of appliques
- a carcinoma cutaneum, a nevus, an atheroma, a melanoma, a hemangioma, a xanthoma, sarcoma
- children's age up to 2 years
- pregnancy, the lactation period
Medicinal interactions
Is compatible to antimicrobic means. Reduces activity of hypotensive, diuretic, hypoglycemic, anabolic, antiarrhythmic means.
Special instructions
not to apply without interruption more than 2 weeks. At long use on an extensive body surface the frequency of manifestation of side effects and a possibility of development of hypostases, arterial hypertension, hyperglycemia, decrease in resilience to infections increases.
At topical administration of a fluotsinolon of acetonide there can occur reduction of products of AKTG owing to oppression of a system a hypophysis adrenal glands, reduction of level of cortisol in blood and development of an iatrogenic syndrome of Cushing who passes after the treatment termination. Periodic control of function of bark of adrenal glands by definition of cortisol in blood and in urine after stimulation of adrenal glands of AKTG is shown.
In case of development of an infection in the place of use of ointment, it is necessary to carry out the corresponding antibacterial or antifungal treatment. If symptoms of an infection do not pass, it is necessary to stop use of ointment for treatment of an infection.
It is necessary to avoid use of drug on skin in the field of a century at persons with a closed-angle and open angle glaucoma and also at persons with a cataract, considering a possibility of strengthening of symptoms of a disease.
On face skin and also on skin inguinal and an underarm to apply only in cases of special need, taking in attention the increased absorption and high risk of development of side effects (teleangiectasias, dermatitis perioralis), even after short use.
It is careful to apply at already available conditions of an atrophy of hypodermic cellulose, especially at elderly people.
Features of influence of drug on ability to manage avtotrapsporty or potentially dangerous mechanisms
the Overdose
Symptoms does not influence: an itching and burning of skin in the site of application of drug, a hyperglycemia, a glucosuria, an Icenco-Cushing syndrome.
Treatment: symptomatic against the background of gradual drug withdrawal.
A form of release and packing
On 15 g in aluminum tubas. Each tuba together with the instruction for medical use in the state and Russian languages is placed in a pack from cardboard.
To Store storage conditions at a temperature from 5 With up to 15 C.
To store out of children's reach!
Not to use a period of storage of 5 years after an expiration date.
Prescription status
According to the prescription
the Open joint stock company Producer the Borisovsky plant of medications, Republic of Belarus, Minsk Region, Borisov, Chapayev St., 64,
ph. / fax +375 (177) 734043.
The owner of the registration certificate
Open joint stock company the Borisovsky plant of medications, Republic of Belarus
the Address of the organization accepting in the territory of the Republic of Kazakhstan claims from consumers on quality of products (goods)
Open joint stock company the Borisovsky plant of medications,
Republic of Belarus, Minsk Region, Borisov, Chapayev St., 64,
ph. / fax +375 (177) 734043,
the e-mail address of market@borimed.com
of medicine
Synaflanum
the Trade name
Synaflanum
the International unlicensed
name Fluotsinolona acetonide
the Dosage form
Ointment for external use of 0.25 mg/g
Structure
One tuba contains
active agent: Synaflanum (a fluotsinolona acetonide) - 3.75 mg,
excipients: propylene glycol, white soft paraffin, lanolin anhydrous, ceresin.
The description
Ointment from white till yellow color.
Pharmacotherapeutic group
Glucocorticosteroids for topical treatment of diseases of skin. Glucocorticosteroids active (group III). Fluotsinolona acetonide.
The ATX D07AC04 code
the Pharmacological
Pharmacokinetics Due to properties low extent of system absorption Synaflanum at external use has no significant systemic action on an organism.
The pharmacodynamics
the Glucocorticosteroid for external use, slows down release of mediators of inflammation. At impact on skin there is prevention of a regional accumulation of neutrophils that leads to reduction of inflammatory exudate and products of cytokines, macrophage fixation, reduction of processes of infiltration and granulation. Has anti-inflammatory and antiallergic effect.
Indications
Inflammatory and allergic diseases of skin of not microbic etiology
- eczema
- contact dermatitis
- seborrheal dermatitis
- red flat deprive
- a diskoidny system lupus erythematosus
- sunblisters and burns of the I degree
- neurodermatitis
- a skin itching
- psoriasis
the Route of administration and doses
Outwardly. On previously wiped with the tampon moistened with antiseptic liquid, skin 2-4 times a day cause a small amount of drug and slightly rub. If necessary it is possible to apply an occlusive bandage, leaving it on the struck surface up to 3 - 4 days. It is not allowed to apply more than 2 g/days under a bandage. Duration of treatment is defined by clinical performance.
Side effects
- secondary infectious damages of skin
- atrophic changes of skin
- the irritation of skin (itching, burning)
Is rare
- urticaria or makulo-papular rash or aggravation of the existing changes
- under an occlusive bandage can cause resorptive action in the form of hypostases, arterial hypertension, decrease in body resistance to infections
- at use on an eyelid skin the glaucoma or a cataract
of the Contraindication
- a wound on sites of appliques
- tubercular, fungus, viral diseases of skin
- manifestation of syphilis can develop, the tuberculosis cutis, diaper rash, pink eels,
extensive psoriasis rashes (plaques), an anogenitalny itching
- the trophic ulcers of a shin connected with a varicosity,
erosive cankers of digestive tract, a wound on
sites of appliques
- a carcinoma cutaneum, a nevus, an atheroma, a melanoma, a hemangioma, a xanthoma, sarcoma
- children's age up to 2 years
- pregnancy, the lactation period
Medicinal interactions
Is compatible to antimicrobic means. Reduces activity of hypotensive, diuretic, hypoglycemic, anabolic, antiarrhythmic means.
Special instructions
not to apply without interruption more than 2 weeks. At long use on an extensive body surface the frequency of manifestation of side effects and a possibility of development of hypostases, arterial hypertension, hyperglycemia, decrease in resilience to infections increases.
At topical administration of a fluotsinolon of acetonide there can occur reduction of products of AKTG owing to oppression of a system a hypophysis adrenal glands, reduction of level of cortisol in blood and development of an iatrogenic syndrome of Cushing who passes after the treatment termination. Periodic control of function of bark of adrenal glands by definition of cortisol in blood and in urine after stimulation of adrenal glands of AKTG is shown.
In case of development of an infection in the place of use of ointment, it is necessary to carry out the corresponding antibacterial or antifungal treatment. If symptoms of an infection do not pass, it is necessary to stop use of ointment for treatment of an infection.
It is necessary to avoid use of drug on skin in the field of a century at persons with a closed-angle and open angle glaucoma and also at persons with a cataract, considering a possibility of strengthening of symptoms of a disease.
On face skin and also on skin inguinal and an underarm to apply only in cases of special need, taking in attention the increased absorption and high risk of development of side effects (teleangiectasias, dermatitis perioralis), even after short use.
It is careful to apply at already available conditions of an atrophy of hypodermic cellulose, especially at elderly people.
Features of influence of drug on ability to manage avtotrapsporty or potentially dangerous mechanisms
the Overdose
Symptoms does not influence: an itching and burning of skin in the site of application of drug, a hyperglycemia, a glucosuria, an Icenco-Cushing syndrome.
Treatment: symptomatic against the background of gradual drug withdrawal.
A form of release and packing
On 15 g in aluminum tubas. Each tuba together with the instruction for medical use in the state and Russian languages is placed in a pack from cardboard.
To Store storage conditions at a temperature from 5 With up to 15 C.
To store out of children's reach!
Not to use a period of storage of 5 years after an expiration date.
Prescription status
According to the prescription
the Open joint stock company Producer the Borisovsky plant of medications, Republic of Belarus, Minsk Region, Borisov, Chapayev St., 64,
ph. / fax +375 (177) 734043.
The owner of the registration certificate
Open joint stock company the Borisovsky plant of medications, Republic of Belarus
the Address of the organization accepting in the territory of the Republic of Kazakhstan claims from consumers on quality of products (goods)
Open joint stock company the Borisovsky plant of medications,
Republic of Belarus, Minsk Region, Borisov, Chapayev St., 64,
ph. / fax +375 (177) 734043,
the e-mail address of market@borimed.com
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