New Fenistil® 1 mg / ml 20 ml oral drops
- $17.40
Sku:
0899b0601693
Ingredient:
Dimethindene
The instruction for medical use
of the drug FENISTIL New
(FENISTIL New)
the Trade name Fenistil New
the International unlicensed
name Dimetinden Lekarstvennaya
the Drop form for intake 1mg/ml
the Description
Colourless transparent liquid almost flavourless
Structure
of 1 ml of drug contains
active agent - a dimetinden a maleate of 1 mg
excipients: dinatrium phosphate dodecahydrate, citric acid monohydrate, benzoic acid, sodium edetat, sodium saccharin, propylene glycol, water the cleaned
Pharmacotherapeutic group
Antihistaminic drugs of systemic action. The alkylamines substituted.
The code of automatic telephone exchange R06AB03
the Pharmacological
Pharmacokinetics Quickly properties is also rather fully soaked up at intake. Bioavailability about 70%. Time of achievement of the maximum concentration of a dimetinden in blood plasma after oral administration of drops of 2 h. Communication with proteins of plasma - 90%. Well gets into fabrics, passes through a blood-brain barrier. It is metabolized in a liver by hydroxylation and a metoksilirovaniye. Elimination half-life - 6 h. It is removed with bile and urine (90% in the form of a metabolite and 10% in not changed look).
Pharmacodynamics
Antihistaminic, antiallergic and antipruritic means. H1 blocker - histamine receptors, is a competitive antagonist of the histamine released by mast cells, blocks the histamine receptors which are not occupied by him H1 in this connection it is most effective for prevention of allergic reactions of immediate type. Blocks also effect of other mediators (serotonin, bradykinin) participating in pathogenesis of allergic reactions.
Drug reduces the hyperpermeability of capillaries connected with allergic reactions.
Has weak anticholinergic effect. At administration of drug the insignificant sedation can be noted in the afternoon.
Indications
- allergic diseases (urticaria, hay fever, year-round allergic rhinitis, a Quincke's disease, food and medicinal allergy)
- a skin itching of various origin (eczema, a pruritic dermatosis, measles, rubella, chicken pox, stings of insects).
- prevention of allergic reactions during performing the hyposensibilizing therapy.
The route of administration and doses
Inside
- Children aged from 1 month up to 12 years of a dose are given in the table Frequency Rate of Appointment - 3 times a day
Age
the Single dose
the Daily dose
1 month - 1 year
of 3-10 drops
of 10-30 drops
1-3 years
of 10-15 drops
of 30-45 drops
3-12 years
of 15-20 drops
of 45-60 drops
of 20 drops = by 1 ml = in 1 mg of a dimetinden of a maleate
- Adults and children are more senior 12 years till 20-40 than drops 3 times a day
a daily dose makes 3-6 mg (60-120 drops). Course of treatment of 7-10 days.
To the patients inclined to drowsiness, it is recommended to appoint 40 drops before going to bed and 20 drops in the morning, during a breakfast.
Side effects
Often
- drowsiness (especially in an initiation of treatment)
- dryness in a mouth and a throat
it is rare
- nausea
- dizziness
- excitement
- a headache
Very seldom
- hypostases
- skin rash
- a spasm of muscles
- disturbances of functions of external respiration
of the Contraindication
- hypersensitivity to the dimetinden and other
components which are a part of drug
- closed-angle glaucoma
- a prostate hyperplasia
- children's age up to 1 month, especially premature
- the first trimester of pregnancy and a lactation.
With care
patients Should be careful when prescribing drug with bronchial asthma and chronic obstructive diseases of lungs.
Also children need care when assigning drops Fenistil New aged till 1 year as at them sedation can be followed by episodes of a night apnoea.
Medicinal interactions
are Strengthened by action of anxiolytic means and hypnotic drugs.
At the simultaneous use of ethanol leads to delay of speed of reactions.
Combined use with tricyclic antidepressants, and anticholinergic M increases risk of increase in intraocular pressure, and with inhibitors monoaminooksidayets the anticholinergic and oppressing the central nervous system action amplifies.
Special indications
of the Drop Fenistil New should not be subjected to influence of high temperature, when assigning the babies should add them to a small bottle with warm baby food just before feeding. If the child is already spoon-fed, drops can be given not divorced.
Drops have pleasant taste.
Drug is inefficient in the itching connected with a cholestasia.
Use during pregnancy
Due to the lack of any data, in the II-III trimester use is possible only under observation
of the doctor Vliyaniye on ability to run the vehicle or other potentially dangerous mechanisms
to Patients whose activity demands the increased concentration of attention and fast reactions (driving of the car, work with mechanisms) it is not recommended to take the drug.
Overdose
Symptoms: oppression of the central nervous system (CNS) and drowsiness (generally at adults), stimulation of central nervous system and anticholinergic effects (especially at children), including excitement, an ataxy, tachycardia, hallucinations, toniko-clonic spasms, a mydriasis, dryness in a mouth, rushes of blood suit, an ischuria and fever, decrease in the ABP, collapse.
Treatment: activated carbon, salt laxatives, the medicines (M) for maintenance of activity of warm and respiratory systems (analeptical should not be applied by M).
A form of release and packing
On 20 ml in a bottle of dark glass, supplied with a dropper doser from polyethylene of low density and a polypropylene cover with a control system of the first opening.
The bottle together with the instruction for use in the state and Russian languages is enclosed in a cardboard pack.
To Store storage conditions at a temperature not higher than 25 wasps.
To store out of children's reach!
The period of storage
Drug should not be used 3 years after the expiry date specified on packing.
Prescription status
Without prescription
of Proizvoditel Novartis Konsyyumer Hels SA, Switzerland (Novartis Consumer Health SA, Switzerland).
Address: rue de Letraz, p.b. 1279,1260 Nion, Switzerland (Route de l'Etraz, Case postale 1279, 1260 Nyon, Switzerland).
Representation in Russia
Novartis Konsyyumer Hels SA: 123317, Moscow, Presnenskaya Emb. 10, 14 floor
ph. (495) 969-21-65, fax 969-21-66
Representation in
Republic of Kazakhstan 050051, Almaty, Luganskogo St., 93
ph. (727) 258-12-91, fax 250-64-63
of the drug FENISTIL New
(FENISTIL New)
the Trade name Fenistil New
the International unlicensed
name Dimetinden Lekarstvennaya
the Drop form for intake 1mg/ml
the Description
Colourless transparent liquid almost flavourless
Structure
of 1 ml of drug contains
active agent - a dimetinden a maleate of 1 mg
excipients: dinatrium phosphate dodecahydrate, citric acid monohydrate, benzoic acid, sodium edetat, sodium saccharin, propylene glycol, water the cleaned
Pharmacotherapeutic group
Antihistaminic drugs of systemic action. The alkylamines substituted.
The code of automatic telephone exchange R06AB03
the Pharmacological
Pharmacokinetics Quickly properties is also rather fully soaked up at intake. Bioavailability about 70%. Time of achievement of the maximum concentration of a dimetinden in blood plasma after oral administration of drops of 2 h. Communication with proteins of plasma - 90%. Well gets into fabrics, passes through a blood-brain barrier. It is metabolized in a liver by hydroxylation and a metoksilirovaniye. Elimination half-life - 6 h. It is removed with bile and urine (90% in the form of a metabolite and 10% in not changed look).
Pharmacodynamics
Antihistaminic, antiallergic and antipruritic means. H1 blocker - histamine receptors, is a competitive antagonist of the histamine released by mast cells, blocks the histamine receptors which are not occupied by him H1 in this connection it is most effective for prevention of allergic reactions of immediate type. Blocks also effect of other mediators (serotonin, bradykinin) participating in pathogenesis of allergic reactions.
Drug reduces the hyperpermeability of capillaries connected with allergic reactions.
Has weak anticholinergic effect. At administration of drug the insignificant sedation can be noted in the afternoon.
Indications
- allergic diseases (urticaria, hay fever, year-round allergic rhinitis, a Quincke's disease, food and medicinal allergy)
- a skin itching of various origin (eczema, a pruritic dermatosis, measles, rubella, chicken pox, stings of insects).
- prevention of allergic reactions during performing the hyposensibilizing therapy.
The route of administration and doses
Inside
- Children aged from 1 month up to 12 years of a dose are given in the table Frequency Rate of Appointment - 3 times a day
Age
the Single dose
the Daily dose
1 month - 1 year
of 3-10 drops
of 10-30 drops
1-3 years
of 10-15 drops
of 30-45 drops
3-12 years
of 15-20 drops
of 45-60 drops
of 20 drops = by 1 ml = in 1 mg of a dimetinden of a maleate
- Adults and children are more senior 12 years till 20-40 than drops 3 times a day
a daily dose makes 3-6 mg (60-120 drops). Course of treatment of 7-10 days.
To the patients inclined to drowsiness, it is recommended to appoint 40 drops before going to bed and 20 drops in the morning, during a breakfast.
Side effects
Often
- drowsiness (especially in an initiation of treatment)
- dryness in a mouth and a throat
it is rare
- nausea
- dizziness
- excitement
- a headache
Very seldom
- hypostases
- skin rash
- a spasm of muscles
- disturbances of functions of external respiration
of the Contraindication
- hypersensitivity to the dimetinden and other
components which are a part of drug
- closed-angle glaucoma
- a prostate hyperplasia
- children's age up to 1 month, especially premature
- the first trimester of pregnancy and a lactation.
With care
patients Should be careful when prescribing drug with bronchial asthma and chronic obstructive diseases of lungs.
Also children need care when assigning drops Fenistil New aged till 1 year as at them sedation can be followed by episodes of a night apnoea.
Medicinal interactions
are Strengthened by action of anxiolytic means and hypnotic drugs.
At the simultaneous use of ethanol leads to delay of speed of reactions.
Combined use with tricyclic antidepressants, and anticholinergic M increases risk of increase in intraocular pressure, and with inhibitors monoaminooksidayets the anticholinergic and oppressing the central nervous system action amplifies.
Special indications
of the Drop Fenistil New should not be subjected to influence of high temperature, when assigning the babies should add them to a small bottle with warm baby food just before feeding. If the child is already spoon-fed, drops can be given not divorced.
Drops have pleasant taste.
Drug is inefficient in the itching connected with a cholestasia.
Use during pregnancy
Due to the lack of any data, in the II-III trimester use is possible only under observation
of the doctor Vliyaniye on ability to run the vehicle or other potentially dangerous mechanisms
to Patients whose activity demands the increased concentration of attention and fast reactions (driving of the car, work with mechanisms) it is not recommended to take the drug.
Overdose
Symptoms: oppression of the central nervous system (CNS) and drowsiness (generally at adults), stimulation of central nervous system and anticholinergic effects (especially at children), including excitement, an ataxy, tachycardia, hallucinations, toniko-clonic spasms, a mydriasis, dryness in a mouth, rushes of blood suit, an ischuria and fever, decrease in the ABP, collapse.
Treatment: activated carbon, salt laxatives, the medicines (M) for maintenance of activity of warm and respiratory systems (analeptical should not be applied by M).
A form of release and packing
On 20 ml in a bottle of dark glass, supplied with a dropper doser from polyethylene of low density and a polypropylene cover with a control system of the first opening.
The bottle together with the instruction for use in the state and Russian languages is enclosed in a cardboard pack.
To Store storage conditions at a temperature not higher than 25 wasps.
To store out of children's reach!
The period of storage
Drug should not be used 3 years after the expiry date specified on packing.
Prescription status
Without prescription
of Proizvoditel Novartis Konsyyumer Hels SA, Switzerland (Novartis Consumer Health SA, Switzerland).
Address: rue de Letraz, p.b. 1279,1260 Nion, Switzerland (Route de l'Etraz, Case postale 1279, 1260 Nyon, Switzerland).
Representation in Russia
Novartis Konsyyumer Hels SA: 123317, Moscow, Presnenskaya Emb. 10, 14 floor
ph. (495) 969-21-65, fax 969-21-66
Representation in
Republic of Kazakhstan 050051, Almaty, Luganskogo St., 93
ph. (727) 258-12-91, fax 250-64-63
Related Products
