Livarol 5's 400mg Vaginal suppository

The instruction for medical use of Livarol® medicine the Trade name of Livarol® the International unlicensed name Ketokonazol Lekarstvennaya a form Suppositories vaginal 400 mg Structure One suppository contains active agent – ketokonazol 400 mg, excipients: butylhydroxyanisole, basis for suppositories: a macrogoal 1500, a macrogoal 400 – before receiving a suppository weighing 3.0 g. Description Suppositories of a torpedo-shaped form, color, white, white with a yellowish or grayish or creamy shade. Suppositories have to be uniform. On a cut there have to be no impregnations. Marbling of a surface Pharmacotherapeutic group of Antiseptics and antimicrobial drugs for treatment of gynecologic diseases is allowed. Antiseptic agents and antimicrobial drugs for treatment of gynecologic diseases (excepting combinations with corticosteroids). Imidazole derivatives. Ketokonazol the ATX G01AF11 Code the Pharmacological Pharmacokinetics System Absorption properties at intravaginalny use insignificant. A pharmacodynamics of Livarol® - the antifungal means derivative of an imidazoldioksolan. Renders fungicidal and fungistasis concerning dermatophytes (Trichophyton spp., Epidermophyton floccosum, Microsporum spp.) and yeast (Candida spp., Pityrosporum spp.). It is active also concerning stafilokokk and streptococci. The mechanism of action consists in inhibition of synthesis of ergosterol of a membrane of mushrooms and disturbance of permeability of a cell wall. Indications - acute and chronic recurrent vaginal candidiasis - prevention of developing of fungal infections of a vagina at the lowered resistance of an organism and against the background of treatment by the antibacterial agents and other drugs breaking normal microflora of a vagina the Route of administration and doses Previously having exempted a suppository from planimetric packing, enter it deeply into a vagina in a dorsal decubitus on 1 suppository a day within 3-5 days depending on a course of the disease. In chronic candidiasis apply on 1 suppository of 10 days. Side effects - allergic reactions: skin rash, a small tortoiseshell - local reactions: hyperaemia and irritation of a mucous membrane of a vagina, an itching of a vagina in rare instances - hyperaemia and a phallodynia at the sexual partner Protivopokazaniya - hypersensitivity to drug components - the I trimester of pregnancy - teenage age prior to maintaining sex life Medicinal interactions At use of Livarola® negative interactions with other medicines are not known and they should not be expected since rezorbtsionny ability of a ketokonazol low. Special instructions For reduction of risk of a recurrence of a disease the simultaneous treatment of the sexual partner is recommended. It is necessary to avoid contact with products from latex (contraceptive diaphragms, condoms). It is possible to apply pregnancy and the period of a lactation of Livarol® during the II-III trimesters of pregnancy and in the period of a lactation in case the expected advantage for mother exceeds possible risk for a fruit or the child. The feature of influence of medicine on ability to run the vehicle or potentially dangerous mechanisms does not influence ability to run the vehicle or potentially dangerous mechanisms. The overdose is not revealed the Form of release and packing On 5 suppositories place in blister strip packaging from a film polyvinylchloride, laminated by polyethylene. On 1 planimetric packing together with the instruction for medical use in the state and Russian languages place in a pack from cardboard. To Store storage conditions in the dry, protected from light place at a temperature not above 25 °C. To store out of children's reach! 2 years not to use a period of storage after an expiration date. Prescription status Without prescription JSC Nizhpharm Producer, Russian Federation 603950, Nizhny Novgorod, GSP-459, Salganskaya St., 7 of ph.: (831) 278-80-88 fax: (831) 430-72-28 web website: http://www.nizhpharm.ru the Name and the country of the owner of the registration certificate of JSC Nizhpharm, the Russian Federation the Address of the organization accepting in the territory of the Republic of Kazakhstan claims from consumers on quality of products (goods) Representative office of JSC Nizhpharm 050043, Republic of Kazakhstan, Almaty, mdt. Khan-Taniri, 55b ph.: (727) 2222-100 fax: (727) 398-64-95