Bromhexine 8 mg (50 tablets)

  • $2.80
Sku: 0688ae3d00e1
Ingredient: Bromhexinum
The instruction for medical use of BROMHEXINE medicine the Trade name Bromhexine the International unlicensed name Bromhexine Dosage Form of the Tablet of 0.008 g Structure One tablet contains active agent: Bromhexine a hydrochloride – 0.008 g excipients: sucrose (white sugar), lactoses monohydrate (sugar milk), stearate calcium monohydrate, potato starch the Description of the Tablet of white color, a ploskotsilindrichesky form, with a facet Pharmacotherapeutic group Expectorant drugs. Mucolytics. Bromhexine. The ATX R05CB02 code the Pharmacological Pharmacokinetics At properties intake almost completely (99%) is soaked up in digestive tract within 30 minutes. Bioavailability - low (effect of primary passing through a liver). Gets through placentary and hematoencephalic barriers. In a liver is exposed to demethylation and oxidation, it is metabolized to pharmacological active Ambroxol. Elimination half-life - 15 hours (owing to slow return diffusion from fabrics). It is removed by kidneys. In chronic kidney disease the removal of metabolites is broken. At repeated use can kumulirovat. The pharmacodynamics Mucolytic (sekretolitichesky) means, has expectorant and weak antibechic effect. Reduces viscosity of a phlegm (depolymerizes mucoprotein and mukopolisakharidny fibers, increases a serous component of a bronchial secret), activates a ciliary epithelium, increases volume and improves otkhozhdeny phlegms. Stimulates production of the endogenous surfactant providing stability of alveolar cells in the course of breath. The effect is shown in 2-5 days from an initiation of treatment. Indications - sekretolitichesky therapy in acute and chronic diseases of the bronchial tubes and lungs which are followed by difficult separated phlegm - before - and the postoperative period (sanitation of a bronchial tree in the preoperative period and when carrying out medical and diagnostic intra bronchial manipulations, prevention of an accumulation in bronchial tubes of a dense viscous phlegm after operation) the Route of administration and doses Inside to adults and children are more senior than 14 years – 8-16 mg 3-4 times a day. To children at the age of 6-14 years – 8 mg 3 times a day. If necessary the dose can be increased by the adult up to 16 mg 4 times a day. The patient with a renal failure appoint smaller doses or increase an interval between administrations of drug. Side effects Sometimes - fervescence - hypersensitivity reactions (skin rash, a Quincke's disease, disorders of breath, an itching, urticaria) - nausea, an abdominal pain, vomiting, diarrhea Very seldom - exacerbation of a peptic ulcer of a stomach and a 12-perstny gut - increase in activity of 'hepatic' transaminases - anaphylactic reactions, including an acute anaphylaxis - development of heavy skin reactions, such as Stephens-Johnson's syndrome and scalded skin syndrome At reactions of hypersensitivity, anaphylactic reaction or emergence of any unusual changes on skin and mucous membranes it is necessary to stop immediately intake of Bromhexine and to see a doctor. Contraindications - hypersensitivity to Bromhexine or to one of other components of drug - intolerance of a galactose or fructose, a glucose galactose sprue, insufficiency of invertase-isomaltase - a round ulcer of a stomach - pregnancy (I trimester) and the lactation period - children's age up to 6 years With care - a renal and/or liver failure - the diseases of bronchial tubes which are followed by an excessive accumulation of a secret - in the anamnesis - gastric bleeding - the pregnancy period (II and III trimester) do not appoint Medicinal interactions along with the medicines suppressing the tussive center (including codeine) as it complicates an otkhozhdeniye of the diluted phlegm (accumulation of a bronchial secret in airways). It is incompatible with alkaline solutions. Bromhexine promotes penetration of antibiotics (amoxicillin, erythromycin, cefalexin, Oxytetracyclinum), sulfanamide medicines in a bronchial secret in the first 4-5 days of antimicrobial therapy. Special instructions At treatment it is necessary to accept enough liquid that increases expectorant effect of Bromhexine. At children the treatment should be combined with postural drenazhy or the vibration massage of a thorax facilitating removal of a secret from bronchial tubes. Pregnancy and the period of a lactation In the I trimester of pregnancy drug is contraindicated. During pregnancy (II and III trimester) Bromhexine is appointed only when the expected advantage for mother exceeds potential risk for a fruit. Bromhexine gets through a placental barrier therefore in need of use of drug in the period of a lactation the breastfeeding needs to be stopped. Features of influence of medicine on ability to run the vehicle or potentially dangerous mechanisms during administration of drug perhaps insignificant easing of attention owing to what it is necessary to refrain from control of vehicles and occupations other potentially dangerous types of activity demanding the increased concentration of attention and speed of psychomotor reactions. Overdose Symptoms: dispepsichesky disorders, including nausea, vomiting, diarrhea. Treatment: artificial vomiting, gastric lavage (in the first 1-2 h after reception). A form of release and packing On 10 tablets in blister strip packaging from a film of the polyvinylchloride and printing aluminum foil varnished or papers with a polyethylene covering. 5 blister strip packagings with the instruction for medical use in the state and Russian languages place in a pack from cardboard. To Store storage conditions in the dry, protected from light place at a temperature not higher than 25 wasps. To store out of children's reach! A period of storage 3 years not to use after an expiration date Prescription status Without ProizvoditelOAO's prescription Biosintez, Russian Federation 440033, Penza, Druzhby St., 4, ph. / fax (8412) 57-72-49, e-mail: the Name and the country of the owner registration udostovereniyaoao Biosintez, the Russian Federation the Address of the organization accepting in the territory of the Republic of Kazakhstan claims from consumers on quality of products (goods) of JSC Biosintez, Russian Federation 440033, Penza, Druzhby St., 4, ph. / fax (8412) 57-72-49, e-mail:
Write a review
Related Products
OZ GNCLS (Ukraine)
Tablets cough-OZ 50 mg (10 tablets)
Kusum Healthcare (India)
Mukeks 30 mg (20 tablets)
Dr. Theiss (Germany)
Salvia chamomile and honey 24's lozenge tablet
Natur Produkt (Netherlands)
MaksiGrippin 10s 5g powder for oral solution honey-lemon
Natur Produkt (Netherlands)
Eucalyptus M 24's lozenges
Pharmacy 2010 (Kazakhstan)
Lugol with glycerin solution 25 g
Unique Pharmaceutical Labs (India)
IOM doctor with strawberry pastilles 20s
Medana (Poland)
Ibufen D 100 mg / 120 ml 5 ml oral suspension