Acyclovir 3% ophthalmic ointment 5 grams.

  • $8.10
Sku: a8f12f6c72cd
Ingredient: Acyclovir
The instruction
for medical use

of ACYCLOVIR medicine

the Trade name

the International unlicensed

name Acyclovir Dosage Form
oculentum of 3%

of 1 g of ointment contains
active agent - acyclovir – 0.03 g,
excipient - vaseline to 1 g

the Description
Ointment white or white with a yellowish shade, or yellow color

the Pharmacotherapeutic group
Antiviral means for topical administration
the Code of automatic telephone exchange S01AD03

the Pharmacological

Pharmacokinetics Acyclovir properties easily gets through an epithelium of a cornea and creates therapeutic concentration in intraocular liquid. Now there are no methods of definition of acyclovir in blood at its use in the form of oculentum. Acyclovir at external use is defined only in urine, and in insignificant quantity. This concentration has no therapeutic value.
A pharmacodynamics
Acyclovir - antiviral (anti-herpetic) means – a synthetic analog of a nucleoside of thymidine.
In the infected cells containing a virus thymidinekinase there is a phosphorylation and transformation in atsiklovirmonofosfat. Under the influence of guanylate cyclase atsiklovirmonofosfat it will be transformed to diphosphate and under the influence of several cellular enzymes – to triphosphate. The sharp selectivity of action and hypotoxicity for the person are caused by lack of necessary enzyme for formation of the atsiklovirtrifosfat in intact cells of a macroorganism.
Acyclovir triphosphate, being built in the deoxyribonucleic acid (DNA) synthesized by a virus, blocks reproduction of a virus. The specificity and very high selectivity of action are also caused by its primary accumulation in the cells affected with a herpes virus.
Acyclovir is highly active concerning the Herpes simplex 1 and 2 virus of types, the virus causing chicken pox and shingles (Varicella zoster), Epstein-Burra's virus (types of concentration (MPK) of acyclovir). It is moderately active concerning a cytomegalovirus (CMV).
In herpes prevents formation of new elements of rash, reduces the probability of skin dissimination and visceral complications, accelerates formation of crusts, reduces pain in sharp the surrounding herpes.

- the herpetic keratitis caused by the Herpes simplex 1 or 2 virus

of the Route of administration types and doses
To adults and children oculentum in the form of a strip 1 cm long is put in the lower conjunctival sac of 5 times a day (each 4 h) before healing.
Treatment is continued within 3 days after healing.

Side effects
- the easy burning (which is taking place over time)
- a dot superficial keratopathy (does not demand the termination of treatment and disappears without consequences)
- conjunctivitis
- blepharitis
Allergic reactions: seldom - skin rash, an itching, it is very rare: reactions of immediate hypersensitivity (including a Quincke's disease)

- hypersensitivity to acyclovir or a valatsiklovir

Medicinal interactions
Use together with immunostimulators enhances effect of acyclovir.

The special
instructions Efficiency of Treatment that will be higher, than earlier it is begun (at the first symptoms of an infection).
During treatment by oculentum of acyclovir the condition of the immune system of an organism matters. Patients with reduced immunity against the background of topical administration of ointment of acyclovir should appoint system administration of drug, just as in case of a heavy and recurrent course of a herpes infection.
Pregnancy and a lactation
Use of drug at pregnancy is possible in case the potential advantage for mother exceeds risk for a fruit.
Drug is found out in breast milk after receipt in a system blood stream of mother therefore for treatment the breastfeeding should be stopped.
Features of influence of medicine on ability to run the vehicle or potentially dangerous mechanisms
After drug use perhaps temporary decrease in clearness of visual perception, and before its restoration it is not recommended to drive the car and to be engaged in the types of activity requiring special attention and reaction.

The overdose
Overdose is possible at accidental ingestion.
Symptoms: headache, neurologic disturbances, short wind, nausea, vomiting, diarrhea, renal failure, lethargy, spasms, coma.
Treatment: maintenance of the vital functions, hemodialysis.

Form of release and packing
On 5 g place in tubas aluminum.
Each tuba with the instruction for medical use in the state and Russian languages is placed in a pack from cardboard.

To Store storage conditions at a temperature from 15 °C to 25 °C
to Store out of children's reach!

3 years
to Use a period of storage within 30 days after opening.
Not to use after an expiration date.

Prescription status
Without prescription

Russia JSC Sintez Producer, 640008, Kurgan, Konstitutsii Avenue, 7.
ph./fax (3522) 48-16-89

The address of the organization accepting in the territory of the Republic of Kazakhstan claims from consumers on quality of products
000100, Republic of Kazakhstan, Kostanay region, Kostanay, Uralskaya St., 14
ph. 714 228 01 79
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