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Vizallergol 2.5 ml of 0.2% eye drops

$20.00

8c3039753942

Description

The instruction for medical use of Vizallergol Torgovoye medicine a name Vizallergol Mezhdunarodnoye the unlicensed name Olopatadin Lekarstvennaya the Drop form eye 0.2% 2.5 ml Structure of 1 ml contains active agent – an olopatadin a hydrochloride of 2.22 mg (it is equivalent to an olopatadin of 2 mg), excipients: a benzalkoniya chloride, K-29/32 povidone, sodium hydrophosphate anhydrous, sodium chloride, dinatrium edetat, sodium hydroxide, acid chlorohydrogen, water for injections. The description Transparent from colourless before yellow coloring solution. Pharmacotherapeutic group Drugs for treatment of diseases of eyes. Decongestants and antiallergic drugs. Olopatadin. ATX S01GX09 code Pharmacological Pharmacokinetics At properties topical administration system absorption low. Cmax of an olopatadin in blood plasma is reached during 2 h and makes from 0.5 ng/ml to 1.3 ng/ml. T1/2 in plasma makes 3 h. 60–70% are removed mainly by kidneys, – in not changed look. The pharmacodynamics Olopatadin has antiallergic effect, H1 receptors are selection inhibitor histamine and also inhibit release of mediators of inflammation from mast cells. Does not render effect on α-adrenergic, dopamine, muskarinovy type 1 and 2 and also serotoninovy receptors. Indications – for prevention of the itching of eyes connected with allergic conjunctivitis. A route of administration and the mode of dosing For topical administration in eyes. Drug is not intended for injections and intake. The drug Vizallergol is dug in on 1 drop in the lower conjunctival sac of the affected eye (eyes) once a day. Duration of treatment is established by the doctor. When burying solution it is not necessary to touch with a pipette tip eyes or any other surface to avoid solution pollution. It is necessary to close densely a cover after drug use. Side effects In 10% of cases – the symptoms similar to symptoms of cold and pharyngitis In some cases (less than 5%) – illegibility of sight, burning or pricking, conjunctivitis, xerophthalmus, feeling of a foreign body, hyperaemia, hypersensitivity, a keratitis, the century, pain and naggers Prochiye – an asthenia, a dorsodynia, a grippopodobny syndrome, a headache, strengthening of cough, infection, nausea, rhinitis, sinusitis and a food faddism of the Contraindication – hypersensitivity to drug components swelled – children’s age up to 8 years the Medicinal interactions of Researches of interaction of an olopatadin with other medicines were not carried out. The researches in vitro showed what olopatadin does not inhibit the metabolic reactions connected with isoenzymes 1A2, 2C8, 2C9, 2C19, 2D6, 2E1 and 3A4 of R-450 cytochrome. These results show the low probability that olopatadin will enter metabolic reactions at simultaneous use with other active agents. If necessary it can be applied in a combination with other local ophthalmologic drugs. In this case the interval between their use has to make not less than 5 min. Special instructions of Olopatadin the hydrochloride is local antiallergic / antihistamine, at topical administration system absorption low. At emergence of the undesirable phenomena or signs of hypersensitivity it is necessary to stop drug use. Olopatadin a hydrochloride of 0.2% should not be applied to removal of the redness of eyes caused by carrying contact lenses. In this case the patient should refuse carrying contact lenses. The chloride which is contained in drug a benzalkoniya can be absorbed by contact lenses. Before burying drug of a lens it is necessary to remove and establish back not earlier than in 20 min. after burying drug. Benzalkoniya the chloride which is widely applied as preservative in ophthalmologic products according to a number of researches is the reason of a dot keratopathy and/or toxic ulcer keratopathy. As drug the benzalkoniya contains chloride, careful monitoring of a condition of eyes of patients with a syndrome of a dry eye at frequent or long use is necessary and also at patients with the damaged cornea. Dose adjustment of drug at patients with pathologies of kidneys and a liver and also is not required from elderly people. Pregnancy and the period of a lactation of Sufficient experience on use of drug during pregnancy and in the period of a lactation are not present. Use of drug at pregnancy is possible in case the expected medical effect exceeds potential risk for a fruit. The drug Vizallergol should not be used when breastfeeding. In case of need drug uses, breastfeeding should be stopped. The feature of influence of medicine on ability to run the vehicle or potentially dangerous mechanisms is not recommended to drive the car and to be engaged in other types of activity demanding the increased concentration of attention and speed of psychomotor reaction right after burying (development of illegibility of visual perception is possible). In this case, it is necessary to wait some time before recovery of sight. Overdose Symptoms: at topical administration the overdose is improbable. Treatment: at hit in eyes of excess amount of drug it is recommended to wash out eyes plentiful amount of warm water. The form of release and packing On 2.5 ml of drug place in plastic bottles with a capacity of 5 ml, with a plastic tip and the screwing-up cap with control of the first opening. On 1 bottle together with the instruction for medical use in the state and Russian languages place in a pack cardboard. To Store storage conditions at a temperature from 2C to 25 °C. Not to freeze. To store out of children’s reach! A period of storage 2 years the use Period after opening of a bottle of 28 days. Not to apply after expiry date. Prescription status According to the prescription of Proizvoditel SENTISS FARM PVT. LTD. 212/D-1, Greene Park, New Delhi, India At the plant: Villidzh Khera Nikhla, Tekhsil Nalagarkh, Region of Solan, Himachal Pradesh 174,101, India Owner of the registration certificate of SENTISS FARMA of PVT. LTD., India

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