Oksivin-DF 0,025% Eye Drops 10 ml.

The instruction for medical use of Oksivin-DF® medicine the Trade name of Oksivin-DF® the International unlicensed name Oxymetazoline Dosage Form of the Drop eye 0.025% 10 ml Structure of 1 ml of drug contains active agent - oxymetazoline a hydrochloride of 0.25 mg, excipients: a benzalkoniya chloride (in the form of 10% of solution), sodium chloride, dihydrophosphate sodium a dihydrate, phosphate dinatrium dodecahydrate, water for injections the Description Transparent colourless or slightly yellowish solution Pharmacotherapeutic group Sense bodys. Ophthalmologic drugs. Decongestants and antiallergenic drugs. The sympathomimetics applied as decongestants. Oxymetazoline the ATX S01GA04 Code the Pharmacological Pharmacokinetics At properties topical administration oxymetazoline in a small amount is soaked up in a system blood stream therefore its concentration in blood plasma is insignificant. Effect of drug is shown in 15 minutes after use and 6-8 hours proceed. Drug is metabolized only in moderate degree and generally removed from an organism in an invariable view with urine and a stake. The pharmacodynamics Oksimetazolin is alpha adrenomimetikom from group of derivatives of imidazoline. Stimulates α1-адренорецепторы. At instillation in a conjunctival sac (a cavity between a back surface a century and the front surface of an eyeball) reduces puffiness, hyperaemia and exudative manifestations from a conjunctiva (external cover of an eye). Indications - allergic conjunctivitis - conjunctivitis of a non-infectious etiology (smoke, dust, impact of wind and the sun, the chlorinated water, artificial lighting) - developments of stagnation and a chemosis the Route of administration and doses Locally. To adults and children 8 years are more senior: in a conjunctival sac on 1-2 drops of drug in each eye 3-4 times a day. Course of treatment no more than 3 days. Before use of drug to remove contact lenses and to wait not less than 15 minutes after burying drug. It is necessary to watch that when burying the tip of a bottle dropper did not contact to other objects or surfaces. After burying it is dense to close a bottle dropper a cap! Side effects Usually drug is well transferred. Not often - the irritation of a conjunctiva and surrounding fabrics - a mydriasis - accommodation paresis - retraction of a century Seldom - are possible irites - concern - a sleep disorder - fatigue - headaches Very seldom - dizziness - nausea - hypertensia - Contraindication tachycardia - hypersensitivity to drug components - closed-angle glaucoma - arrhythmias - arterial hypertension - chronic heart failure - chronic kidney disease - the profound atherosclerosis - diabetes - a thyrotoxicosis, a hyperthyroidism - a prostate hyperplasia - a concomitant use of inhibitors of a monoaminooxidase and the period up to 14 days after the end of their use - a pheochromocytoma - a porphyria - children's age up to 8 years - pregnancy and the period of a lactation Medicinal interactions Drug slows down absorption of mestnoanesteziruyushchy means and prolongs their effect. At use of Oksivina-DF® with other vasoconstrictors (irrespective of a method of administration) perhaps mutual strengthening of side effects. Co-administration of inhibitors of a monoaminooxidase (including the period within 14 days after their cancellation) and tricyclic antidepressants can lead to increase in arterial blood pressure. Special instructions it is not necessary to exceed independently recommended doses and to use drug more than 3 days. To apply with care in the coronary heart disease (CHD). As the chloride which is contained in drug a benzalkoniya decolours soft contact lenses, it is necessary to refrain during treatment for carrying soft contact lenses! Features of influence of medicine on ability to run vehicles or potentially dangerous mechanisms Considering side effects of Oksivina-DF® it is necessary to observe care when driving or potentially dangerous mechanisms. Overdose Symptoms: irritation and dryness of a conjunctiva, mydriasis, increase in intraocular pressure. Treatment: to wash eyes with flowing water, further - symptomatic therapy. A form of release and packing On 10 ml of drug in the plastic bottles droppers corked by caps with control of the first opening or on 10 ml in the plastic bottles droppers corked by caps. On each bottle paste the label. On one bottle together with the instruction for medical use in the state and Russian languages place in a pack cardboard. To Store storage conditions in the place protected from light, at a temperature not over 25 ºС. To store out of children's reach! A period of storage 3 years the Period of use of drug after the first opening of a bottle - 28 days. Not to apply after an expiration date. Prescription status Without prescription DOSFARM LLP Producer, Kazakhstan, 050034, Almaty, Chaplygin St., 3, ph.: (727) 253-03-88 The holder of the registration certificate of DOSFARM LLP, Kazakhstan, 050034, Almaty, Chaplygin St., 3 the Name, the address and a contact information (phone, the fax, e-mail) of the organization in the territory of the Republic of Kazakhstan, the accepting claim (offer) on quality of medicines from consumers and responsible for post-registration observation of safety of medicine: DOSFARM LLP, Republic of Kazakhstan, Almaty, Chaplygin St., 3, ph./fax: (727) 253-03-88, el. address: dospharm@dospharm.kz