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Description
Compound
One sachet (sachet) 16 g contains
- active ingredient – aluminum phosphate gel 20% – 10.40 g (corresponds to 2.08 g of aluminum phosphate),
- excipients: calcium sulfate dihydrate, pectin, agar-agar 800, orange flavor, potassium sorbate, sorbitol solution 70%, purified water
Pharmacological properties
Pharmacokinetics
The drug is practically not absorbed from the gastrointestinal tract. The absorption of aluminum phosphate is about 0.087%. Absorbed aluminum is completely excreted from the body by the kidneys. Does not bind to food phosphates.
Pharmacodynamics
It has an acid-neutralizing, enveloping, adsorbing effect. Reduces the proteolytic activity of pepsin. Does not cause alkalization of gastric juice, keeping the acidity of gastric contents at the physiological level. Does not lead to secondary hypersecretion of hydrochloric acid. Forms a protective layer on the mucous membrane of the gastrointestinal tract. Promotes the removal of toxins, gases and microorganisms throughout the digestive tract, normalizes the passage of contents through the intestines.
Indications for use
– peptic ulcer of the stomach and duodenum
– gastritis with normal or increased secretory function
– diaphragmatic hernia
– reflux esophagitis
– non-ulcer dyspepsia syndrome
– functional diarrhea
– gastric and intestinal disorders caused by intoxication, taking medications, irritating substances (acids, alkalis), alcohol
– for preventive purposes to reduce the absorption of radioactive elements
Dosage and administration
Inside, 1-2 sachets 2-3 times a day. The regimen depends on the nature of the disease:
Gastroesophageal reflux, diaphragmatic hernia – immediately after meals and at night.
Peptic ulcer of the stomach and duodenum – 1-2 hours after eating and immediately if pain occurs.
Gastritis, dyspepsia – before meals.
Functional diseases of the colon – in the morning on an empty stomach and at night. If in the interval between doses of Phosphalugel the pain resumes, repeat the drug.
Recommendations for use
| Thoroughly knead the contents of the sachet between your fingers to obtain a homogeneous gel.
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| Holding the pouch upright, cut or tear off the corner where indicated.
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| Squeeze the gel with your fingers through the opening in the sachet.
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The gel is taken in pure form or diluted before taking in half a glass of water. |
Side effects
Rarely
– constipation (mainly in elderly patients, bedridden patients)
– allergic reactions (Quincke’s edema, urticaria)
Contraindications
– hypersensitivity to any component of the drug
– Severe renal dysfunction
– for patients with hereditary fructose intolerance
– Alzheimer’s disease
Drug Interactions
Due to the absorption and enveloping effect, Phosphalugel may reduce the effectiveness of certain drugs.
Antibiotics of the tetracycline group, iron preparations, cardiac glycosides should be taken no earlier than 2 hours after taking Phosphalugel, as their absorption slows down.
Special instructions
Do not take the drug for a long time without a doctor’s prescription.
Use with caution in cirrhosis of the liver and severe heart failure. In elderly patients and patients with impaired renal function, when using Phosphalugel at recommended doses, an increase in the concentration of aluminum in the blood serum is possible.
With constipation, which occasionally occurs when taking Phosphalugel, it is recommended to increase the amount of daily water consumed.
The drug can be used by patients suffering from diabetes mellitus.
The drug can be used prophylactically to reduce the absorption of radioactive elements.
The use of the drug Phosphalugel does not affect the results of the X-ray study.
Pregnancy and lactation
Not recommended due to lack of data.
Features of influence on the ability to drive a vehicle and potentially dangerous mechanisms
Does not affect.
Overdose
Symptoms : inhibition of motility of the gastrointestinal tract.
Treatment: the appointment of laxatives, symptomatic therapy.
Storage conditions
Store at a temperature not exceeding 25 0C.
Keep out of the reach of children!
Shelf life – 3 years
Do not use after the expiration date.
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