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Kanefron H (60 coated tablets)




The instruction for medical use of Kanefron® medicine H the Trade name of Kanefron® of N the International unlicensed name Is not present the Dosage form of the Tablet, coated Structure One tablet contains active agents: Centaury of a grass of 18 mg of Lyubistok medicinal roots of 18 mg of Rosemary of leaves of 18 mg excipients: tablet kernel: lactoses monohydrate, magnesium stearate, starch corn, K 25 povidone, silicon dioxide colloidal anhydrous structure of a cover of a tablet: calcium carbonate, castor oil, glucose syrup, gland (III) oxide red (E 172), starch corn, dextrin, wax montanic glycolic, K 30 povidone, Riboflavinum (E 101), shellac, sucrose, talc, titan dioxide (E 171). The description of the Tablet, coated, round shape, with a biconvex and smooth surface of orange color. Pharmacotherapeutic group Urinogenital system and sex hormones. Urological drugs. Other drugs for treatment of urological diseases. The ATX G04BX code the Pharmacological Pharmacokinetics Measurement properties of three markers in plasma of animals in preclinical trials was shown by dozo-proportional influence after oral administration of high doses of Kanefron® of N in toxicity researches at repeated introduction. Besides, at repeated introductions of accumulation it was not observed. A pharmacodynamics In various clinical trials the use of Kanefron® of N led to fast decrease in number of the complaints connected with inflammatory diseases of efferent uric pathways. The results received during these clinical trials demonstrate anti-inflammatory, spasmolytic, anti-nociceptive and antibacterial effects of Kanefron® of N. of Kanefron® of N showed antioxidant and also anti-inflammatory activity, lowered physiologically relevant concentration of reactive forms of oxygen and nitrogen, interfered with release of E2 prostaglandin and cytokines and also interfered with products of leukotrienes. Канефрон® the N reduced adhesion of uropatogenny bacteria to epithelial cells of a bladder. Individual Kanefron® components H have antibacterial activity and have small diuretic effect which maintains antibacterial activity as bacteria are washed away from uric ways. Data on the cancerogenic potential of Kanefron® of N are absent. Indications – acute and chronic cystitis – as an additional tool of treatment in specific therapy of pyelonephritis, glomerulonephritis, interstitial nephrite – prevention of formation of urinary stones – after operational removal of urinary stones the Route of administration and doses Patients the Single dose the Daily dose Adults and teenagers from 12 years 2 tablets of 6 tablets Children of school age (6 years are more senior) School age children 1 tablet 3 tablets After easing of sharpness of a disease should continue treatment within 2-4 weeks. Accept a single dose in the morning, during the lunchtime and in the evening, without chewing, with enough liquid. Duration of treatment is defined by the attending physician. At use of drug the plentiful consumption of liquid is recommended. Side effects are possible: – allergic reactions to drug components (for example, rash, an itching) – gastrointestinal disorders (for example, nausea, vomiting, diarrhea) At the first signs of allergic reaction it is necessary to stop administration of drug. Contraindications – the increased individual sensitivity to any components of drug, to other plants of family of umbrella (Umbelliferae) (for example, an anise, fennel) or to p-propenyl anisole (component of essential oils). – ulcer of stomach and duodenum during an acute period – children’s age up to 6 years – hypostases owing to dysfunction of heart or kidneys and/or if limited consumption of liquid was recommended the doctor. Medicinal interactions Are unknown. The combination with antibacterial medicines is possible. Special instructions At long high temperature, spasms, presence of blood in urine, disturbances of urination and a sharp ischuria it is necessary to consult immediately with the doctor. Канефрон® the N contains glucose, sucrose and lactose. Patients with hereditary intolerance of fructose, a galactose, deficiency of lactase or insufficiency of invertase-isomaltase or malabsorption of a glucose/galactose should not use this drug. Use for patients with diabetes One tablet, coated, contains about 0.020 grain units (GU). Pregnancy and a lactation of Kanefron® of N it is necessary to accept during pregnancy only on doctor’s orders, after assessment by the doctor of a ratio of advantage risk of its use and strictly following instructions on its use. Medicine should not be accepted to women during breastfeeding. Features of influence of medicine on ability to run the vehicle or potentially dangerous mechanisms Drug does not affect ability to run transport and to work with potentially dangerous mechanisms. Overdose About cases of overdose it was not reported. Symptomatic treatment. A form of release and packing On 20 tablets, coated, in blister strip packaging from aluminum foil and a film polyvinylchloride / polyvinyldichloride (PVH/PVDH). On the 3rd blister strip packaging together with the instruction for medical use in the state and Russian languages place in a pack from cardboard. To Store storage conditions in original packing, at a temperature not above 25 °C. To store out of children’s reach! 4 years not to use a period of storage after the expiration date specified on packing. Prescription status Without prescription the Producer Bionorika XIE, D-92308 of Noymarkt / Germany the Holder of the registration certificate Bionorika XIE, D-92308 of Noymarkt / Germany the Name, the address and a contact information (phone, the fax, e-mail) of the organization in the territory of the Republic of Kazakhstan, the accepting claim (offer) on quality of medicines from consumers and responsible for post-registration observation of safety of medicine of Bionorika KAZ LLP of Almaty, Central post office, p.o. box No. 200, ph. 250-93-99


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