The instruction for medical use of Hydroten Torgovoye medicine a name Hydroten Mezhdunarodnoye the unlicensed name Dekspantenol Lekarstvennaya a form Cream for external use of 5% Structure of 1 grams of drug contains active agent: dekspantenol 50.00 mg excipients: a chlorhexidina a hydrochloride, PEG-6 polyethyleneglycol stearate, ethylene glycol palmitostearat and polietilengltkol PEG-32 stearate mix (TEFOSE 63), 2 octyldodecyl myristate (MOD), jojoba oil, stearyl alcohol, vaseline, oil mineral, EDTA dinatrium, fragrance lavender, the water purified. The description Uniform cream of soft smooth consistence, with a characteristic smell, white or whitish color, without visible inclusions. Pharmacotherapeutic group Drugs for treatment of wounds and ulcers. Drugs for hyper scarring treatment. Other drugs for hyper scarring treatment. The ATX D03AX code the Pharmacological Dekspantenol Pharmacokinetics properties is quickly soaked up in skin. Dekspantenol turns into pantothenic acid (B5 vitamin) and unites with an endogenous part of this vitamin. In blood pantothenic acid contacts proteins of plasma (b-globulins and albumine), is removed in an invariable look – 60-70% with urine, the rest through a GIT. Chlorhexidin when drawing on skin is practically not soaked up. At oral administration chlorhexidin it is almost completely allocated with a stake. The pharmacodynamics Dekspantenol is active component of Hydroten, quickly turns in cells into pantothenic acid (B5 vitamin). Pantothenic acid – a component of essential coenzyme A. In the form of acetyl coenzyme A plays an important role in metabolism of a cell and improves regeneration of skin and mucous membranes. Dekspantenol easily extends at topical administration. Chlorhexidina a hydrochloride one of the most active and well transferable local antiseptic agents with bactericidal activity concerning the gram-positive bacteria, especially sensitive strains of golden staphylococcus and microorganisms involved in skin infections. It also destroys gram-negative bacteria and mushrooms (sorts Candida). Indications – wounds of any genesis when there is a risk of an infection: grazes, scratches, cuts, cracks, burns, ulcers, dermatitis – treatment of chronic wounds (decubituses, ulcers standing and others) – in a skin infection, for example, again infected eczema, neurodermatitis – treatment of nipple cracks at nursing mothers the Route of administration and doses Cream put with a thin layer one or several times a day, as required on previously cleaned wound or the inflamed sites of skin and slightly rub. If necessary it is possible to use a bandage. Duration of treatment depends on indications and efficiency of therapy. Side effect Is rare – allergic reactions (urticaria, an itching). Contraindications – the increased individual sensitivity to drug components – at damage of extensive sites of skin – at perforation of a tympanic membrane Medicinal interactions interaction Cases with other drugs are unknown. Chlorhexidina the hydrochloride is not compatible to the detergents containing anion group (saponins, sodium lauryl sulfate, sodium carboxymethylcellulose) and also to soap. Special instructions It is necessary to avoid contact with eyes, ears and mucous membranes. Dekspantenol together with chlorhexidiny (Hydroten, cream) should not be applied to treatment of skin irritations which can / should not be infected (for example, a sunblister). In such cases use of cream or lotion with dekspantenoly is recommended. Pregnancy and the period of a lactation Cream can be used during pregnancy and during breastfeeding (before feeding it is necessary to wash away drug). Not to apply at damage of more extensive sites of skin during pregnancy and breastfeeding. Features of influence of medicine on ability to run transport or potentially dangerous mechanisms the Overdose Symptoms does not influence: irritation of skin in rare instances (at very frequent use on the same site of skin). Treatment. To cancel drug use. Symptomatic therapy. The form of release and packing On 30 g of drug place in tubas aluminum with a plastic cap with the punch for a membrane. On 1 tuba together with the instruction for medical use in the state and Russian languages place in a pack from cardboard Storage conditions to Store at a temperature not above 25 °C, in the dry, protected from light place. To store out of children’s reach! 2 years not to use a period of storage after the expiration date specified on packing Prescription status Without prescription Republic of Kazakhstan JSC Nobel Almatinskaya Pharmatsevticheskaya Fabrika Producer Almaty, Shevchenko St. 162 E the Address of the organization accepting in the territory of the Republic of Kazakhstan claims from consumers on quality of products (goods): JSC Nobel Almatinskaya Pharmatsevticheskaya Fabrika Republic of Kazakhstan Almaty, Shevchenko St. 162 E. Phone number: (+7 727) 275-03-05
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