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Geksoral 0.2 ml of 40% aerosol




The instruction for medical use of Hexoral Torgovoye medicine a name Hexoral Mezhdunarodnoye the unlicensed name Hexetidin Lekarstvennaya a form Aerosol of 0.2% Structure of 100 ml of drug contain active agent – Hexetidinum of 0.2 g excipients: polysorbate 80, citric acid monohydrate, sodium saccharin, left menthol, an eucalyptus prutovidny leaves oil, calcium sodium edetat, ethanol of 96%, sodium hydroxide, water purified, nitrogen. The description Transparent colourless liquid with a menthol smell Pharmacotherapeutic group Antimicrobial drugs for topical treatment of diseases of an oral cavity. The ATX A01AB12 code the Pharmacological Pharmacokinetics Hexetidin properties adgezirutsya very well on a mucous membrane and is practically not soaked up. After single use of active ingredient its traces find on mucous gums during 65 h. In plaques on teeth the active concentration remain during 10–14 h after use. A pharmacodynamics Antimicrobial effect of the drug Hexoral is connected with suppression of oxidizing reactions of metabolism of bacteria (antagonist of thiamine). Drug possesses antibacterial and antifungal action, in particular concerning gram-positive bacteria and mushrooms of the sort Candida, also to render effect at treatment of infections, vyzvannykhpseudomonas to aeruginosa or Proteus. In concentration of 100 mg/ml drug suppresses the majority of strains of bacteria. Development of stability was not observed. Hexetidinum has weak anesthetic effect on a mucous membrane. Indications as symptomatic means. Symptomatic treatment in inflammatory infectious diseases of an oral cavity and throat: – tonsillitis, a tonsillitis (including Plauta-Vincent’s tonsillitis, a tonsillitis of side rollers), pharyngitis, an ulitis, stomatitis, a glossitis, periodontosis, – fungus diseases, – prevention of infectious complications before surgeries on an oral cavity and a throat and in injuries, including prevention of infection of alveoluses after extraction of tooth – hygiene of an oral cavity, including and for elimination of an unpleasant smell from a mouth the Route of administration and doses Locally. Children from 4 to 6 years: use of drug is possible under medical supervision when drawing by means of a cotton plug. Adults and children are more senior than 6 years: process affected areas at breath holding, on 1 injection within 1–2 seconds 2 times a day. Hexetidinum adgezirutsya on a mucous membrane and thanks to it gives lasting effect. In this regard drug should be used after a meal. The general recommendations about introduction spray Drug in an oral cavity or a throat. By means of aerosol it is possible to process easily and quickly affected areas. It is necessary to perform the following operations: · to put on a nozzle spray an aerosol can, · to direct the end of a nozzle spray to an affected area of an oral cavity or throat, · during administration of drug the bottle should be held constantly in vertical position, as shown in the drawing, · to administer necessary amount of the drug, pressing on a nozzle spray head within 1–2 seconds, not to breathe at administration of aerosol. Duration of treatment is defined by the doctor. Side effects Very seldom – reactions of hypersensitivity (including a small tortoiseshell), a Quincke’s disease, full or partial loss of flavoring feelings, cough, the short wind caused by emergence of reaction of hypersensitivity dryness in a mouth, a dysphagy, nausea, increase in sialadens, vomiting, reactions in the site of application (including irritation of a mucous membrane of a mouth and throat, burning sensation, paresthesia of an oral cavity, change of coloring of language, change of coloring of teeth, inflammation, formation of bubbles and ulcerations). If any side effects specified in the instruction are aggravated or you noticed other side effects, it is recommended to see a doctor. Contraindications – hypersensitivity to any of drug components – erosive deskvamoznye damages of a mucous membrane of an oral cavity – patients with the bronchial asthma or other respiratory diseases accompanied with the significant hypersensitivity – existence in the anamnesis of febrile spasms, epilepsies (in connection with contents as a part of excipients of terpenes – left menthol, an eucalyptus of prutovidny oil of leaves) – children’s age up to 4 years Medicinal interactions Data are absent. Special instructions long-term treatment as it can lead to disturbance of normal microflora of an oral cavity and throat is not shown. This drug as auxiliary components contains terpenic derivatives which are capable to lower an epileptogenic threshold. In case of reception of excessively high doses there is a risk of development of the neurologic phenomena like convulsive attacks at chest babies and children. It is necessary to observe the recommended dosage and duration of treatment. Drug contains the insignificant amount of ethanol (alcohol) which is not exceeding 100 mg on a dose. Pregnancy and a lactation Drug is not recommended for use when breastfeeding in force: · lack of dynamic data on receipt of terpenic derivatives in milk, · and also owing to potential neurologic toxicity of these derivatives concerning chest babies. Features of influence of drug on ability to run motor transport or potentially dangerous mechanisms the Overdose does not influence It is improbable that Hexetidinum can have toxic effect at use according to the instruction for use of medicine. The ingestion of a large amount of the drug containing ethanol can lead to emergence of signs/symptoms of a drunkenness. At any cases of overdose immediately consult with the doctor. Symptomatic treatment, as in a drunkenness. Gastric lavage is necessary within 2 hours after ingestion of an excess dose. Form of release and packing Aerosol of 0.2%. On 40 ml of drug place in an aluminum aerosol container. On one container complete with a nozzle spray and the instruction for medical use in the state and Russian languages place in a pack cardboard. To Store storage conditions at a temperature not above 25 °C. To store out of children’s reach. A period of storage 3 years not to use drug after the expiration date specified on packing. Contents of an aerosol container should be used within 6 months after the first use. Prescription status Without prescription the Producer Famar Orlean, avenue de Consir, 5, 45071 of Orlean Sedex 2, France the Holder of the registration certificate of LLC Johnson & Johnson, Russian Federation, 121614, Moscow, Krylatskaya St., 17, building 2 the Address of the organization accepting claims from consumers on quality of products (goods) and responsible for post-registration observation of safety of medicine in the territory of the Republic of Kazakhstan LLC Johnson & Johnson Branch in Republic of Kazakhstan 050040, Republic of Kazakhstan, Almaty, Timiryazev St., 42, pavilion 23-A


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