for medical use
of Espumizan® medicine
the Trade name
the International unlicensed
name Simetikon Lekarstvennaya a form
of the Capsule, 40 mg
One capsule contains
active agent – the simetikon (consisting of dimethyl silicone (PDMS) and silicon of dioxide) of 40 mg
structure of a cover of the capsule:
methylparahydroxybenzoate, gelatin, glycerin of 85%, dye yellow-orange S, 85% (E 110), dye of quinolinic yellow, 70% (E 104)
Almost round uniform soft gelatin capsules of yellow color with a seam and a smooth surface, capsule contents – viscous colourless liquid can also be slightly muddy. Diameter of capsules – about 5 mm.
Drugs for treatment of functional disorders of intestines. Other drugs for treatment of functional disorders of intestines. Silicones.
The code of automatic telephone exchange A03AX13
Pharmacokinetics Simetikon properties is not soaked up after intake and after passing through digestive tract is output in not changed look again.
as active ingredient contains In the capsule drug Espumizan® simetikon — stable surface-active dimethyl silicone. It changes surface intention of the vials of gas which are in food gruel and in slime of a digestive tract therefore they break up. The gases which are released at the same time can then be soaked up by a gut wall and also be removed under the influence of an intestines vermicular movement.
Action of a simetikon has purely physical character, he does not participate in chemical changes and is inert in the pharmacological and physiological relations.
– for symptomatic treatment of the complaints from digestive tract caused by the raised accumulation of gases (in an abdominal distension, a meteorism)
– as supportive application for diagnostic tests in an abdominal cavity (radiological and ultrasonic researches).
A route of administration and doses
At complaints from digestive tract (caused, for example, by the meteorism raised by an accumulation of gases):
2 capsules (≤ 80 mg of a simetikon)
from 3 to 4 times a day
Espumizan® of the capsule can also be accepted after operations.
Эспумизан® capsules accept in time or after a meal and also if it is necessary, before going to bed.
Duration of therapeutic use depends on dynamics of complaints.
In need of Espumizan® of the capsule it is possible to accept during longer span.
Note: At repeated emergence and/or more long complaints from digestive tract it is necessary to perform clinical examination.
As supportive application for diagnostic tests in an abdominal cavity (radiological and ultrasonic researches):
One day before carrying out a research
in the Morning in day of carrying out a research
2 capsules 3 times a day
(≤ the general dose of 240 mg of a simetikon)
(≤ 80 mg of a simetikon)
– allergic reactions to dye yellow-orange S (E 110)
– hypersensitivity reactions including the slowed-down type on methylparahydroxybenzoate (E 218)
of the Contraindication
– hypersensitivity to active ingredient to a simetikon, dye yellow orange of S (E 110), to methylparahydroxybenzoate (E 218) or any other Espumizana® components of capsules
– children’s and teenage age up to 18 years
So far cases are unknown.
The special indications
of the Complaint caused by the increased gas generation can be sign of more serious problems from digestive tract.
Symptoms can be shown as follows:
sense of pressure or overflow,
In case of emergence and/or long presence of similar complaints you need to see a doctor. The doctor, having performed examination, will define whether there is a basic disease demanding other treatment.
Use during pregnancy and a lactation
Thanks to the mechanism of action of a simetikon and its low absorbability from digestive tract, negative effect after reception of Espumizana® of capsules during pregnancy and in the period of a lactation is not expected.
There are no clinical data on use of Espumizana® of capsules for pregnant women and the feeding women.
Features of influence of medicine on ability to run the vehicle and potentially dangerous mechanisms
About cases of overdose does not influence it was not reported.
As in the chemical and physiological relation simetikon it is completely inert, intoxication is almost excluded. Эспумизан® capsules it is transferred asymptomatically also in large numbers.
A form of release and packing
On 25 capsules in blister strip packaging from a film of polyvinylchloride and aluminum foil.
On 1, 2 or 4 planimetric packs together with the instruction for medical use in the state and Russian languages put in a pack cardboard
to Store at a temperature not above 30 °C.
To store out of children’s reach!
not to use a period of storage after the storage expiration!
Proizvoditel Berlin-Hemi AG (Menarini Group) Gliniker Weg 125 12489 Berlin, Germany
the Owner of the registration certificate
Berlin-Hemi AG (Menarini Group) Gliniker Weg 125 12489 Berlin,
Germaniya Upakovshchik Berlin-Hemi AG (Menarini Group) Gliniker Weg 125 12489 Berlin, Germany
the Address of the organization accepting in the territory of the Republic of Kazakhstan claims from consumers on quality of products (goods): Representative office of JSC Berlin-Hemi AG in RKNomer of phone number: +7 727 2446183, 2446184, 2446185 Fax number: +7 727 2446180 E-mail address: Kazakhstan@berlin-chemie.com