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Erythromycin Efor 10000g 10g ophthalmic ointment. in a tube




The instruction for medical use of ERYTHROMYCIN medicine the Trade name Erythromycin the International unlicensed name Erythromycin Dosage Form oculentum of 10000 PIECES in 1 g Structure of 100 g of ointment is contained: active agent – erythromycin in terms of 100% substance of 1.00 g, excipients: anhydrous lanolin, sodium metabisulphite, vaseline. The description Ointment from yellowish till fulvous color. Pharmacotherapeutic group Drugs for treatment of diseases of eyes. Antimicrobial drugs. Antibiotics. Erythromycin. The ATX S01AA17 code the Pharmacological Pharmacokinetics Is Soaked Up properties in a cornea and watery moisture of an eye. At topical administration the therapeutic concentration of erythromycin in eye tissues, system absorption low is reached. At injury of an epithelium of a cornea the effective concentration of erythromycin in moisture of an anterior chamber is reached in 30 min. after applique. A pharmacodynamics the Bacteriostatic antibiotic from group of macroleads. At topical administration has antibacterial effect. Reversibly contacts 50S a subunit of ribosomes that breaks formation of peptide bonds between molecules of amino acids and blocks protein synthesis of microorganisms (does not influence synthesis of nucleic acids). At use in high doses depending on a type of the activator can show bactericidal action. Chlamydia trachomatis is effective concerning the sensitive microorganisms causing superficial eye infections of a conjunctiva of a cornea including concerning Neisseria gonorrhoeae. Indications – bacterial blepharitis – bacterial conjunctivitis – trachoma – a bacterial keratitis the Route of administration and doses Locally. The strip of ointment 0.5-1 cm long is put for a lower eyelid by 3 times a day, and at treatment of trachoma of 4-5 times a day. Duration of treatment depends on a form and disease severity, but should not exceed 14 days. In trachoma the treatment should be combined with opening of follicles. When subsiding inflammatory process, drug is used by 2-3 times a day. Duration of a course of treatment of trachoma should not exceed 3 months. Side effects development of allergic reactions and irritant action (reddening, an itching) is possible. At prolonged use the consecutive infection caused by microorganisms, resistant to erythromycin, hyperaemia, irritation of a mucous membrane of an eye, illegibility of visual perception can develop. Contraindications – hypersensitivity to drug components – heavy abnormal liver functions and kidneys – jaundice in the anamnesis. Medicinal interactions It is incompatible with lincomycin, clindamycin and chloramphenicol (antagonism). Reduces bactericidal action beta laktamnykh antibiotics (penicillin, cephalosporins, karbopenema). Pharmaceutical it is incompatible with aminoglycosides. When using with corticosteroids leads to increase in their effect. At simultaneous use of dosage forms of erythromycin for external use with the abrasive substances leading to excessive irritation of skin and also with the means causing peeling of skin the cumulative irritating or drying-up effect is possible. At simultaneous use of dosage forms of erythromycin for external use with the abrasive substances leading to excessive irritation of skin, and also with the means causing peeling of skin the cumulative irritating or drying-up effect is possible. Special instructions With care: advanced age, renal failure and liver. Children At prevention of an ophthalmia of newborns it is not necessary to wash away erythromycin oculentum from an eye. At children whose mothers have clinically apparent gonorrhea erythromycin as ophthalmologic means is used along with aqueous solution of penicillin G for parenteral use. After opening of a tuba to use within 6 weeks. Pregnancy, the period of a lactation of Sufficient experience on use of drug during pregnancy and feeding by a breast is not present. Use of Erythromycin for treatment of pregnant women appointed by the attending physician is possible if the expected medical effect exceeds risk of development of possible side effects. In need of use in the period of a lactation it is necessary to resolve an issue of the breastfeeding termination. Use of antibacterial agent can be followed by emergence of organisms, resistant to erythromycin, including mushrooms, in case of organisms, resistant to erythromycin, use of antibacterial agent has to be stopped and the appropriate measures are taken. Avoid pollution of a tip of a tuba mucous an eye, fingers or from other source. The feature of influence of drug on ability to run motor transport or potentially dangerous mechanisms does not influence. Overdose Data on overdose of drug are absent. Form of release and packing oculentum. On 10 g in tubas aluminum. The tuba together with the instruction for medical use in the state and Russian languages is placed in a pack from cardboard. To Store storage conditions in the place protected from light at a temperature not above 15 °C. To store out of children’s reach! Period of storage 3 years. To store after the first opening of packing no more than 6 weeks. Not to apply after an expiration date. Prescription status According to the prescription the Russia JSC Tatkhimpharmpreparaty manufacturing Organization, 420091, Kazan, Belomorskaya St., 260 Ph.: (843) 571-85-58, fax: (843) 571-85-38 E-mai1: the Name and the country of the holder of the registration certificate of JSC Tatkhimpharmpreparaty, Russia the Name, the address and a contact information of the organization in the territory of the Republic of Kazakhstan, the accepting claim (offer) on quality of medicines from consumers and responsible for post-registration observation of safety of medicine: MegaPharmPlyus LLP Republic of Kazakhstan, YuKO, 160019, Shymkent, Abaysky district, residential district Kyzyl heat, Karasu St., 30 Ph.: 8 (7252) 45-31-23, fax: 8 (7252) 45-31-56 E-mail:

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