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Buscopan 10 mg (20 tablets) p.s.o




The instruction for use of medicine for experts
of Buskopan

the Trade name
of Buskopan

the International unlicensed name
of Hyoscine butylbromide

the Dosage form
of the Tablet, covered with a sugar cover

1 tablet covered with a sugar cover contains
active agent – hyoscine – N – of butylbromide, 10 mg
excipients: double-base phosphate of calcium, corn starch, soluble starch, colloidal silicon dioxide, tartaric acid, stearic/palmitic acid.
Cover: polyvinylpirrolidone, sucrose, talc, Arabian gum, titan dioxide, polyethyleneglycol 6000, karnaubsky wax, white wax.

The description
the White biconvex tablets covered with a sugar cover.

M-holinoblokator group. The automatic telephone exchange code of A03BB01

Buskopan properties has spasmolytic effect on smooth muscles of internals (gastrointestinal, bilious and urinogenital paths), reduces secretion of digestive glands. Being quarternary ammonium derivatives, hyoscine – N – butylbromide does not get through a blood-brain barrier therefore anticholinergic influence on central nervous system is absent.

– spastic conditions of a gastrointestinal, bilious and urinogenital path (renal colic, bilious colic, intestinal colic, cholecystitis, a pylorospasm)
– spastic dyskinesia of biliary tract and a gall bladder
– a peptic ulcer of a stomach and duodenum in an aggravation phase (as a part of complex therapy)
– algodismenoreya

the Route of administration and doses
If it is not appointed somehow differently, the following mode of dosing is recommended:
Adults and children are more senior than 6 years: 3-5 times a day on 1-2 tablets,
the Tablet covered with a sugar cover it is necessary to swallow entirely and to wash down with enough liquid.

Side effects
– dryness in a mouth, dryness of integuments
– tachycardia
– drowsiness
– accommodation paresis
– is possible an ischuria which is usually not expressed and is allowed independently
– to hypersensitivity reaction with skin manifestations
– emergence of the complicated breath

of the Contraindication
– hypersensitivity to hyoscine – N – to butylbromide or any other component of drug
– closed-angle glaucoma
– a myasthenia gravis
– megacolon

Medicinal interactions
Buskopan can strengthen anticholinergic effect of tricyclic antidepressants, antihistaminic drugs, quinidine, an amantadin and Disopyramidum.
Co-administration of Buskopan and antagonists of a dopamine, for example, of Metoclopramidum, leads to weakening of effect of both drugs on digestive tract.
Buskopan can strengthen the tachycardia caused by the means stimulating beta adrenoceptors.

Special instructions
Because of possible risk of development of anticholinergic complications, it is necessary to be careful use of drug for patients with closed-angle glaucoma, It is necessary to appoint with care drug in the following clinical situations: suspicion on intestinal impassability (including a pyloric stenosis), obstruction of urinary tract (including prostate adenoma), tendency to tachyarrhythmias (including a ciliary tachyarrhythmia).
Pregnancy and a lactation
Are not present any data on negative influence of drug on pregnancy. However, as well as when using other drugs, it is necessary to appoint with care drug during pregnancy, especially in the first trimester.
Safety of drug in the period of a lactation is not proved yet. However, about cases of undesirable effects at newborns it is not reported.

So far cases of overdose of BUSKOPANOM are not described therefore the following symptoms can be connected with its pharmacological effect.
Possible anticholinergic symptoms: an ischuria, dryness in a mouth, erubescence, tachycardia, oppression of motility of digestive tract and also passing disorders of vision.
Symptoms of overdose of BUSKOPANA are stopped by cholinomimetics. To patients with glaucoma locally appoint pilocarpine in the form of eye drops. If necessary cholinomimetics enter systemically, for example,
neostigmin 0.5-2.5 mg intramusculary or intravenously. Cardiovascular complications treat according to usual therapeutic rules. In paralysis of respiratory muscles the intubation, artificial ventilation of the lungs is shown. In case of an ischuria catheterize a bladder. Maintenance therapy is carried out.

The form of release and packing
of the Tablet of 10 mg covered with a sugar cover.
In packing of 20 tablets.

Storage conditions
At a temperature not higher than 25 wasps.
To store out of children’s reach!

Not to use an expiration date of 5 years after the expiration date specified on packing.

Prescription status
Without prescription

the Producer Boehringer Ingelcheim France, France

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