The instruction for medical use
the Trade name
the International unlicensed
name Bisacodyl Dosage Form
Suppositories rectal 0.01 g
One suppository contains
active agent – bisacodyl – 0.01 g,
excipients: silicon dioxide of colloidal 0.01 g, fat
of firm 1.28 g.
Suppositories of white or cream color, cigar-shaped form. On a cut there have to be no impregnations, existence of an air core or funneled deepening is allowed.
Contact laxative drugs. Bisacodyl
the ATX A06AB02 Code
Pharmacokinetics Bisacodyl properties – means of contact action. In the minimum degree it is absorbed from intestines (up to 5% of bisacodyl). After conjugation in a liver Bisacodyl joins in enterohepatic blood circulation, is partially emitted with kidneys.
At use of rectal candles before going to bed laxative action comes in 8-12 hours.
Bisacodyl – depletive.
Bisacodyl increases secretion of slime in a large intestine, accelerates and strengthens a vermicular movement of a large intestine, has laxative effect.
Bisacodyl is pro-medicine. At rectal use in the alkaline environment there is a hydrolysis to formation of the substance rendering irritant action on mucous a large intestine.
Effect of Bisacodyl is caused by direct stimulation of nerve terminations of a mucous membrane of a large intestine, stimulates removal of water and electrolytes in a gleam of intestines and blocks their reabsorption.
the Route of administration and doses
Previously having released constipations of various genesis I shine from planimetric packing by means of scissors, it is entered deeply into a rectum: to adults and teenagers at the age of 15-18 years – on 1-2 candles a day. To children at the age of 8-14 years – on 1 candle a day. It is not necessary to apply Bisacodyl more than 5-7 days.
– intestinal colic, diarrhea (dehydration, muscle weakness, spasms, a lowering of arterial pressure), abdominal pains, a meteorism
– allergic reactions
of the Contraindication
– hypersensitivity to drug components
– intestinal impassability, acute inflammatory diseases of abdominal organs, peritonitis
– bleedings from digestive tract, a metrorrhagia
– an acute proctitis and hemorrhoids
– children’s age up to 8 years
At simultaneous use of cardiac glycosides their action amplifies because of deficiency of potassium.
instructions Apply with care to patients with a liver/renal failure.
Pregnancy and a lactation
it is not necessary to use drug during pregnancy because of possible penetration of active ingredient through a placental barrier. Bisacodyl does not get into mother’s milk. With care appoint in the period of a lactation.
Features of influence of medicine on ability to run the vehicle or potentially dangerous mechanisms
it is not revealed
Symptoms: it is shown by diarrhea with loss of a large amount of liquid and electrolytes, muscle weakness and spasms.
Treatment: take measures for elimination of dehydration and/or restoration of ionic balance.
A form of release and packing
On 5 suppositories in blister strip packaging from a polyvinylchloride film. On the 2nd blister strip packagings together with the instruction for medical use in the state and Russian languages place in a pack from cardboard.
To Store storage conditions at a temperature not above 25 °C.
To store out of children’s reach!
not to use a period of storage after an expiration date.
JSC Lekkhim-Kharkiv Producer 61115, Ukraine, Kharkiv, 17th Partsjezda St., 36.
The address of the organization accepting in the territory of the Republic of Kazakhstan claims from consumers on quality of products (goods):
050000, Republic of Kazakhstan
Almaty, st. Mussorgsky, 2a
ph. +007 (7272) 71 48 12, 71 48 13