of BETAGIST 8
of BETAGIST 16
of BETAGIST 24
the International unlicensed
name Betagistin Lekarstvennaya a form
of the Tablet of 8 mg, 16 mg, 24 mg
One tablet contains
active agent – a betagistin dihydrochloride of 8 mg, 16 mg or 24 mg,
excipients: cellulose microcrystalline PH 112, Mannitolum, anhydrous citric acid, silicon dioxide colloidal (Aerosil 200), stearic acid, talc.
Round tablets of white color, with a plain surface on one party and risky on another (for a dosage of 8 mg).
Round tablets of white color, biconvex, with risky on one party (for a dosage of 16 mg).
Oblong tablets of white color with risky on one party (for a dosage of 24 mg)
of Means for elimination of dizziness.
The code of automatic telephone exchange N07CA01
Pharmacokinetics Later properties of intake of a betagistin a hydrochloride is absorbed quickly and completely.
Linking with proteins of plasma low. Betagistina a hydrochloride is quickly metabolized in a liver in an inactive main metabolite, 2-pyridylacetic acid and in dimethyl-betagistin.
It is brought to 90% through kidneys in the form of the main metabolite.
Betagistin is a synthetic analog of a histamine. Affects histamine H1 and H3 receptors of an inner ear and vestibular nuclei of central nervous system. Improves microcirculation and permeability of capillaries of an inner ear, increases a blood stream in basilar arteries, normalizes endolymph pressure in a labyrinth and a snail.
BETAGIST renders dose-dependent overwhelming effect on generation of peaks in neurons of lateral and medial vestibular nuclei.
BETAGIST accelerates restoration of vestibular function after unilateral neurectomy, facilitating and accelerating processes of the central vestibular compensation. This effect is carried out thanks to antagonism of H3 receptors and characterized by the raising regulation of emission and exchange of a histamine. In a combination, all these properties carry out therapeutic effect of BETAGISTA in Menyer’s disease and vestibular dizziness.
– Menyer’s disease/syndrome
– the symptomatic treatment of vestibular dizziness of various genesis which is followed by nausea and vomiting
– sonitus, the progressing decrease in hearing (as a part of complex therapy)
the Route of administration and doses
the Recommended initial dose makes 8-16 mg a day. The main medical doses – 24-48 mg a day.
The maximum single dose makes 24 mg.
The maximum daily dose makes 48 mg which is divided into 2-3 receptions.
Tablets on 8 mg
of the Tablet on 16 mg
of the Tablet on 24 mg
on 1-2 tablet
3 times a day
on 1/2-1 tablet
3 times a day
on 1 tablet
2 times a day
the Stable therapeutic effect occurs after two weeks of treatment and can increase within several months of treatment. Long-term treatment. Duration of administration of drug is selected individually. Duration of administration of drug is defined by the attending physician.
Often (from ³1/100 to
– a headache, drowsiness
– feeling of heat
– pain in anticardium, heartburn, nausea, vomiting
– rash, urticaria, an itching, a Quincke’s edema, anaphylactic reactions
of the Contraindication
– hypersensitivity to a betagistin to a hydrochloride and/or to any of drug components
– a pheochromocytoma
– pregnancy and the period of a lactation
– the children’s and teenage age up to 18 years
As betagistin is an analog of a histamine, simultaneous use of H1 of antagonists can cause mutual easing of effect of active agents.
With care to use drug at patients from a peptic ulcer of a stomach and a duodenum in the anamnesis, bronchial asthma.
Features of influence of medicine on ability of driving or potentially dangerous mechanisms
Due to the emergence of side effect in the form of fatigue the ability to reaction can be reduced that breaks ability to driving of the car and ability to operate the vehicles.
Symptoms: dryness in a mouth, nausea, vomiting, dyspepsia, an ataxy, face reddening, dizziness, the increased heartbeat, a bronchial spasm and hypostasis and after reception of very high doses can also happen convulsions.
Treatment – symptomatic (gastric lavage, use of activated carbon).
The form of release and packing
On 10 tablets place in blister strip packaging from a formatura of aluminum and printing aluminum foil.
On 3 or 6 planimetric packs together with the instruction for medical use in the state and Russian languages place in a pack cardboard with the hologram of firm – producer.
To Store storage conditions at a temperature not over 25 ºС, in the dry, protected from light place.
To store out of children’s reach!
not to apply a period of storage after a period of storage.
According to the prescription
Republic of Kazakhstan JSC Nobel Almatinskaya Pharmatsevticheskaya Fabrika Producer,
Almaty, Shevchenko St. 162 E.
Owner of the registration certificate
of JSC Nobel Almatinskaya Pharmatsevticheskaya Fabrika
Republic of Kazakhstan