VALTREX® (Valaciclovir) 500 mg, 10 tablets

What is VALTREX® (Valaciclovir)?

VALTREX® is an antiviral medication used to manage infections caused by herpes viruses. It contains valaciclovir 500 mg, which your body quickly transforms into aciclovir – an active agent that blocks virus replication. This action helps reduce symptoms and speeds up recovery. VALTREX® is commonly prescribed for treating herpes zoster (shingles), genital herpes, and cold sores, while also helping prevent recurrences and transmission to others.

Each package includes 10 film-coated tablets, and the product should be stored at temperatures not exceeding 30°C (86°F).

How does VALTREX® work in the body?

VALTREX® interferes with the herpes virus's ability to multiply. Inside the body, valaciclovir is rapidly converted into aciclovir, which targets viral DNA synthesis. This process halts the virus’s replication and limits its spread. The medication acts specifically in infected cells, thanks to virus-specific enzymes, reducing the risk to healthy tissue.

This mode of action makes VALTREX® effective against various herpes viruses, including types 1 and 2 of the herpes simplex virus, varicella-zoster virus, cytomegalovirus, and others.

What conditions does VALTREX® treat?

VALTREX® is indicated for adults and adolescents over 12 years of age in treating or preventing:

• Herpes zoster (shingles): Shortens outbreaks and reduces pain.

• Genital herpes: Effective for first episodes and recurring outbreaks.

• Cold sores: Speeds up healing and reduces discomfort.

• Suppressive therapy: Helps prevent future outbreaks in those with frequent recurrences.

• Transmission prevention: Reduces the risk of spreading genital herpes to an uninfected partner when used with safe sexual practices.

• Cytomegalovirus (CMV): Prevents CMV infection and complications after organ transplants.

  
  

How should VALTREX® be used?

VALTREX® tablets are taken by mouth, with or without meals, and should be swallowed with water. Dosage varies by condition:

• Shingles: 1000 mg three times a day for 7 days.

• Genital herpes: 500 mg twice a day for 5–10 days.

• Cold sores: 2 g twice in one day, 12 hours apart.

• Daily prevention: 500 mg once or twice daily.

• CMV after transplant: 2 g four times daily, for up to 90 days.

For patients with kidney impairment, dosing should be adjusted by a healthcare provider.

Who should avoid VALTREX®?

Avoid using VALTREX® if you are allergic to valaciclovir, aciclovir, or any of its ingredients. It is not recommended for:

• Children under 12 years (CMV prevention)

• Individuals under 18 for other indications due to limited data

Use with caution if you have kidney issues, weakened immunity, or are taking other medications that affect the kidneys. During pregnancy or breastfeeding, use only if the benefit outweighs the potential risk.

What are the possible side effects?

Most people tolerate VALTREX® well, but some may experience side effects. Common reactions include:

• Headaches

• Nausea

Less frequent effects may involve:

• Dizziness, confusion, or visual disturbances

• Skin rash, sensitivity to sunlight

• Digestive issues like abdominal discomfort or diarrhea

• Rarely, changes in kidney or liver function

Severe side effects are uncommon and often reversible upon stopping the medication.

How should VALTREX® be stored?

Store the tablets in a cool, dry place at temperatures not exceeding 30°C (86°F).

Keep them out of reach of children and do not use them after the expiry date on the packaging.