The instruction for medical use
of Tsinarix Torgovoye medicine a name
of Tsinarix
the International unlicensed name
Is not present
A dosage form
of the Tablet, coated, on 55 mg
Structure
One tablet contains
active agent - extract of leaves of an artichoke of 55 mg,
excipients: maltodextrin, silicon dioxide, a tsellaktoza 80, kopovidon, krospovidon, talc, magnesium stearate, the titan dioxide, gum arabik, methyl cellulose, calcium carbonate, povidone, glycerin of 85%, silica gel, FD & C blue No. 2 an aluminum pigment of NT (color index No. 73015), D & C yellow No. 10 an aluminum pigment of NT (color index No. 47005:1), eudragit E 12.5, montanglikolevy wax.
The description
Flavovirent round biconvex tablets with a brilliant surface.
Pharmacotherapeutic group
Other drugs for treatment of diseases of biliary tract.
The code of automatic telephone exchange A05AX
Pharmacological action
Pharmacokinetics
absorption Mechanisms for pharmacological active kofeoylkhinny acids, for example, of chlorogenic acid, caffeine acid (its metabolites) and a lyuteolin (flavonoid) are unknown. The maximum of concentration of caffeine acid in blood plasma is observed in 6 - 7 hours after intake of a tsinarix. 33% of chlorogenic acid and 100% of caffeine acid are soaked up after intake.
Chlorogenic acid is hydrolyzed in a stomach, and forms caffeine acid and quinic acid. Metabolites are allocated with urine. Caffeine acid is emitted mainly by means of glomerular filtration.
A pharmacodynamics
the Ingredients forming the basis of efficiency of extract from artichoke leaves are kofeoylkhinny acids (CQAs), flavonoids (for example, lyuteolin) and sesquiterpenic lactones. CQAs increase biliary secretion, thereby having positive impact on dyspepsia. The bile-expelling effect occurs in 30 minutes after artichoke extract intake. Protivogiperlipidemichesky action is provided lyuteoliny which causes considerable suppression of biosynthesis of cholesterol. In experimental works it was shown that CQAs show protective properties concerning liver cells due to prevention of oxidizing damage of cell membranes of a liver.
Indications
- the dispepsichesky disorders and a meteorism connected with disturbance of a zhelchevydeleniye
- chronic diseases of biliary tract
- as a part of complex therapy of a postcholecystectomy syndrome
- as a part of complex therapy of disturbances of lipidic exchange.
The route of administration and doses
Adults and teenagers are more senior than 12 years: 1-2 tablets three times a day before food. Duration of treatment is individual and is defined by the attending physician.
Side effects
are not revealed
Contraindications
- hypersensitivity to the active ingredient or other components which are a part of drug
- heavy dysfunction of a liver
- cholelithiasis
- an empyema of a gall bladder
- children's age
- pregnancy and feeding by a breast.
Special instructions
Influence on driving of the car and control of cars:
Tsinarix does not make any impacts on ability to driving of the car or to control of cars
Medicinal interactions
are not revealed
Overdose
the Form of release and packing
On 12 tablets in blister strip packaging (blister), on 2 blisters together with the instruction for use in a cardboard box is not revealed.
To Store storage conditions at a temperature not over 250C, in external packing for protection against light.
To store out of children's reach!
Period of storage
of 5 years.
Not to apply after the validity juice expiration!
Release from drugstores
Without prescription
the Producer
Montavit Ges. m b. X, Austria
Sabipharm LLP. 050008, Almaty, ave of Abay 66/1. Ph. / fax: (727) 242 00 37.
of Tsinarix Torgovoye medicine a name
of Tsinarix
the International unlicensed name
Is not present
A dosage form
of the Tablet, coated, on 55 mg
Structure
One tablet contains
active agent - extract of leaves of an artichoke of 55 mg,
excipients: maltodextrin, silicon dioxide, a tsellaktoza 80, kopovidon, krospovidon, talc, magnesium stearate, the titan dioxide, gum arabik, methyl cellulose, calcium carbonate, povidone, glycerin of 85%, silica gel, FD & C blue No. 2 an aluminum pigment of NT (color index No. 73015), D & C yellow No. 10 an aluminum pigment of NT (color index No. 47005:1), eudragit E 12.5, montanglikolevy wax.
The description
Flavovirent round biconvex tablets with a brilliant surface.
Pharmacotherapeutic group
Other drugs for treatment of diseases of biliary tract.
The code of automatic telephone exchange A05AX
Pharmacological action
Pharmacokinetics
absorption Mechanisms for pharmacological active kofeoylkhinny acids, for example, of chlorogenic acid, caffeine acid (its metabolites) and a lyuteolin (flavonoid) are unknown. The maximum of concentration of caffeine acid in blood plasma is observed in 6 - 7 hours after intake of a tsinarix. 33% of chlorogenic acid and 100% of caffeine acid are soaked up after intake.
Chlorogenic acid is hydrolyzed in a stomach, and forms caffeine acid and quinic acid. Metabolites are allocated with urine. Caffeine acid is emitted mainly by means of glomerular filtration.
A pharmacodynamics
the Ingredients forming the basis of efficiency of extract from artichoke leaves are kofeoylkhinny acids (CQAs), flavonoids (for example, lyuteolin) and sesquiterpenic lactones. CQAs increase biliary secretion, thereby having positive impact on dyspepsia. The bile-expelling effect occurs in 30 minutes after artichoke extract intake. Protivogiperlipidemichesky action is provided lyuteoliny which causes considerable suppression of biosynthesis of cholesterol. In experimental works it was shown that CQAs show protective properties concerning liver cells due to prevention of oxidizing damage of cell membranes of a liver.
Indications
- the dispepsichesky disorders and a meteorism connected with disturbance of a zhelchevydeleniye
- chronic diseases of biliary tract
- as a part of complex therapy of a postcholecystectomy syndrome
- as a part of complex therapy of disturbances of lipidic exchange.
The route of administration and doses
Adults and teenagers are more senior than 12 years: 1-2 tablets three times a day before food. Duration of treatment is individual and is defined by the attending physician.
Side effects
are not revealed
Contraindications
- hypersensitivity to the active ingredient or other components which are a part of drug
- heavy dysfunction of a liver
- cholelithiasis
- an empyema of a gall bladder
- children's age
- pregnancy and feeding by a breast.
Special instructions
Influence on driving of the car and control of cars:
Tsinarix does not make any impacts on ability to driving of the car or to control of cars
Medicinal interactions
are not revealed
Overdose
the Form of release and packing
On 12 tablets in blister strip packaging (blister), on 2 blisters together with the instruction for use in a cardboard box is not revealed.
To Store storage conditions at a temperature not over 250C, in external packing for protection against light.
To store out of children's reach!
Period of storage
of 5 years.
Not to apply after the validity juice expiration!
Release from drugstores
Without prescription
the Producer
Montavit Ges. m b. X, Austria
Sabipharm LLP. 050008, Almaty, ave of Abay 66/1. Ph. / fax: (727) 242 00 37.