Terfalin 1% 30 ml spray topically
- $17.60
Terfalin of 1% 30 ml
TERFALIN spray ® spray is to synthetic derivatives of allylamine which has the broad antifungal spectrum of action. The activity concerning barmy mushrooms, depending on their look, can be fungicidal or fungistatic. Apply to prevention and treatments of fungal infections of skin
Structure
of 30 g of spray contain
active agent - a terbinafin of a hydrochloride of 300 mg
excipients: alcohol of 96%, tsetomakrogol 1000, propylene glycol, water purified
the Pharmacological
TERFALIN Pharmacodynamics properties ® spray is to synthetic derivatives of allylamine which has the broad antifungal spectrum of action
of TERFALIN ® spray in unusual way changes an early stage of the biosynthesis of sterols happening in mushrooms. It leads to deficiency of ergosterol and to intracellular accumulation of squalene that causes death of a cell of a mushroom. Action of a terbinafin is carried out by inhibition of the enzyme of a skvalenepoksidaza located on a cellular membrane of a mushroom.
TERFALIN ® spray in small concentration has fungicide effect concerning dermatophytes (Trychophyton rubrum, T.mentagrophytes, T.verrucosum, T.violaceum, T.tonsurans, Microsporum canis, Epidermophyton floccosum), mold (in the main C.albicans) and certain dimorphous mushrooms (Pityrosporum orbiculare). The activity concerning barmy mushrooms, depending on their look, can be fungicidal or fungistatic.
Terbinafin does not influence the system of P450 cytochrome at the person and, respectively, metabolism of hormones or other medicines
Indications
Prevention and treatment of fungal infections of skin:
Dermatomycoses of feet (foot fungus) and large folds (tinea cruris), the fungal infections of smooth skin of a body (tinea corporis) caused by such dermatophytes as Trichophyton (including T.rubrum, T.mentagrophytes, T.verrucosum, T.violaceum), Microsporum canis and Epidermophyton floccosum,
multi-colored deprive (Pityriasis versicolor),
the Route of administration caused by Pityrosporum orbiculare (also known as Malassezia furfur) and doses
Drug one is used or twice a day depending on indications. Duration of treatment varies according to indications and weight of an infection. Before use it is necessary to clean and dry affected areas carefully. Drug is sprayed on affected areas in the quantity sufficient for their careful moistening, and, besides, applied on adjacent sites as struck, and intact skin.
The recommended treatment duration:
Dermatomycosis of smooth skin and large folds: 1 week, 1 times/days
Dermatomycosis of feet: 1 week, 2 times/days
Multi-colored deprive: 1 week, 2 times/days.
Clinical improvement occurs within several days. In case of irregular treatment or premature its termination is available risk of a recurrence of an infection. In case in a week signs of improvement are not noted, it is necessary to verify the diagnosis.
For elderly people of change of the mode of dosing it is not required
Side effects
Often: in sites of application of drug there can be a reddening,
the feeling of an itching or burning
is rare: allergic reactions
of the Contraindication
- hypersensitivity to any of drug components
- the lactation period,
- children's age (up to 2 years),
- chronic or active diseases of a liver, HPN (KK less than 50 ml/min.).
Medicinal interactions
there are no data on medicinal interaction concerning topical administration of a terbinafin
the Special
instructions TERFALIN®, spray for topical administration of 1%, is intended only for external use, and not intended for intake, intranasal use, use in ophthalmologic practice and intravaginalny use.
It is necessary to avoid hit of drug on a mucous membrane of eyes. At hit of drug in eyes, they should be washed immediately with flowing water and if necessary to consult with the doctor.
In cases of irritation, allergic reactions or deteriorations in health it is necessary to stop use of drug and it is necessary to appoint the corresponding treatment.
With care apply drug on the damaged sites of skin as alcohol can cause irritation.
There are no bases to assume that for elderly people it is required to change drug dosing or that they note the side effects differing from those at patients of younger age. In case of use in this age group of drug it is necessary to consider a possibility of the accompanying abnormal liver function or kidneys.
The infected sites should not be fitted by close clothes.
Patients with an infection of legs have to wear well adjusted and ventilated shoes. It is necessary to change footwear and socks, at least, once a day.
Observance of the recommended treatment duration is important for achievement of the best clinical effect.
It is necessary to wash hands after each use for prevention of planting from the infected sites.
Pregnancy and a lactation
of Adequate and well controlled tests on pregnant women it was not carried out. During pregnancy it is applied with care and only in the presence of strict indications. For the period of treatment it is necessary to stop breastfeeding.
Features of influence of medicine on ability to run the vehicle or potentially dangerous mechanisms
the Overdose
Is possible only at accidental intake.
Symptoms: a headache, dizziness, nausea, vomiting, pains in epigastriums, rash, frequent urination. It is also necessary to consider the content in alcohol drug (28.7% of alcohol).
Treatment: use of activated carbon and symptomatic and maintenance therapy
TERFALIN spray ® spray is to synthetic derivatives of allylamine which has the broad antifungal spectrum of action. The activity concerning barmy mushrooms, depending on their look, can be fungicidal or fungistatic. Apply to prevention and treatments of fungal infections of skin
Structure
of 30 g of spray contain
active agent - a terbinafin of a hydrochloride of 300 mg
excipients: alcohol of 96%, tsetomakrogol 1000, propylene glycol, water purified
the Pharmacological
TERFALIN Pharmacodynamics properties ® spray is to synthetic derivatives of allylamine which has the broad antifungal spectrum of action
of TERFALIN ® spray in unusual way changes an early stage of the biosynthesis of sterols happening in mushrooms. It leads to deficiency of ergosterol and to intracellular accumulation of squalene that causes death of a cell of a mushroom. Action of a terbinafin is carried out by inhibition of the enzyme of a skvalenepoksidaza located on a cellular membrane of a mushroom.
TERFALIN ® spray in small concentration has fungicide effect concerning dermatophytes (Trychophyton rubrum, T.mentagrophytes, T.verrucosum, T.violaceum, T.tonsurans, Microsporum canis, Epidermophyton floccosum), mold (in the main C.albicans) and certain dimorphous mushrooms (Pityrosporum orbiculare). The activity concerning barmy mushrooms, depending on their look, can be fungicidal or fungistatic.
Terbinafin does not influence the system of P450 cytochrome at the person and, respectively, metabolism of hormones or other medicines
Indications
Prevention and treatment of fungal infections of skin:
Dermatomycoses of feet (foot fungus) and large folds (tinea cruris), the fungal infections of smooth skin of a body (tinea corporis) caused by such dermatophytes as Trichophyton (including T.rubrum, T.mentagrophytes, T.verrucosum, T.violaceum), Microsporum canis and Epidermophyton floccosum,
multi-colored deprive (Pityriasis versicolor),
the Route of administration caused by Pityrosporum orbiculare (also known as Malassezia furfur) and doses
Drug one is used or twice a day depending on indications. Duration of treatment varies according to indications and weight of an infection. Before use it is necessary to clean and dry affected areas carefully. Drug is sprayed on affected areas in the quantity sufficient for their careful moistening, and, besides, applied on adjacent sites as struck, and intact skin.
The recommended treatment duration:
Dermatomycosis of smooth skin and large folds: 1 week, 1 times/days
Dermatomycosis of feet: 1 week, 2 times/days
Multi-colored deprive: 1 week, 2 times/days.
Clinical improvement occurs within several days. In case of irregular treatment or premature its termination is available risk of a recurrence of an infection. In case in a week signs of improvement are not noted, it is necessary to verify the diagnosis.
For elderly people of change of the mode of dosing it is not required
Side effects
Often: in sites of application of drug there can be a reddening,
the feeling of an itching or burning
is rare: allergic reactions
of the Contraindication
- hypersensitivity to any of drug components
- the lactation period,
- children's age (up to 2 years),
- chronic or active diseases of a liver, HPN (KK less than 50 ml/min.).
Medicinal interactions
there are no data on medicinal interaction concerning topical administration of a terbinafin
the Special
instructions TERFALIN®, spray for topical administration of 1%, is intended only for external use, and not intended for intake, intranasal use, use in ophthalmologic practice and intravaginalny use.
It is necessary to avoid hit of drug on a mucous membrane of eyes. At hit of drug in eyes, they should be washed immediately with flowing water and if necessary to consult with the doctor.
In cases of irritation, allergic reactions or deteriorations in health it is necessary to stop use of drug and it is necessary to appoint the corresponding treatment.
With care apply drug on the damaged sites of skin as alcohol can cause irritation.
There are no bases to assume that for elderly people it is required to change drug dosing or that they note the side effects differing from those at patients of younger age. In case of use in this age group of drug it is necessary to consider a possibility of the accompanying abnormal liver function or kidneys.
The infected sites should not be fitted by close clothes.
Patients with an infection of legs have to wear well adjusted and ventilated shoes. It is necessary to change footwear and socks, at least, once a day.
Observance of the recommended treatment duration is important for achievement of the best clinical effect.
It is necessary to wash hands after each use for prevention of planting from the infected sites.
Pregnancy and a lactation
of Adequate and well controlled tests on pregnant women it was not carried out. During pregnancy it is applied with care and only in the presence of strict indications. For the period of treatment it is necessary to stop breastfeeding.
Features of influence of medicine on ability to run the vehicle or potentially dangerous mechanisms
the Overdose
Is possible only at accidental intake.
Symptoms: a headache, dizziness, nausea, vomiting, pains in epigastriums, rash, frequent urination. It is also necessary to consider the content in alcohol drug (28.7% of alcohol).
Treatment: use of activated carbon and symptomatic and maintenance therapy
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