Tardyferon® (Ferrous Sulfate) 30 Tabs

Compound

One tablet contains Ferrous sulfate sesquihydrate 256.30 mg, the quantitative iron equivalent of 80 mg

Excipients

For tablet core Ascorbic acid, anhydrous mucoproteose, potato starch, methyl methacrylate copolymer of methacrylic acid (Eudrogit S), triethyl citrate, povidone, talc, magnesium stearate, hydrogenated castor oil, magnesium trisilicate

For tablet shell

Basic butylated methacrylic copolymer (Eudragit E), talc, titanium dioxide, sodium bicarbonate, carnauba wax, sucrose.

Pharmacological properties

Combined antianemic drug.

Ferrous sulfate, which is part of the preparation, compensates for the deficiency of iron in the body. Iron is a part of hemoglobin, myoglobin, cytochrome C, participates in reversible oxygen uptake, being a structural component of heme, and takes part in erythropoiesis.

Ascorbic acid is an antioxidant that increases the absorption of iron by 4 times.

Mucoproteosis is a macromolecular fraction of the mucous membrane of the gastrointestinal tract of sheep, containing aminoglycosides and organically bound sulfates.

Mucoproteosis delays the release of iron ions from the pellets for 7 hours, which causes their absorption from the upper parts of the small intestine and the absence of a local irritating effect on the gastric mucosa.

Pharmacokinetics

Suction

Iron is absorbed mainly from the duodenum and small intestine. Iron bioavailability is 5-35%.

The mucoproteose-iron complex fills the crypts of the intestinal mucosa, which ensures the contact of the complex with the larger surface of the mucous membrane, thereby enhancing the absorption of iron.

Distribution and metabolism

Iron is almost completely bound to plasma transferrins and is involved in the formation of hemoglobin, myoglobin, cytochrome oxidase, or is deposited in body tissues in the form of ferritin.

Withdrawal

Iron is excreted in feces, urine and sweat.

Interaction with other medicinal products

To avoid interactions between different medicines, especially with iron salts, tell your doctor or pharmacist about any other medicines you are taking.

Indications for use

Iron deficiency (hypochromic) anemia, especially caused by iron deficiency due to insufficient intake of it with food, due to physiologically determined increased demand and chronic blood loss. Latent iron deficiency, especially in women of childbearing age, in adolescents during periods of increased growth and in the elderly.

As a preventive measure in case of increased iron requirements to prevent iron deficiency anemia during pregnancy, in the postpartum period and during breastfeeding.

Contraindications

• anemia not associated with iron deficiency (hemolytic anemia, megaloblastic anemia caused by vitamin B12


• deficiency, aplastic anemia).


• hemosiderosis:


• hemochromatosis.

Pregnancy and lactation

The drug is prescribed during pregnancy and lactation as indicated.

Special instructions

Reduced iron content in the blood, developed as a result of inflammatory reactions. does not respond to therapy with the drug "Tardyferon 80 mg film-coated tablets" Due to the presence of sucrose in the composition of the drug. it should not be used in case of fructose intolerance, glucose / galactose malabsorption syndrome, or sucrase-isomaltase deficiency (rare metabolic disorders).

Risk of an allergic reaction due to the presence of castor oil, especially in children under 3 years of age.

Side effect

• Like all oral iron preparations, Tardyferon can cause darkening of the stool, which is not clinically relevant.


• In rare cases, nausea, constipation, and diarrhea may occur.

Method of administration and dosage

It is used only in adults and children over 6 years old.

Children over six years of age 1 tablet daily.

Children over 10 years old and adults 1-2 tablets a day.

With regard to prophylactic treatment in pregnant women, usually 1 tablet is used every day or every other day during the last 2 trimesters of pregnancy (or starting from the 4th month).

Overdose

Symptoms: irritation and necrosis of the gastrointestinal tract, accompanied by nausea, vomiting, shock.

Treatment: ingest raw eggs and milk, which will ensure the absorption of iron and its subsequent excretion. If the drug has recently been taken, you can remove it by inducing vomiting.

Also, for this purpose, the stomach is washed with a 1% aqueous solution of sodium bicarbonate. Iron antidote - deferoxamine in the manufacturer's recommended dose.

Storage conditions

Store at room temperature, out of the reach of children.
Shelf life - 5 years