The instruction for medical use of POSIFORMIN medicine the Trade name Posiformin Mezhdunarodnoye the unlicensed name Bibrokatol Lekarstvennaya a form oculentum, 2% Structure of 1 g of ointment contains active agent – bibrokatol 20 mg, excipients: paraffin white soft, liquid paraffin, lanolin. The description Uniform ointment (in the form of suspension) from yellow till gray-yellow color Pharmacotherapeutic group the Drugs used in ophthalmology. Other antimicrobial drugs. Bibrokatol. The ATX S01A X05 code the Pharmacological Bibrokatol Pharmacokinetics properties is almost not dissolved in water and therefore it practically does not get in an eye and does not get to watery moisture. Thanks to it use of a bibrokatol in ophthalmology is limited to topical treatment of nonspecific irritations and inflammations and also treatment of wounds of external covers of an eye. After topical ophthalmologic administration of noticeable system absorption of a bibrokatol does not occur. A pharmacodynamics Bibrokatol is the compound of bismuth having the antiseptic and knitting properties and also ability to inhibit secretion of mucous membranes and wounds. The mechanism of its action is caused by structure of a bibrokatol who represents phenolic derivative a tetrabrompirokatekhin and bismuth of hydroxide. On mucous membranes and wounds bibrokatol causes sedimentation of proteins and tightening of blankets of fabrics. It leads to formation of a protective layer which prevents penetration of pathogenic microorganisms. Such knitting effect causes nonspecific inhibition of inflammation and secretion. Indications - nonspecific irritations of external covers of an eye of non-infectious genesis, chronic inflammation of an edge of the lids (chronic blepharitis), fresh not contaminated wounds of a cornea the Route of administration and doses put the Strip of ointment 0.5 cm long in a conjunctive bag or apply on the affected eyelid of 3-5 times a day. Dosing for adults and children age is more senior than 6 years identical. Drug should be used before disappearance of symptoms. Usually duration of treatment does not exceed 14 days. Side effects - the reactions of hypersensitivity (allergy) and irritation of eyes which are followed by such symptoms as an itching, hyperaemia or an eye swelled, eye pain, a face edema, rushes of blood to the person Protivopokazaniya - hypersensitivity to active ingredient or to any excipients of drug Medicinal interactions of Special researches of medicinal interactions of drug it was not carried out. At simultaneous use of drug with other eye drops or ointments it is necessary to maintain, at least, a 15-minute interval between drawings. Posiformin should be put in the last turn. The special instructions Excipient lanolin can cause local skin reactions (for example, contact dermatitis). During drug treatment it is impossible to use contact lenses. When putting oculentum it is necessary to avoid any contact of a tip of a tuba with an eye or skin. Pregnancy and a lactation As clinical data on use of drugs of a bibrokatol during pregnancy or feeding by a breast are absent, during these periods it is possible to appoint oculentum of Posiformin only after careful assessment of a ratio of advantage and risk of such use. Features of influence on ability to run the vehicle or potentially dangerous mechanisms Thanks to the fat consistence right after use drug can quickly affect visual acuity and, thus, on speed of response during control of motor transport or works with mechanisms. The overdose After topical administration of drug of development of system side reactions is not expected because of very low extent of penetration of a bibrokatol through biological membranes in an internal chamber of the eye. A form of release and packing On 5 g of oculentum in the aluminum tuba with internal protective varnish coating equipped with a tip and a cap (polyethylene). On 1 tuba together with the instruction for medical use in the state and Russian languages place Storage conditions in a cardboard box to Store at a temperature not above 25 °C. To store out of children's reach! 3 years not to apply a period of storage after an expiration date. A period of storage after the first opening of packing - 4 weeks. Prescription status Without prescription of URSAPHARM Arzneimittel GmbH Industriyestrasse 35, 66129 Saarbruecken, Germany (Industriestrasse 35, 66129 Saarbrucken, Germany) the Owner of the registration certificate of URSAFARM Artsnaymittel GmbH, Saarbruecken, Germany (URSAPHARM Arzneimittel GmbH, Saarbrucken, Germany) the Address of the organization in the territory of the Republic of Kazakhstan the accepting claim (offer) from consumers on quality of medicine and responsible for post-registration observation for safety of medicine: Representative office of LLC Sona-Pharm in Almaty, RK Almaty, Gogol St. 77/85, office 68
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