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PK-Merz (Amantadine) 100 mg, 30 tablets

  • $30.00
Sku: 789db279a3f6
Ingredient: Amantadine

What is PK-Merz (Amantadine)?

PK-Merz is a medication that contains the active substance amantadine sulfate.

It is commonly used to manage symptoms of Parkinson's disease and certain movement disorders caused by antipsychotic medications.

PK-Merz works by stimulating dopamine release, which helps to alleviate muscle stiffness, tremors, and slowed movements.

Each tablet contains 100 mg of amantadine and is covered with a protective film.

The medication plays a critical role in treating neurological conditions, specifically those affecting motor control.


What are the indications for using PK-Merz?

PK-Merz is prescribed to treat:

  • Parkinson's disease symptoms, such as muscle rigidity, tremors, and difficulty moving (hypokinesia or akinesia).
  • Extrapyramidal disorders, which are movement issues caused by certain medications, particularly neuroleptics (antipsychotics).


Who should avoid using PK-Merz?

PK-Merz is contraindicated in the following cases:

  • People with hypersensitivity to any of the ingredients.
  • Patients with severe heart conditions like heart failure, cardiomyopathy, or heart rhythm disorders.
  • Those with electrolyte imbalances (e.g., low potassium or magnesium levels).
  • Patients with severe kidney failure.
  • Pregnant or breastfeeding women.
  • Children under 18 years of age.
  • Individuals with specific hereditary conditions affecting sugar metabolism, such as galactose intolerance or lactase deficiency.


What precautions should be taken when using PK-Merz?

Before starting treatment with PK-Merz, your doctor will monitor your heart function using an electrocardiogram (ECG) and continue these checks during the first few weeks of therapy. Patients at risk for electrolyte imbalances, like those on diuretics or experiencing frequent vomiting, will need regular blood tests to check potassium and magnesium levels.

If you experience symptoms like heart palpitations, dizziness, or fainting, stop taking PK-Merz immediately and contact your doctor, as these could indicate a heart rhythm issue.

Patients with implanted pacemakers, kidney problems, or neurological conditions should be assessed by their doctor to determine if PK-Merz is appropriate. Prolonged use may also lead to peripheral edema, particularly in those with chronic heart failure.


Can PK-Merz interact with other medications?

Yes, PK-Merz has several drug interactions, especially with medications that affect the heart's electrical activity by prolonging the QT interval. Combining PK-Merz with these drugs can increase the risk of dangerous heart arrhythmias. Some examples include:

  • Certain antiarrhythmic drugs (e.g., amiodarone).
  • Antipsychotics (e.g., thioridazine).
  • Some antidepressants (e.g., amitriptyline).
  • Certain antibiotics (e.g., erythromycin).
  • Antifungal medications like azoles.


If you take any of these medications, discuss this with your healthcare provider before starting PK-Merz.


How should PK-Merz be taken?

  • Initial dosage: Start with one tablet per day for the first three days.
  • Maintenance dosage: Gradually increase to two tablets per day, with the possibility of increasing by one tablet each week.
  • Maximum daily dose: The highest recommended dose is 600 mg per day, divided into doses throughout the day. The last dose should be taken no later than 4:00 p.m. to avoid sleep disturbances.


PK-Merz is taken orally, after meals, with a small amount of water.


What are the common side effects of PK-Merz?

Some common side effects of PK-Merz include:

  • Anxiety, irritability, and visual hallucinations.
  • Dizziness, headaches, and difficulty sleeping.
  • Nausea, vomiting, dry mouth, and loss of appetite.
  • Difficulty with urination, particularly in men with an enlarged prostate.
  • Skin conditions like a marbled appearance, especially on the ankles and legs.


More severe side effects, such as heart rhythm problems, blurred vision, or seizures, are rare but require immediate medical attention.


How should PK-Merz be stored?

PK-Merz should be stored at a temperature no higher than 25°C (77°F), in a place out of reach of children.

Make sure to check the expiration date and avoid using the medication past this date.

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