Pikolaks 7.5 mg (10 tablets)

The instruction for medical use


of PIKOLAKS medicine

the Trade name
of Pikolaks

the International unlicensed name
of Sodium pikosulfat

the Dosage form
of the Tablet, 7.5 mg

Structure
One tablet contains
active agent: pikosulfat sodium in terms of 100% anhydrous substance - 7.5 mg
excipients: lactoses monohydrate, starch corn, starch prezhelatinizirovanny 1500, silicon dioxide colloidal anhydrous, magnesium stearate.

The description
of the Tablet of a ploskotsilindrichesky form, white or almost white color, with risky and a facet

Pharmacotherapeutic group
Contact depletive. Sodium pikosulfat.
ATH A06AB08 code

the Pharmacological

Pharmacokinetics Later properties of intake reaches a large intestine without significant absorption where under the influence of bacterial flora it is split with formation of an active form (free biphenol). The laxative effect is observed in 6-12 hours after reception, the expressiveness of laxative effect does not correlate with the level of active biphenol in blood plasma.
The pharmacodynamics
Contact depletive of triarilmetanovy group, is activated in a large intestine under the influence of bacterial sulphatases, substance which is released at the same time stimulates sensitive nerve terminations of a mucous membrane of intestines, enhances his motility. Pikolaks works softly, use of drug is not followed by tenesmus and enterospasms.
At course treatment of Pikolaks stimulates growth and metabolic activity of normal intestinal microflora.

Indications
- the constipations or cases demanding defecation simplification

the Route of administration and doses
Appoint inside. At reception for the night the laxative effect occurs in the morning.
To adults and children 10 years – on 5-10 mg (on average 7.5 mg) are more senior than 1 times a day. At heavy and obstipations the adult about 15 mg disposable are recommended to accept.
For children there is effective a single dose of drug. If necessary the course of treatment at the child can be prolonged, but it is preferable to limit it three days. Duration of treatment is established individually and usually should not exceed 7 days.

Side effects
At short-term administration of drug side effects are observed seldom.
At prolonged use of drug in much the overestimated doses disturbances are possible:
– allergic reactions (Quincke's disease, skin rash, a small tortoiseshell, an itching)
– loss of potassium, sodium and other electrolytes, perhaps development of dehydration
It is rare
– the dispeptic phenomena, vomiting, nausea, spasms and an abdominal pain, diarrhea, a meteorism, pain in a stomach and area of an anus, strengthening of motility of intestines which pass at reduction of a dose of drug
Very seldom
– a headache, increased fatigue, drowsiness,

Contraindication spasms
- hypersensitivity to drug components
- intestinal impassability
- acute inflammatory bowel diseases and acute diseases of abdominal organs (including an acute appendicitis, nonspecific ulcer colitis, peritonitis)
- abdominal pain, nausea and vomiting of not clear origin
- a state after digestive tract surgery
- heavy dehydration
- pregnancy and the period of a lactation
- children's age up to 10 years


the Electrolytic imbalance can lead Medicinal interactions to decrease in tolerance to cardiac glycosides. Diuretics or glucocorticosteroids can enhance expressiveness of the hypopotassemia caused by Pikolaks's use in high doses. Simultaneous treatment by antibiotics can reduce laxative effect of drug.


It is not necessary to accept special instructions As well as other depletive, Pikolaks daily or a long time. If there is a need for daily intake of depletive, it is necessary to find out the cause of constipations. Prolonged use of depletive can lead to an electrolytic imbalance and a hypopotassemia and also to become the reason of accustoming and constipations owing to effect of ricochet.
To use with care to elderly people, at a hypopotassemia, the increased magnesium content in blood, to patients with the weakened organism.
Drug contains lactose that should be meant to persons with a hereditary lactose intolerance.
The feature of influence of drug on ability to run transport and potentially dangerous mechanisms
does not influence.

Overdose
Symptoms: frequent liquid excrements, spasms (gripes) in a stomach and clinically significant disturbances of water and electrolytic balance (a hypopotassemia, loss of other electrolytes and liquid), ischemia of a mucous membrane of a large intestine. The long overdose leads ment of chronic diarrhea and an abdominal pain, hypopotassemia, secondary hyper aldosteronism, damage of kidneys and development of a nephrolithiasis, a metabolic alkalosis and muscle weakness as result of a hypopotassemia is possible.
Treatment: drug withdrawal, gastric lavage, reception of enterosorbents (activated carbon), symptomatic treatment (carrying out correction of water and electrolytic balance, use of spasmolysants).

The form of release and packing
On 10 tablets place in blister strip packaging from a film of the polyvinylchloride colourless and printing aluminum foil varnished.
On 1 or 3 blister strip packagings together with the instruction for medical use in the state and Russian languages place in a pack from cardboard.


To Store storage conditions in the place protected from light at a temperature not higher than 25 os.
To store out of children's reach!

A period of storage
2 years
not to use drug after the termination of the expiration date specified on packing.

Prescription status
Without prescription


PJSC Pharmak Producer, Ukraine, 04080, Kiev, st. of Frunze, 63.

The owner of the registration certificate
of PJSC Pharmak, Ukraine

the Address of the organization accepting in the territory of the Republic of Kazakhstan claims from consumers on quality of products (goods) the Republic of Kazakhstan, 050009 Almaty, st. of Abay 157, office 5tel/fax: +7 (727) 250 66 23, the e-mail address: Djatlova88@mail.ru