Trade name
Pantestin-Darnitsa
the International unlicensed name
Is not present
the Dosage form
Gel of 15 g
Structure
1 g of gel contains
active agents: dekspantenol (D-panthenol) of 50 mg, miramistin in terms of anhydrous substance of 5 mg
excipients: propylene glycol, polyethyleneglycol (a macrogoal 400), half-oxameasures (proksanol 268), cetyl alcohol, stearyl alcohol, the water purified.
The description
Gel of white color with a slight specific smell
Pharmacological group
Other drugs for hyper scarring treatment
the ATX D03AX Code
the Pharmacological
Dekspantenol Pharmacokinetics properties from gel Pantestin-Darnitsa practically does not come to a system blood stream. It is metabolized deksapantenol in fabrics on the site of application. Miramistin, thanks to properties of polymeric substances of an ointment basis keeps on a wound surface and is not soaked up in a system blood stream.
The pharmacodynamics
Active agent of drug Pantestin-Darnitsa deksapantenol is provitamin. When drawing on skin deksapantenol gets into cells of an epithelium and it is transformed to pantothenic acid which is a component of a coenzyme And, the synthesis of plastic material which is taking part in processes. It leads to strengthening of processes of forming and regeneration of skin, in the hardly healing, complicated wounds.
As the hardly healing wounds, as a rule, are complicated by a wound fever for the purpose of prevention and treatment of a wound fever the cationic antiseptic agent – miramistin which antimicrobic action supplements effect of a deksapantenol is entered into drug.
Indications
- for treatment of wounds of various localization and genesis, including postoperative wounds, trophic ulcers and decubituses in a regeneration phase (2nd phase of wound process) in surgery
- for treatment of sunblisters, for treatment of the granulating burn wounds, preparation them to an autodermoplastika and after plastic surgeries for improvement of engraftment of skin transplants in Combustiology
- for prevention of radiation injuries of mucous membranes, skin and surrounding fabrics and also for treatment of beam ulcers in a regeneration phase in radiation medicine
- for treatment of infections of skin, in particular, again infected eczemas and neurodermatitises
- for treatment of small grazes, cuts, scratches, burns, an intertrigo and prevention of their infection at household traumatism
- at treatment of erosion of a neck of the uterus, erosive colpitises and injuries of a mucous membrane of a vagina to gynecology
- for treatment of diseases of the parodont (catarrhal, ulcer and necrotic ulitis, the localized periodontal disease, a generalized periodontal disease), treatment of diseases of a mucous membrane of an oral cavity (stomatitis, chronic recurrent aphthous stomatitis), traumatic damages of a mucous membrane of an oral cavity (prosthetic stomatitis) in stomatology.
The route of administration and doses
Pantestin-Darnitsa apply Gel locally. After standard processing of a wound surface, gel is applied with a thin layer on a wound, then apply a sterile gauze bandage if gel is required applied on a dressing material, and then on a wound. In the presence of exudate before drug use the wound needs to be washed with solution of Furacilin (1:5000) or peroxide of hydrogen (3%) and to dry up a gauze napkin. In dermatological diseases and sunblisters the treatment can be performed by a bespovyazochny method, 2-3 times a day apply gel on the struck surface. In gynecologic diseases (erosion of a neck of the uterus, erosive colpitises, etc.) previously impregnate with gel a gauze tampon which is entered deeply into a vagina in a prone position.
In dental diseases drug is used only to adult patients. Drug for topical administration in an oral cavity. After the individual
of alny hygiene to rinse an oral cavity, to apply gel with a thin layer on the surface of gums or the site of damage of a mucous membrane of an oral cavity. Within an hour not to drink and not to eat food. At treatment of traumatic damages of a mucous membrane of an oral cavity (prosthetic stomatitis) after putting gel on area of defeat it is possible to use dentures. 2-3 times a day apply gel. Duration of treatment is 7-10 days, before full healing of defeat or reduction of inflammatory processes.
Side effects
- allergic reactions (erubescence and an itching)
- feeling of easy burning which passes independently and does not demand from -
drug exchanges.
Contraindications
- hypersensitivity to drug components
- the first phase of wound process at the expressed purulent exudation
- for appliques on a perforated tympanic membrane in connection with a cash -
chiy in it a miramistina.
Medicinal interactions
Drug cannot be used together with soap (anionaktivny substances) and other antiseptic agents which inactivate antimicrobic action of a miramistin.
Some decrease in resistance of microorganisms to antibiotics at simultaneous use is noted with miramistiny.
Dekspantenol can strengthen action of the depolarizing muscle relaxants and weaken action of not depolarizing muscle relaxants thanks to ability to stimulate synthesis of acetylcholine.
During treatment it is not necessary to apply along with other drugs without preliminary consultation with the doctor.
Special instructions
It is necessary to avoid hit of gel in eyes.
It is not necessary to apply with other drugs without preliminary consultation of the doctor.
Children
Are not present data on use of drug in children's practice.
Pregnancy, the lactation period
At pregnancy it is necessary to avoid use of drug on big parts of the body. During feeding by a breast use is allowed only on small parts of the body.
Features of influence of drug on ability to run motor transport and potentially dangerous mechanisms
the Overdose
At topical administration does not influence the overdose is improbable since active components of drug do not come to a system blood stream.
A form of release and packing
On 15 g in aluminum tubas with a membrane for the medical purposes or import, screwing up plastic covers. Each tuba together with the instruction for medical use in the state and Russian languages is placed in a pack from cardboard.
To Store storage conditions in original packing, at a temperature not above 25 °C.
Freezing of drug is not allowed.
To store out of children's reach!
A period of storage
2 years
not to use after an expiration date
Prescription status
Without prescription
CIAO Producer Pharmaceutical Darnitsa
Pantestin-Darnitsa
the International unlicensed name
Is not present
the Dosage form
Gel of 15 g
Structure
1 g of gel contains
active agents: dekspantenol (D-panthenol) of 50 mg, miramistin in terms of anhydrous substance of 5 mg
excipients: propylene glycol, polyethyleneglycol (a macrogoal 400), half-oxameasures (proksanol 268), cetyl alcohol, stearyl alcohol, the water purified.
The description
Gel of white color with a slight specific smell
Pharmacological group
Other drugs for hyper scarring treatment
the ATX D03AX Code
the Pharmacological
Dekspantenol Pharmacokinetics properties from gel Pantestin-Darnitsa practically does not come to a system blood stream. It is metabolized deksapantenol in fabrics on the site of application. Miramistin, thanks to properties of polymeric substances of an ointment basis keeps on a wound surface and is not soaked up in a system blood stream.
The pharmacodynamics
Active agent of drug Pantestin-Darnitsa deksapantenol is provitamin. When drawing on skin deksapantenol gets into cells of an epithelium and it is transformed to pantothenic acid which is a component of a coenzyme And, the synthesis of plastic material which is taking part in processes. It leads to strengthening of processes of forming and regeneration of skin, in the hardly healing, complicated wounds.
As the hardly healing wounds, as a rule, are complicated by a wound fever for the purpose of prevention and treatment of a wound fever the cationic antiseptic agent – miramistin which antimicrobic action supplements effect of a deksapantenol is entered into drug.
Indications
- for treatment of wounds of various localization and genesis, including postoperative wounds, trophic ulcers and decubituses in a regeneration phase (2nd phase of wound process) in surgery
- for treatment of sunblisters, for treatment of the granulating burn wounds, preparation them to an autodermoplastika and after plastic surgeries for improvement of engraftment of skin transplants in Combustiology
- for prevention of radiation injuries of mucous membranes, skin and surrounding fabrics and also for treatment of beam ulcers in a regeneration phase in radiation medicine
- for treatment of infections of skin, in particular, again infected eczemas and neurodermatitises
- for treatment of small grazes, cuts, scratches, burns, an intertrigo and prevention of their infection at household traumatism
- at treatment of erosion of a neck of the uterus, erosive colpitises and injuries of a mucous membrane of a vagina to gynecology
- for treatment of diseases of the parodont (catarrhal, ulcer and necrotic ulitis, the localized periodontal disease, a generalized periodontal disease), treatment of diseases of a mucous membrane of an oral cavity (stomatitis, chronic recurrent aphthous stomatitis), traumatic damages of a mucous membrane of an oral cavity (prosthetic stomatitis) in stomatology.
The route of administration and doses
Pantestin-Darnitsa apply Gel locally. After standard processing of a wound surface, gel is applied with a thin layer on a wound, then apply a sterile gauze bandage if gel is required applied on a dressing material, and then on a wound. In the presence of exudate before drug use the wound needs to be washed with solution of Furacilin (1:5000) or peroxide of hydrogen (3%) and to dry up a gauze napkin. In dermatological diseases and sunblisters the treatment can be performed by a bespovyazochny method, 2-3 times a day apply gel on the struck surface. In gynecologic diseases (erosion of a neck of the uterus, erosive colpitises, etc.) previously impregnate with gel a gauze tampon which is entered deeply into a vagina in a prone position.
In dental diseases drug is used only to adult patients. Drug for topical administration in an oral cavity. After the individual
of alny hygiene to rinse an oral cavity, to apply gel with a thin layer on the surface of gums or the site of damage of a mucous membrane of an oral cavity. Within an hour not to drink and not to eat food. At treatment of traumatic damages of a mucous membrane of an oral cavity (prosthetic stomatitis) after putting gel on area of defeat it is possible to use dentures. 2-3 times a day apply gel. Duration of treatment is 7-10 days, before full healing of defeat or reduction of inflammatory processes.
Side effects
- allergic reactions (erubescence and an itching)
- feeling of easy burning which passes independently and does not demand from -
drug exchanges.
Contraindications
- hypersensitivity to drug components
- the first phase of wound process at the expressed purulent exudation
- for appliques on a perforated tympanic membrane in connection with a cash -
chiy in it a miramistina.
Medicinal interactions
Drug cannot be used together with soap (anionaktivny substances) and other antiseptic agents which inactivate antimicrobic action of a miramistin.
Some decrease in resistance of microorganisms to antibiotics at simultaneous use is noted with miramistiny.
Dekspantenol can strengthen action of the depolarizing muscle relaxants and weaken action of not depolarizing muscle relaxants thanks to ability to stimulate synthesis of acetylcholine.
During treatment it is not necessary to apply along with other drugs without preliminary consultation with the doctor.
Special instructions
It is necessary to avoid hit of gel in eyes.
It is not necessary to apply with other drugs without preliminary consultation of the doctor.
Children
Are not present data on use of drug in children's practice.
Pregnancy, the lactation period
At pregnancy it is necessary to avoid use of drug on big parts of the body. During feeding by a breast use is allowed only on small parts of the body.
Features of influence of drug on ability to run motor transport and potentially dangerous mechanisms
the Overdose
At topical administration does not influence the overdose is improbable since active components of drug do not come to a system blood stream.
A form of release and packing
On 15 g in aluminum tubas with a membrane for the medical purposes or import, screwing up plastic covers. Each tuba together with the instruction for medical use in the state and Russian languages is placed in a pack from cardboard.
To Store storage conditions in original packing, at a temperature not above 25 °C.
Freezing of drug is not allowed.
To store out of children's reach!
A period of storage
2 years
not to use after an expiration date
Prescription status
Without prescription
CIAO Producer Pharmaceutical Darnitsa
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