Ornisid 250 mg (20 tablets)
- $18.10
ORNISID
the Trade name Ornisid
Mezhdunarodnoye unlicensed nazvaniyeornidazol (Ornidazol)
Medicinal formatabletka of 250 mg coated
SostavOdna a tablet soderzhitaktivny substance - ornidazol 250.00 mg, excipients: - microcrystalline cellulose, starch, methylhydroxyethyl cellulose, magnesium stearate. A cover - hydroksipropilmetit cellulose, talc, the titan OpisanieKruglye dioxide, biconvex, white or almost white tablets, coated, with risky on the one hand. Pharmacological svoystvaornisid (ornidazol) possesses antibacterial and antiprotozoan action. Interacting with DNA of a microbic cell, causes disturbance of its helical structure, a rupture of threads, suppresses synthesis of nucleic acids and causes death of microbic cells and cells of protozoa. Ornisid (ornidazol) is active concerning protozoa: Trichomonas vaginalis, Entamoeba histolitica, Gardnerella vaginalis. Giardia intestinalis, Lambilia. And also concerning anaerobic cocci: Peptostrepococcus, Peptococcus. Ornidazol is easily absorbed from digestive tract. Bioavailability – 90%. The maximum concentration in plasma is reached within 2 hours. After oral use of the maximum daily dose of 1.5 g the concentration of an ornidazol in blood plasma reaches 30mg/ml, on the expiration of 24 hours the plasma concentration goes down to 9mg/ml. Linking with blood proteins makes menee15%. Ornidazol well gets into all fabrics and liquids of an organism, including cerebrospinal liquid. Biotransformation of an ornidazol occurs in a liver. Elimination half-life of an ornidazol makes 12-14 hours. After single dose of 85% of a dose it is brought out of an organism within 5 days in the form of metabolites. Ornidazol is brought generally in the form of metabolites by kidneys (63%) and with excrement (22%). Elimination of an ornidazol is possible also in the bilious way.
Indications
trichomoniasis at women and men: mecotic vulvovaginitis, urethritis, bartholinitis, cervicitis, prostatitis, adnexitis, etc.
amebiasis: the amoebic dysentery, an abenteric amebiasis (including amoebic abscess of a liver)
an infection giardiasis caused by anaerobic bacteria: a septicaemia, meningitis, peritonitis, abscesses in ophthalmology
postoperative infections in coloproctology, gynecology, surgery, maxillofacial surgery: an endometritis, septic abortion, suppurative processes after extraction of teeth, etc.
the peptic ulcer of a stomach and duodenum associated by H. Pylori
a bacterial vaginosis
prevention of mephitic gangrenes after surgical and gynecologic interventions
treatment of a demodicosis in dermatology and ophthalmology.
A route of administration and dozytabletka are accepted after a meal. At treatment of trichomoniasis at adults two schemes of combination therapy
the Course of treatment
1
scheme 2 the scheme
Single dose
of 1.5 g are applied (the 6th tab.) in
1 g (the 4th tab.) inside + 1 vaginal tab. (Ornisida) before going to bed
5 days
of 500 mg (the 2nd tab.) in the morning and 500 mg (the 2nd tab.) in the evening in
500 mg (the 2nd tab.) in the morning and 500 mg (the 2nd tab.) in the evening in + 1 vaginal a tab. (Ornisid) before going to bed
to Children a dose is established at the rate of 25 mg/kg of body weight/days. In amoebic dysentery to adults and children with body weight higher than 35 kg are appointed inside on 1.5 g (the 6th tab.) 1 time/days in the evening, adult with body weight more than 60 kg – 2g/days (the 4th tab. in the morning and the 4th tab. in the evening). To children with body weight less than 35 kg drug appoint 1 times/days from calculation 40mg/kg body weights. A course of treatment – 3 days. At other forms of an amebiasis to adults and children with body weight higher than 35 kg are appointed inside on 500 mg of 2 times/days (the 2nd tab. in the morning and the 2nd tab. in the evening). A course of treatment – 5-10 days. In a giardiasis to adults and children with body weight higher than 35 kg are appointed inside on 1.5 g (the 6th tab.) 1 time/days in the evening within 1-2 days, or on 500 mg of 2 times/days (the 2nd tab. in the morning and the 2nd tab. in the evening) within 5-10 days. To children with body weight less than 35 kg drug appoint 1 times/days at the rate of 40 mg/kg of body weight at reception within 1-2 days. For treatment of the infections caused by anaerobic bacteria, the adult appoint 500 mg of 2 times/days (the 2nd tab. in the morning and the 2nd tab. in the evening) within 5-10 days. The daily dose for children is established at the rate of 25 mg/kg of body weight. For prevention appoint 500 mg before operation and on 500 mg of 2 times/days after operation within 1-5 days.
Side effects
dyspepsia
allergic reactions (skin rash, an itching)
a polyuria
damage of central nervous system and peripheral nerves
of the Contraindication
of a disease of central nervous system
hypersensitivity to drug components
pregnancy.
Medicinal vzaimodeystviyapr combined use of Ornisid with other derivatives of the 5th nitroimidazole can be observed a peripheral neuropathy, a depression and epileptoformny spasms. Ornidazol does not inhibit an aldegiddegidrogenaza and therefore does not interact with alcohol. Simultaneous use with inductors of microsomal enzymes (barbiturates, benzodiazepines, rifampitsina, etc.) reduces a half-life period of an ornidazol in serum. Inhibitors of microsomal enzymes (Cimetidinum, macroleads, etc.) increase a half-life period of an ornidazol. Ornidazol strengthens action of anticoagulative means that demands correction of their dose. The combination of an ornisid with neurotoxic and gematotoksichny drugs is not recommended.
Special ukazaniyapr trichomoniasis it is necessary to carry out simultaneous treatment of the sexual partner in order to avoid repeated infection. Pregnancy and a laktatsiyaprimeneniye of drug at pregnancy (III trimester of pregnancy) and in the period of a lactation (breastfeeding) it is possible only after assessment advantage/risk. Influence of medicine on a posobnost to manage transport to the sredstvamena influences.
PeredozirovkaSimptoma: strengthening of manifestations of side effect. Treatment: antidote does not exist, carry out symptomatic therapy, in spasms appoint diazepam.
The form of release and an upakovkatabletka coated on 250 mg No. 10 in the blister (2х10), in cardboard packing.
Conditions to hraneniyakhranit at a temperature not above +30C. To store in places inaccessible for children!
godnosti2 to the godena to apply term after the expiration date specified on packing.
Prescription status from aptekpo to the prescription
the Trade name Ornisid
Mezhdunarodnoye unlicensed nazvaniyeornidazol (Ornidazol)
Medicinal formatabletka of 250 mg coated
SostavOdna a tablet soderzhitaktivny substance - ornidazol 250.00 mg, excipients: - microcrystalline cellulose, starch, methylhydroxyethyl cellulose, magnesium stearate. A cover - hydroksipropilmetit cellulose, talc, the titan OpisanieKruglye dioxide, biconvex, white or almost white tablets, coated, with risky on the one hand. Pharmacological svoystvaornisid (ornidazol) possesses antibacterial and antiprotozoan action. Interacting with DNA of a microbic cell, causes disturbance of its helical structure, a rupture of threads, suppresses synthesis of nucleic acids and causes death of microbic cells and cells of protozoa. Ornisid (ornidazol) is active concerning protozoa: Trichomonas vaginalis, Entamoeba histolitica, Gardnerella vaginalis. Giardia intestinalis, Lambilia. And also concerning anaerobic cocci: Peptostrepococcus, Peptococcus. Ornidazol is easily absorbed from digestive tract. Bioavailability – 90%. The maximum concentration in plasma is reached within 2 hours. After oral use of the maximum daily dose of 1.5 g the concentration of an ornidazol in blood plasma reaches 30mg/ml, on the expiration of 24 hours the plasma concentration goes down to 9mg/ml. Linking with blood proteins makes menee15%. Ornidazol well gets into all fabrics and liquids of an organism, including cerebrospinal liquid. Biotransformation of an ornidazol occurs in a liver. Elimination half-life of an ornidazol makes 12-14 hours. After single dose of 85% of a dose it is brought out of an organism within 5 days in the form of metabolites. Ornidazol is brought generally in the form of metabolites by kidneys (63%) and with excrement (22%). Elimination of an ornidazol is possible also in the bilious way.
Indications
trichomoniasis at women and men: mecotic vulvovaginitis, urethritis, bartholinitis, cervicitis, prostatitis, adnexitis, etc.
amebiasis: the amoebic dysentery, an abenteric amebiasis (including amoebic abscess of a liver)
an infection giardiasis caused by anaerobic bacteria: a septicaemia, meningitis, peritonitis, abscesses in ophthalmology
postoperative infections in coloproctology, gynecology, surgery, maxillofacial surgery: an endometritis, septic abortion, suppurative processes after extraction of teeth, etc.
the peptic ulcer of a stomach and duodenum associated by H. Pylori
a bacterial vaginosis
prevention of mephitic gangrenes after surgical and gynecologic interventions
treatment of a demodicosis in dermatology and ophthalmology.
A route of administration and dozytabletka are accepted after a meal. At treatment of trichomoniasis at adults two schemes of combination therapy
the Course of treatment
1
scheme 2 the scheme
Single dose
of 1.5 g are applied (the 6th tab.) in
1 g (the 4th tab.) inside + 1 vaginal tab. (Ornisida) before going to bed
5 days
of 500 mg (the 2nd tab.) in the morning and 500 mg (the 2nd tab.) in the evening in
500 mg (the 2nd tab.) in the morning and 500 mg (the 2nd tab.) in the evening in + 1 vaginal a tab. (Ornisid) before going to bed
to Children a dose is established at the rate of 25 mg/kg of body weight/days. In amoebic dysentery to adults and children with body weight higher than 35 kg are appointed inside on 1.5 g (the 6th tab.) 1 time/days in the evening, adult with body weight more than 60 kg – 2g/days (the 4th tab. in the morning and the 4th tab. in the evening). To children with body weight less than 35 kg drug appoint 1 times/days from calculation 40mg/kg body weights. A course of treatment – 3 days. At other forms of an amebiasis to adults and children with body weight higher than 35 kg are appointed inside on 500 mg of 2 times/days (the 2nd tab. in the morning and the 2nd tab. in the evening). A course of treatment – 5-10 days. In a giardiasis to adults and children with body weight higher than 35 kg are appointed inside on 1.5 g (the 6th tab.) 1 time/days in the evening within 1-2 days, or on 500 mg of 2 times/days (the 2nd tab. in the morning and the 2nd tab. in the evening) within 5-10 days. To children with body weight less than 35 kg drug appoint 1 times/days at the rate of 40 mg/kg of body weight at reception within 1-2 days. For treatment of the infections caused by anaerobic bacteria, the adult appoint 500 mg of 2 times/days (the 2nd tab. in the morning and the 2nd tab. in the evening) within 5-10 days. The daily dose for children is established at the rate of 25 mg/kg of body weight. For prevention appoint 500 mg before operation and on 500 mg of 2 times/days after operation within 1-5 days.
Side effects
dyspepsia
allergic reactions (skin rash, an itching)
a polyuria
damage of central nervous system and peripheral nerves
of the Contraindication
of a disease of central nervous system
hypersensitivity to drug components
pregnancy.
Medicinal vzaimodeystviyapr combined use of Ornisid with other derivatives of the 5th nitroimidazole can be observed a peripheral neuropathy, a depression and epileptoformny spasms. Ornidazol does not inhibit an aldegiddegidrogenaza and therefore does not interact with alcohol. Simultaneous use with inductors of microsomal enzymes (barbiturates, benzodiazepines, rifampitsina, etc.) reduces a half-life period of an ornidazol in serum. Inhibitors of microsomal enzymes (Cimetidinum, macroleads, etc.) increase a half-life period of an ornidazol. Ornidazol strengthens action of anticoagulative means that demands correction of their dose. The combination of an ornisid with neurotoxic and gematotoksichny drugs is not recommended.
Special ukazaniyapr trichomoniasis it is necessary to carry out simultaneous treatment of the sexual partner in order to avoid repeated infection. Pregnancy and a laktatsiyaprimeneniye of drug at pregnancy (III trimester of pregnancy) and in the period of a lactation (breastfeeding) it is possible only after assessment advantage/risk. Influence of medicine on a posobnost to manage transport to the sredstvamena influences.
PeredozirovkaSimptoma: strengthening of manifestations of side effect. Treatment: antidote does not exist, carry out symptomatic therapy, in spasms appoint diazepam.
The form of release and an upakovkatabletka coated on 250 mg No. 10 in the blister (2х10), in cardboard packing.
Conditions to hraneniyakhranit at a temperature not above +30C. To store in places inaccessible for children!
godnosti2 to the godena to apply term after the expiration date specified on packing.
Prescription status from aptekpo to the prescription
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