Orniksil (30 tablets)

Orniksil No. 30 of a tablet contains In each tablet: Ornithine of 200 mg Silmmarin of 70 mg Artichoke of 200 mg Pharmacotherapeutic group: Gepatoprotektor, dezintoksikant, hypoazotemic, gipoammoniyemichesky, bile-expelling, diuretic. Pharmacological properties: Ornithine renders disintoxication, hypoazotemic, gepatoprotektivny, gipoammoniyemichesky action. Utilizes ammonium groups in urea synthesis (ornitinovy cycle). Reduces concentration of ammonia in blood plasma, contributes to normalization of the acid-base state (ABS) of blood, at the same time improves solubility of salts and accelerates their discharges with urine. Ornithine uslllva9an ornitinovy cycle, accelerates utilization of organic complexes of nitrogen to urea and reduces synthesis of uric acid. Ornithine reducing synthesis of uric acid interferes with formation of a nephrolithiasis. And also ornithine Ana and STG stimulates development shsul. At intake, aspartate dissociates ornithine on the components (ornithine and aspartate) making it which are soaked up in a small intestine by active transport through an intestinal epithelium. Silymarinum the containing complex flavonoidnykh-the connections received from a thistle spotty is removed with urine through a mochevinoobrazovaniye cycle. Silymarinum has the regenerating, disintoxication, gepatoprotektivny and anti-inflammatory effect. The mechanism of effect of drug is connected with its ability to activate synthesis of vital proteins and phospholipids in hepatocytes, due to stimulation of a RNA polymerase. Silymarinum possesses the significant antioxidant action, promotes protection of cells against negative impact of free radicals and peroxide connections. The antioxidant effect of drug is carried out due to existence in molecules of flavonoids of phenolic structure which takes part in binding of free radicals. Thus, there is an inhibition of processes of peroxide oxidation of lipids in hepatocytes that promotes maintaining cellular structures and their fastest regeneration. Drug not only reduces intensity of formation of a malonaldegid, but also regulates oxygen absorption by cells. Drug enhances disintoxication activity of a liver due to increase in an accumulation glugat bosoms. In a drunkenness drug reduces formation of ethyl aldehyde. Silymarinum assesses with the significant membrane stabilizing action, due to biochemical interaction with cellular membranes drug prevents loss of the substances which are contained in a cell and improves exchange processes. The artichoke has bile-expelling, hepatoprotective and diuretic effects. Also promotes reduction of level of urea in blood sera. Drug increases ability of hepatocytes to produce coenzymes that improves cholesterol exchange, llplr, ov and metabolism of ketone bodies. At accompanying antlb) lotlkoterapl/affects a parenchyma of kidneys and a liver as disintoxication means. The inulin and vitamins of group B (B2, B1) entering the list of biologically active agents of an artichoke normalize exchange processes in an organism. Drug promotes clarification of an organism from toxins, including nitro compounds, salts of heavy metals and alkaloids. It is recommended to accept: Drug is used in complex treatment of diseases of a liver, gall bladder and kidneys of various etiology, including: Chronic viral hepatitis. Therapy of patients with a podosuey, persistent and active chronic form of a viral hepatitis. The rehabilitation period after the postponed acute form of a viral hepatitis. The damages of a liver connected with lipometabolism disturbance including a steatosis (fat hepatosis) and fat dystrophy of a liver. Cirrhosis of various etiology. Drug is used also in complex therapy of patients with disturbances of lipidic and cholesteric exchange. Hepatic encephalopathy. Acute and chronic cholecystitis, cholangitis, hypokinetic option of dyskinesia of biliary tract. Drug is used also in complex therapy at patients with a nephrolithiasis. Medicinal damages of a liver and the period of administration of drugs, having hepatotoxic properties: Poisonings with the halogenated hydrocarbons and heavy metals. Poisonings with solvents of organic origin. The damages of a liver connected with alcohol intake including at the patients having an alcoholism and in acute poisonings with alcohol. Route of administration and doses: At free use by the consumer, it is recommended to respect the rules specified on packing. If drug is appointed by the doctor, changes in a dosage are possible: on one tablet 1-2 times a day, inside, after a meal. Side effects: Seldom skin reactions, nausea and vomiting are in some cases possible. Contraindications: The profound renal failure (at creatinine level in plasma more Zmg/100ml), hypersensitivity to drug components. Overdose: Strengthening of symptoms of side effects. Treatment: gastric lavage, intake of activated carbon, symptomatic therapy. Packaging: Orniksil N30. On 2 blisters on 15 tablets with a leaf insert in cardboard packing. Expiration date: Specified on packing and blisters. Not to apply after expiry date! USLOVIYAUSLOVIYA storages: At a temperature not above 20 °C. Out of children's reach! PRESCRIPTION STATUS: Without prescription. The owner of a product and trademark is the NOVATOR PHARMA company Great Britain. Office 21.8 Shepherd Market London, WD 7JY, UK. 147-157 St John Street EC IV 4PY, London, Great Britain are made in PRIMEA LIMITED.