Omnadren® 250 (Testosterone blend), 5 x 250 mg/1 ml

Common brand names: Androderm, Delatestryl, Striant, Testo-100, Vogelxo, Axiron, Nebido, Sustanon, Testoderm, Testogel, Testopel Pellets, Virormone

What Is Omnadren® 250 (Testosterone Blend)?

Omnadren® 250 is a testosterone replacement therapy formulated for men diagnosed with hypogonadism—a condition characterized by insufficient testosterone production.

Each ampule contains 250 mg of a unique blend of testosterone esters, designed for intramuscular injection.

This blend ensures a gradual release of testosterone, providing stable hormone levels and long-lasting effects.

Omnadren® 250 helps restore hormonal balance, improving physical performance, energy, libido, and overall quality of life.

What Are the Uses of Omnadren® 250?

Key Indications

• Primary hypogonadism: A condition due to testicular failure, resulting in low testosterone levels.
• Secondary hypogonadism: A result of hypothalamic or pituitary dysfunction affecting testosterone production.
• Omnadren® 250 is prescribed for adult men experiencing symptoms such as reduced libido, fatigue, muscle loss, and depression caused by low testosterone levels.

How Does Omnadren® 250 Work?

Omnadren® 250 combines four testosterone esters: testosterone propionate, phenylpropionate, isocaproate, and decanoate. This unique blend ensures that testosterone is released at varying rates into the bloodstream:

• Immediate effect: Testosterone propionate acts quickly after injection.
• Sustained release: The other esters provide a steady release over a three-week period, ensuring prolonged therapeutic benefits and reducing the frequency of injections.

Why Is Omnadren® 250 Recommended?

Omnadren® 250 offers an effective and convenient testosterone replacement solution for men with low testosterone levels.

Its unique blend of esters ensures steady hormonal support over several weeks, reducing the need for frequent dosing.

By addressing symptoms of androgen deficiency, it helps restore energy, strength, libido, and overall well-being.

Regular medical supervision ensures safe use and minimizes risks.

How Should You Use Omnadren® 250?

Recommended Dosage

• The usual dosage is 1 ampule (250 mg) administered every 3 weeks.
• The dosage may be adjusted based on testosterone levels, symptoms, and response to treatment as monitored by a healthcare provider.

Method of Administration

• Administer via deep intramuscular injection into the gluteal muscle.
• It is crucial that injections are performed by a trained healthcare professional to avoid complications like injection site pain or nerve injury.

Duration of Treatment

• The treatment duration depends on individual needs and the underlying cause of hypogonadism. Regular follow-ups with a healthcare provider ensure optimal outcomes and dosage adjustments as needed.

What Precautions Should Be Taken?

Before Using Omnadren® 250

• Contraindications:

  • Allergies to testosterone or ingredients (e.g., peanut oil).
  • Prostate or breast cancer, confirmed or suspected.
  • Severe liver or kidney impairment, as testosterone may exacerbate these conditions.
  • Heart failure or a history of myocardial infarction.
  • Prepubertal boys and elderly men with fragile health are generally not candidates for this therapy.

• Monitoring Requirements:

  • Testosterone levels should be measured before starting therapy and regularly during treatment.
  • Prostate health must be closely monitored, including PSA tests and physical exams.
  • Blood parameters, such as hemoglobin and hematocrit, should be checked to prevent complications like polycythemia.

• Warnings:

  • Use caution in men with hypertension, as testosterone may increase blood pressure.
  • Testosterone therapy may lead to fluid retention, worsening conditions like heart failure or kidney dysfunction.
  • Long-term use requires regular monitoring for potential side effects, including liver toxicity and prostate health issues.

Are There Any Side Effects?

Common Side Effects

• Injection site reactions: Pain, redness, or swelling at the injection site.
• Hormonal effects: Increased libido, acne, oily skin, or gynecomastia (breast tissue enlargement in men).
• Weight changes: Possible weight gain due to increased muscle mass or fluid retention.

Serious Side Effects

• Prostate complications: Risk of benign prostatic hyperplasia (BPH) or progression of subclinical prostate cancer.
• Liver issues: Rare cases of liver toxicity, hepatic tumors, or jaundice, especially with long-term use.
• Cardiovascular risks: Hypertension, fluid retention, and potential exacerbation of heart conditions.
• Mood and behavior changes: Depression, aggression, or mood swings may occur in some patients.

Rare Risks

• Polycythemia: Elevated red blood cell count, which can increase the risk of blood clots.
• Priapism: Prolonged, painful erections requiring immediate medical attention.
• Allergic reactions: Patients with peanut or soy allergies may experience severe reactions due to the presence of peanut oil in the formulation.

How Should Omnadren® 250 Be Stored?

• Store in a cool, dry place at temperatures below 25°C (77°F).
• Protect from light and avoid freezing.
• Keep out of reach of children and discard after the expiration date.