Oksivin-DF 0,025% 10ml nasal spray

  • $4.00
Sku: 8001907b69b2
Ingredient: Oxymetazoline
The trade name
of Oksivin-DF

the International unlicensed

name Oxymetazoline Dosage Form Spray of Nasal 0.025%, 0.05% 10 ml

of 1 ml of drug contains
active agent - oxymetazoline a hydrochloride - 0.25 mg or 0.5 mg
excipients: a benzalkoniya chloride (in the form of 10% of solution), sodium chloride, dihydrophosphate sodium a dihydrate, phosphate dinatrium dodecahydrate, water

the Pharmacotherapeutic group cleaned the Description Transparent colourless or slightly yellowish solution
Nasal drugs. Antikongestanta and other nasal drugs for topical administration. Sympathomimetics. Oxymetazoline
the ATX R01AA05 Code

the Pharmacological

Pharmacokinetics At properties topical administration oxymetazoline in a small amount is soaked up in a system blood stream therefore its concentration in blood plasma is insignificant. Effect of drug is shown in 15 min. after use. Action duration - 10-12 h.
Drug is metabolized only in moderate degree and generally removed from an organism in an invariable view with urine and a stake.
The pharmacodynamics
Oksimetazolin is alpha adrenomimetikom from group of derivatives of imidazoline. Stimulates α1-адренорецепторы. At intranasal use there is a narrowing of blood vessels of a mucous membrane of a nose, hypostasis and hyperaemia of a mucous membrane of a nasopharynx is eliminated. After removal of hypostasis of a mucous membrane the removing channels for aeration of adnexal bosoms of a nose, an acoustical pipe open and extend. It stimulates drainage function of nasal cavities and prevents development of bacterial complications.

- acute, allergic, vasomotorial rhinitis
- rinosinusit
- the eustachitis associated by rhinitis
- elimination of hypostasis of a mucous membrane of a nasal cavity before the diagnostic

Route of administration procedures and
Intranazalno's doses.
In order that it is correct to make injection, it is necessary to remove a protective cap, to press carefully a plastic tip spray of 1 - 2 time that solution arrived to the spray and it was sprayed. Then the nozzle of a bottle should be placed in the nasal course, quickly and sharply to press 1 time on the spray and to take out a nozzle, without unclenching the spray.
0.025% spray nasal to children from 1 year to 6 years: on 1 injection in each nasal course 2-3 times a day.
0.05% spray nasal to children are more senior than 6 years and the adult: on 1 injection in each nasal course 2-3 times a day.
Course of treatment no more than 5-7 days.

Side effects
- burning and dryness mucous the nasal courses
- dryness in a mouth and a throat
- sneezing
- dizziness, a headache
- insomnia
- fatigue (fatigue)
- nausea
- swelling and hypostasis of a mucous membrane (feeling of congestion of a nose)
- a reactive hyperemia
- a mucosal atrophy
- allergic reactions (Quincke's edema, urticaria, an itching)
is very rare:
- increase of pulse
- arterial hypertension
- tachycardia

the Contraindication tachyphylaxis
- hypersensitivity to drug components
- atrophic rhinitis
- the profound atherosclerosis
- chronic heart failure
- arrhythmias
- arterial hypertension
- chronic kidney disease
- a prostate hyperplasia
- a concomitant use of inhibitors of a monoaminooxidase and the period up to 14 days after the end of their use
- diabetes
- a thyrotoxicosis, a hyperthyroidism
- closed-angle glaucoma
- a serious illness of eyes
- a pheochromocytoma
- a porphyria
- children's age till 1 year (for Oksivin-DF of 0.025%)
- children's age up to 6 years (for Oksivin-DF of 0.05%)

Medicinal interactions
Drug slows down absorption of mestnoanesteziruyushchy means and prolongs their effect.
At use of Oksivina-DF with other vasoconstrictors (irrespective of a method of administration) perhaps mutual strengthening of side effects.
Co-administration of inhibitors of a monoaminooxidase (including the period within 14 days after their cancellation) and tricyclic antidepressants can lead to increase in arterial blood pressure.

Special instructions
It is necessary to avoid prolonged use of Oksivina-DF as it can lead to weakening of its therapeutic action.
It is not necessary to exceed independently recommended doses and to use drug more than 5 - 7 days.
To apply with care in the coronary heart disease (CHD).
Pregnancy and the period of a lactation
is not recommended in connection with insufficient experience of use.
Use of drug at pregnancy and in the period of a lactation perhaps only when the expected advantage for mother exceeds potential risk for the child and a fruit.
The feature of influence of medicine on ability to run the vehicle or potentially dangerous mechanisms
In the recommended doses of Oksivin-DF does not affect ability to run the vehicle or work with mechanisms.

Symptoms: when exceeding the recommended doses or accidental intake the following symptoms can appear: narrowing of pupils, nausea, vomiting, cyanosis, temperature increase, tachycardia, arrhythmia, collapse, oppression of warm activity, arterial hypertension, fluid lungs, respiratory disorders. Besides, there can be mental disorders and also the oppression of functions of the central nervous system which is followed by drowsiness, fall of temperature of a body, bradycardia, arterial hypotension, an apnoea and possible development of a coma.
Treatment: immediately appoint activated carbon (absorbent), sodium sulfate (depletive) or gastric lavage. For a lowering of arterial pressure appoint non-selective alpha adrenoblockers (phentolamine of 5 mg in saline (physiological) solution slowly in/in or 100 mg orally). Use of angiotonic means is contraindicated.
If necessary carry out febrifugal, anticonvulsant therapy and artificial ventilation of the lungs.

A form of release and packing
On 10 ml of drug in plastic brown bottles with the pompovy portioning device including aluminum zavaltso-vyvayushchuyusya a cover with a submersible tube and a plastic tip spray with a protective cap. On each bottle paste the label. On one bottle together with the instruction for medical use in the state and Russian languages place in a pack cardboard.

To Store storage conditions in the place protected from light, at a temperature not over 25 of 0C.
To store out of children's reach!

3 years
not to apply a period of storage after an expiration date.

Prescription status
Without prescription
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