Nimid 30g of gel for topical application

  • $7.20
Sku: b4263831202f
Ingredient: Nimesulide
NimidTM


the Trade name
NimidTM

Mezhdunarodnoye the unlicensed



name Nimesulide Dosage Form Gel for external use of 30 g and 100 g
Structure
of 1 g of gel contains
active agent - the Nimesulide (micronized) of 10 mg,
excipients: propylene glycol, karbopol 980 (carbomer 940), dinatrium edetat, methylparahydroxybenzoate, propilparagidroksibenzoat, sodium hydroxide, Cologne Comp 530 fragrance **, the water purified.
**-Sostav: limonene, linalyl ester, linalit acetate, geraniol, lavendinat, cyclamen aldehyde, methyl ionone, liliat, beta naphthylmethylketone, an alpha - amylcinnamic aldehyde, vertofix.

Description
Opaque, uniform gel of light yellow color.

Pharmacotherapeutic group
Non-steroidal anti-inflammatory drugs for topical administration.
The code of automatic telephone exchange M02AA

the Pharmacological

Pharmacokinetics At properties putting Nimesulide of gel on skin, levels of concentration of drug in blood plasma very low, in comparison with the concentration reached at administration of drug it is oral. After single use of 200 mg of Nimesulide, in the form of gel, the registered highest level of concentration in blood plasma is 9.77 ng/ml 24 hours later. In the established state (8 days) the peak concentration in plasma increases (37.25 ± 13.25 ng/ml), but is anyway 100 times lower than the concentration reached as a result of repeated reception oral

NimidTM dosed the Pharmacodynamics gel is nonsteroid, anti-inflammatory drug (NPVP) for topical administration.
Renders expressed the anti-inflammatory, anesthetizing and moderate febrifugal action. Action mechanism: oppressing cyclooxygenase, influences metabolism of arachidonic acid, reducing amount of prostaglandins in the center of inflammation participating in forming of hypostasis and pain at inflammation.

Indications
- the pain syndrome connected with sprain and an acute
traumatic tendinitis (symptomatic therapy)

the Route of administration and doses
NimidTM apply gel outwardly. 3 g of drug (6-7 cm of the gel which is forced out from a tuba) apply to skin a thin layer on an affected area 2-3 times a day, easy massage movements rub before full absorption. Duration of a course of treatment is 7-15 days.

Side effects
- irritation of skin, an erythema, skin rash, peeling, an itching on the site of application of gel, tranzitorny discoloration of skin.

The contraindication
- the known hypersensitivity to Nimesulide or any
auxiliary components of drug
- allergic reactions (bronchospasm, rhinitis, a small tortoiseshell) to
acetylsalicylic acid or other
non-steroidal anti-inflammatory drugs (in the anamnesis)
- use of gel on open wounds or in the presence of a local infection
- simultaneous use with other creams
- children's and teenage age up to 18 years (safety and efficiency
of drug is not studied)

Medicinal interactions
Quantity of significant vzaymodeystviye with other medicines at topical administration of Nimid gel is noted.

The special
instructions NimidTM gel should not be applied on open wounds and cuts of skin.
It is necessary to avoid hit of drug in eyes, on mucous membranes. In case of accidental contact, it is necessary to wash with water immediately.
Not to use drug inside.
After drawing it is necessary to wash up hands.
After imposing it is not necessary to apply an occlusive bandage.
The risk of side reactions can be reduced by drawing the minimum dose during the short span.
It is necessary to appoint drug with care the patient with a severe form of a liver and renal failure, disturbance of fibrillation and heart failure.
In order to avoid reactions of photosensitivity, patients should avoid long influence of direct sunshine.
In case improvements are not observed or if the state on the contrary worsened, treatment it is necessary to stop and see a doctor.
Pregnancy and the period of a lactation
of Experience of use of drug during pregnancy and breastfeeding are not present. Therefore, during pregnancy and a lactation drug can be appointed, only if the potential advantage exceeds potential risk for a fruit.
Features of influence of medicine on ability to run the vehicle or by potentially dangerous mechanisms
it is not studied.

The overdose
As drug of topical administration, at the correct use, exists the small probability of systematic adsorption, i.e. overdose.

A form of release and packing
On 30 g (for packing of 30 g) or 100 g (for packing of 100 g) gel in aluminum tubas with the white screw-on covers.
Each tuba together with the instruction for medical use in the state and Russian languages is put in a pack from cardboard.


To Store storage conditions in the place protected from light at a temperature not over 250C.
Not to freeze.
To store out of children's reach!


2 years
not to use a period of storage after the expiry date specified on packing

Prescription status
Without prescription


the Producer Kusum Heltker Pvt. Ltd., India
Bkhagat Singh Marg, New Delhi 110001
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