Nemozole (Albendazole) 400 mg, 1 tablet

What is Nemozole (Albendazole) 400 mg?

Nemozole is an antiparasitic medication containing 400 mg of Albendazole, used to treat a variety of parasitic infections.

It is effective against both intestinal and systemic parasites.

Albendazole works by inhibiting the parasites' ability to absorb glucose, leading to their eventual death.

This medication is commonly prescribed for conditions like pinworm infection (enterobiasis), roundworm infection (ascariasis), hookworm infections, and others.

How should Nemozole 400 mg be taken?

Nemozole 400 mg should be taken orally with food to improve absorption.

The tablet should be swallowed whole with water.

In cases where swallowing is difficult, the tablet may be chewed or crushed.

The dosage and duration of treatment vary depending on the type of parasitic infection.

For example:

• Enterobiasis (pinworm infection): A single dose of 400 mg is typically sufficient, but it may need to be repeated after 7 days.
• Ascariasis, Hookworm Infections: A single dose of 400 mg is generally prescribed.
• Strongyloidiasis or Taeniasis: 400 mg daily for 3 days.
• Giardiasis in children: 400 mg daily for 5 days.
• Trichinosis (systemic infection): 400 mg twice daily for 10-15 days.

Always follow your doctor's specific instructions regarding dosage and treatment duration.

What precautions should be taken before using Nemozole?

Before starting treatment with Nemozole, certain precautions should be observed:

• Liver Function: Albendazole may cause an increase in liver enzymes. Liver function should be monitored before and during treatment, especially if you have a history of liver disease. If significant liver enzyme elevation occurs, discontinuation of the medication may be necessary.
• Blood Counts: Albendazole can suppress bone marrow function, leading to low blood counts. Regular blood tests are recommended to monitor these levels, particularly during prolonged treatment.
• Pregnancy: Nemozole should not be used during pregnancy due to the risk of harm to the fetus. Women of childbearing age should use effective contraception during treatment and for one month after the last dose.
• Breastfeeding: Albendazole passes into breast milk. Breastfeeding should be discontinued during treatment and for at least 48 hours after the last dose.

What are the possible side effects of Nemozole?

While Nemozole is generally well-tolerated, it may cause some side effects.

These can vary depending on the duration and dosage of the treatment:

• Common side effects: Headache, dizziness, and gastrointestinal symptoms such as abdominal pain, nausea, and vomiting.
• Less common but severe effects: Allergic reactions like rash, itching, liver function abnormalities, and bone marrow suppression (which may lead to conditions like aplastic anemia or leukopenia).
• Rare effects: Stevens-Johnson syndrome (a severe skin reaction) and other hypersensitivity reactions.

If you experience any severe or unusual symptoms, seek medical attention immediately.

Can Nemozole interact with other medications?

Yes, Nemozole can interact with other medications. It may induce liver enzymes, affecting the metabolism of certain drugs.

Here are some notable interactions:

• Antiepileptic drugs: Such as phenytoin, carbamazepine, or phenobarbital may reduce the effectiveness of Albendazole.
• Cimetidine, Dexamethasone, Praziquantel: These drugs can increase the levels of Albendazole in the body, potentially leading to increased side effects.
• Grapefruit juice: Can also increase Albendazole levels, so it should be avoided during treatment.

Always inform your doctor of all the medications you are currently taking to avoid potential interactions.

How should Nemozole be stored?

Store Nemozole in a dry place, protected from light, at a temperature not exceeding 25°C (77°F).

Keep it out of reach of children and do not use it beyond the expiration date indicated on the package.