Mukeks 30 mg (20 tablets)
- $4.20
Trade name
of Mukex
the International unlicensed
name Ambroxol Dosage Form
of the Tablet, 30 mg
Structure
One tablet contains
active agent – Ambroxol a hydrochloride of 30 mg,
excipients: silicon dioxide colloidal anhydrous, sodium of a kroskarmelloz, cellulose microcrystalline, magnesium stearate
the Description
of the Tablet of white color, round, with risky on one party.
Pharmacotherapeutic group
Drugs for elimination of symptoms of cold and cough. Expectorant drugs. Mucolytics. Ambroxol
the ATX R05C B06 Code
the Pharmacological
Pharmacokinetics Absorption properties high, Tmax - 2 h, communication with proteins of plasma – 80%. Gets through a blood-brain barrier, a placental barrier, it is allocated with breast milk. After intake the action comes in 30 min. and continues during 6-12 h.
Metabolism - in a liver, forms dibromantranilovy acid and glucuronic conjugates. T½ - 7-12 h. It is removed by kidneys: 90% in the form of water-soluble metabolites, in not changed look – 5%. T½ increases in heavy chronic kidney disease, does not change in an abnormal liver function.
The pharmacodynamics
Mucolytic means, possesses sekretomotorny, sekretolitichesky and expectorant action, stimulates formation of surfactant, normalizes the changed bronchopulmonary secretion, improves rheological indicators of a phlegm, reduces its viscosity and adhesive properties, increases mukotsiliarny transport, facilitates removal of a phlegm from bronchial tubes. Increases physical activity of a ciliary epithelium, increases mukotsiliarny transport.
Indications
- sekretolitichesky therapy of the acute and chronic bronchopulmonary diseases which are characterized by disturbance of secretion and the complicated phlegm otkhozhdeniye
the Route of administration and doses
Adults and children are more senior than 12 years: on 1 tablet 3 times a day.
A pill should be taken after a meal and to wash down with water. Treatment duration without medical observation no more than 4 - 5 days.
If the state did not improve at the carried-out therapy of acute respiratory diseases to the patient it is necessary to see a doctor.
In the presence of diseases of kidneys or a liver (see the section Special Instructions).
Side effects
Gastrointestinal disorders
Often (≥ 1/100 - & lt, 1/10):
nausea, change of taste, decrease in sensitivity in an oral cavity and a throat (oral and pharyngeal giposteziya)
Infrequently (≥ 1/1.000 - & lt, 1/100):
vomiting, diarrhea, dyspepsia, an abdominal pain, dryness in a mouth
it is rare (≥ 1/10.000 - & lt, 1/1.000):
dryness in a throat
of Disturbance of the immune system
it is not known:
anaphylactic reactions, including an acute anaphylaxis
of Disturbance of skin and hypodermic cellulose
Seldom (≥ 1/10.000 - & lt, 1/1.000):
rash, urticaria,
it is not known:
itching and other reactions of hypersensitivity, Quincke's disease.
Contraindications
- hypersensitivity to Ambroxol to a hydrochloride and/or to other components of drug
- pregnancy and the period of a lactation
- children's age up to 12 years
- the peptic ulcer of a stomach and duodenum
Medicinal interactions
leads Combined use with antibechic medicines to difficulty of an otkhozhdeniye of a phlegm against the background of reduction of cough.
Use together with antibiotics (amoxicillin, tsefuroksy, erythromycin, doxycycline) leads to formation of high concentrations of antibiotics in tissues of lungs.
Special instructions
In a renal failure and/or a serious illness of a liver the decrease in a daily dose and increase in an interval between administration of drug is necessary, it is necessary to use drug with extra care.
Very exceptional cases of severe damages of skin such as Stephens-Johnson's syndrome and toxic epidermal necrolysis are registered at hydrochloride Ambroxol use. Mainly they are caused by weight of a basic disease and the accompanying treatment, in that case administration of drug stops.
The feature of influence of medicine on ability to run the vehicle or potentially dangerous mechanisms
does not influence.
Overdose
Symptoms: nausea, vomiting, dyspepsia, the increased drowsiness, excitement, the raised sialosis.
Treatment: artificial vomiting, gastric lavage in the first 1-2 h after administration of drug, reception of fat-containing products. Symptomatic therapy.
The form of release and packing
On 10 tablets place in blister strip packaging from a film of polyvinylchloride/polyvinyldichloride and aluminum foil.
On 2 or 10 blister strip packagings together with the instruction for medical use in the state and Russian languages place in a pack cardboard.
To Store storage conditions in the dry, protected from light place, at a temperature not over 25 ºС.
To store out of children's reach!
A period of storage
3 years
Prescription status
Without prescription
of Mukex
the International unlicensed
name Ambroxol Dosage Form
of the Tablet, 30 mg
Structure
One tablet contains
active agent – Ambroxol a hydrochloride of 30 mg,
excipients: silicon dioxide colloidal anhydrous, sodium of a kroskarmelloz, cellulose microcrystalline, magnesium stearate
the Description
of the Tablet of white color, round, with risky on one party.
Pharmacotherapeutic group
Drugs for elimination of symptoms of cold and cough. Expectorant drugs. Mucolytics. Ambroxol
the ATX R05C B06 Code
the Pharmacological
Pharmacokinetics Absorption properties high, Tmax - 2 h, communication with proteins of plasma – 80%. Gets through a blood-brain barrier, a placental barrier, it is allocated with breast milk. After intake the action comes in 30 min. and continues during 6-12 h.
Metabolism - in a liver, forms dibromantranilovy acid and glucuronic conjugates. T½ - 7-12 h. It is removed by kidneys: 90% in the form of water-soluble metabolites, in not changed look – 5%. T½ increases in heavy chronic kidney disease, does not change in an abnormal liver function.
The pharmacodynamics
Mucolytic means, possesses sekretomotorny, sekretolitichesky and expectorant action, stimulates formation of surfactant, normalizes the changed bronchopulmonary secretion, improves rheological indicators of a phlegm, reduces its viscosity and adhesive properties, increases mukotsiliarny transport, facilitates removal of a phlegm from bronchial tubes. Increases physical activity of a ciliary epithelium, increases mukotsiliarny transport.
Indications
- sekretolitichesky therapy of the acute and chronic bronchopulmonary diseases which are characterized by disturbance of secretion and the complicated phlegm otkhozhdeniye
the Route of administration and doses
Adults and children are more senior than 12 years: on 1 tablet 3 times a day.
A pill should be taken after a meal and to wash down with water. Treatment duration without medical observation no more than 4 - 5 days.
If the state did not improve at the carried-out therapy of acute respiratory diseases to the patient it is necessary to see a doctor.
In the presence of diseases of kidneys or a liver (see the section Special Instructions).
Side effects
Gastrointestinal disorders
Often (≥ 1/100 - & lt, 1/10):
nausea, change of taste, decrease in sensitivity in an oral cavity and a throat (oral and pharyngeal giposteziya)
Infrequently (≥ 1/1.000 - & lt, 1/100):
vomiting, diarrhea, dyspepsia, an abdominal pain, dryness in a mouth
it is rare (≥ 1/10.000 - & lt, 1/1.000):
dryness in a throat
of Disturbance of the immune system
it is not known:
anaphylactic reactions, including an acute anaphylaxis
of Disturbance of skin and hypodermic cellulose
Seldom (≥ 1/10.000 - & lt, 1/1.000):
rash, urticaria,
it is not known:
itching and other reactions of hypersensitivity, Quincke's disease.
Contraindications
- hypersensitivity to Ambroxol to a hydrochloride and/or to other components of drug
- pregnancy and the period of a lactation
- children's age up to 12 years
- the peptic ulcer of a stomach and duodenum
Medicinal interactions
leads Combined use with antibechic medicines to difficulty of an otkhozhdeniye of a phlegm against the background of reduction of cough.
Use together with antibiotics (amoxicillin, tsefuroksy, erythromycin, doxycycline) leads to formation of high concentrations of antibiotics in tissues of lungs.
Special instructions
In a renal failure and/or a serious illness of a liver the decrease in a daily dose and increase in an interval between administration of drug is necessary, it is necessary to use drug with extra care.
Very exceptional cases of severe damages of skin such as Stephens-Johnson's syndrome and toxic epidermal necrolysis are registered at hydrochloride Ambroxol use. Mainly they are caused by weight of a basic disease and the accompanying treatment, in that case administration of drug stops.
The feature of influence of medicine on ability to run the vehicle or potentially dangerous mechanisms
does not influence.
Overdose
Symptoms: nausea, vomiting, dyspepsia, the increased drowsiness, excitement, the raised sialosis.
Treatment: artificial vomiting, gastric lavage in the first 1-2 h after administration of drug, reception of fat-containing products. Symptomatic therapy.
The form of release and packing
On 10 tablets place in blister strip packaging from a film of polyvinylchloride/polyvinyldichloride and aluminum foil.
On 2 or 10 blister strip packagings together with the instruction for medical use in the state and Russian languages place in a pack cardboard.
To Store storage conditions in the dry, protected from light place, at a temperature not over 25 ºС.
To store out of children's reach!
A period of storage
3 years
Prescription status
Without prescription
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