Metronidazole 500 mg, 10 vaginal suppositories

What is Metronidazole 500 mg Vaginal Suppository?

Metronidazole 500 mg vaginal suppositories are a form of medication used to treat various infections within the vaginal area.

This medicine works by targeting specific bacteria, helping to clear infections such as bacterial vaginosis and certain sexually transmitted infections like trichomoniasis.

The suppository is designed for easy insertion into the vagina, ensuring that the medication acts directly where it is needed most.

How does Metronidazole work?

Metronidazole belongs to a group of medicines called nitroimidazoles, which work by inhibiting the growth of bacteria and parasites.

This antibiotic is especially effective in treating anaerobic infections—those caused by bacteria that do not require oxygen to grow.

By stopping the production of proteins that bacteria need to multiply, metronidazole helps the body eliminate infections more effectively.

What infections are treated with Metronidazole vaginal suppositories?

Metronidazole vaginal suppositories are prescribed to treat the following conditions:

• Trichomoniasis: A sexually transmitted infection caused by the parasite Trichomonas vaginalis.
• Bacterial vaginosis: A common vaginal infection resulting from an imbalance in normal bacteria.
• Other anaerobic infections: These include various bacterial infections of the vagina that are sensitive to metronidazole.

How should I use Metronidazole vaginal suppositories?

It is essential to follow the prescribed dosage for metronidazole vaginal suppositories to ensure effective treatment.

Generally, one suppository is inserted into the vagina once a day, preferably before bedtime, for 10 consecutive days.

Ensure that you continue the treatment even after symptoms subside, as directed by your healthcare provider.

Step-by-step usage instructions:

1. Remove the suppository from its packaging.
2. Gently insert it deep into the vagina.
3. Wash your hands thoroughly after insertion.

Avoid missing doses, and if a dose is missed, do not double the next one. Instead, continue with the regular schedule.

Are there any precautions to take when using Metronidazole?

Yes, there are a few important precautions to keep in mind when using metronidazole:

• Alcohol consumption: Avoid drinking alcohol during the treatment and for at least 48 hours after completing the course. Combining alcohol with metronidazole may lead to severe nausea, vomiting, and other reactions.
• Treatment of sexual partners: If you are being treated for trichomoniasis, it is recommended that your sexual partner(s) also undergo treatment, even if they do not have symptoms, to prevent reinfection.
• Pregnancy and breastfeeding: Metronidazole should not be used during the first trimester of pregnancy. In the second and third trimesters, its use should only be considered if absolutely necessary, under close medical supervision. Avoid use while breastfeeding.

Can Metronidazole interact with other medications?

Yes, metronidazole can interact with certain medications. Some notable interactions include:

• Blood thinners: Metronidazole can increase the effects of blood-thinning medications, leading to an increased risk of bleeding.
• Disulfiram: Concurrent use can cause severe mental side effects like confusion and psychosis.
• Lithium: Metronidazole may raise lithium levels in the blood, potentially leading to toxicity. Always inform your healthcare provider about any other medications or supplements you are taking before starting metronidazole.

What are the possible side effects of Metronidazole?

Like any medication, metronidazole vaginal suppositories may cause side effects, although not everyone experiences them. Common side effects include:

• Vaginal itching or irritation
• Nausea or abdominal discomfort
• Headaches or dizziness
• Allergic reactions, such as rash or swelling
• Development of a yeast infection (candidiasis)

If any severe reactions occur, such as intense itching, swelling, or difficulty breathing, seek immediate medical attention.

How should I store Metronidazole vaginal suppositories?

To ensure the medication remains effective, store the suppositories in a dry place away from light. Keep them at a temperature not exceeding 25°C (77°F).

Avoid freezing the medication.

Always store it out of reach of children and check the expiration date before use.

Do not use the medication after its expiration date.