Loraktiv 10 mg (10 tablets)

  • $4.90
Sku: 10142b461769
Ingredient: Loratadine
The instruction for medical use





of LORAKTIV medicine



the Trade name

of Loraktiv



the International unlicensed





name Loratadin Lekarstvennaya a form

of the Tablet, 10 mg



Structure

One tablet contains

active agent - loratadin 10 mg,

excipients: calcium hydrophosphate, starch sodium glycollate, starch corn, starch corn (in the form of paste), the talc purified magnesium stearate.



Description

of the Tablet of an oval form, biconvex, white color.



Pharmacotherapeutic group

Antihistaminic drugs of systemic action others.

The code of automatic telephone exchange R06AX13



the Pharmacological



Pharmacokinetics Loratadin properties is quickly soaked up from digestive tract after intake, reaching peak concentration in plasma approximately in 1 hour. At reception with food the bioavailability of drug increases, time of achievement of peak concentration in plasma increases. Loratadin is exposed to extensive metabolism. The main metabolite, dezkarboetoksiloratadin, possesses expressed H1-gistaminoblokiruyushchim action. Elimination half-life of Loratadin and a dezkarboetoksiloratadin makes 12 hours and 18 hours, respectively. Loratadin contacts proteins of plasma, approximately for 98%, dezkarboetoksiloratadin to a lesser extent. Loratadin and his metabolites are defined in breast milk, but do not get through GEB, there are also no data which are authentically confirming its penetration through a placenta. Loratadin and his metabolites are removed with urine and a stake.

The pharmacodynamics

of Loraktiv - a blocker histamine H1 receptors is tricyclic antihistaminic drug of long action with selective antagonistic influence on peripheral histamine H1 receptors. Has antiallergic, antipruritic, anti-exudative effect. Reduces permeability of capillaries, prevents edematization of fabrics.



Indications

- seasonal and year-round allergic rhinitis and its symptoms (sneezing, an itching of a mucous membrane of a nose, cold, burning and an itching of eyes)

- conjunctivitis

- acute and chronic urticaria

- an allergic pruritic dermatosis: contact allergic dermatitis, chronic eczema



the Route of administration and doses

to Adults and children is more senior than 6 years: 10 mg (1 tablet) a day.

Duration of treatment is defined individually depending on duration of clinical manifestations.



Side effects

- dryness in a mouth, nausea, vomiting, gastritis

- increased fatigue, a headache, excitability (at children)

- allergic reactions

- drowsiness

- tachycardia

- it is rare: allopecia, abnormal liver functions, spasms, anaphylactic reactions.



Contraindications

- hypersensitivity to drug components

- pregnancy, the lactation period

- children's age up to 6 years.



Medicinal interactions

of Pharmakodinamicheskoye: at a concomitant use with Loraktiv alcohol does not exponentiate effect of alcohol on central nervous system.

Pharmacokinetic: at joint appointment Loraktiva with therapeutic doses of erythromycin, Cimetidinum and ketokonazol the increase in concentration of a loratadin in blood plasma without any collateral manifestations was observed.



Special instructions

to Patients with a liver or renal failure (glomerular filtration rate less than 30 ml/min.) appoint low doses (10 mg) every other day in connection with decrease in clearance of drug.

Influence of drug on ability to control of motor transport or work with mechanisms.

Considering emergence of side effects it is necessary to be careful at administration of drug at control of motor transport or work with other mechanisms.



Overdose

Symptoms: drowsiness, tachycardia, headache.

Treatment: the supporting and symptomatic treatment. To cause vomiting, then to appoint activated carbon, gastric lavage normal saline solution. Loratadin is not brought at a hemodialysis.



Form of release and packing

Primary packing: 10 tablets in blister strip packaging.

Secondary packing: 1 blister strip packaging with the instruction for medical use in cardboard packing.





To Store storage conditions in the dry, protected from light place at a temperature not over 250C.

To store out of children's reach!





3 years

not to apply a period of storage after an expiration date.



Prescription status

According to the prescription





of Proizvoditel Pletkhiko Pharmasyyutikalz Ltd / Plethico Pharmaceuticals Ltd

the location Address:

Dharavara, Kalariya 453,001, Indore (L. S.), India

Legal address:

37/37A, Indastrial Isteyt, Polograund, Indore (L. S.), 452,015, India



the Address of the organization accepting in the territory of the Republic of Kazakhstan consumers on quality of products:

Representation in RK TOO Rezlov LTD, Karaganda, Ermekov St. 116 A, office 10.

Ph. +7 (212) 442220, fax + 7 (212) 442221.

E-mail address of rezlov_ltd@mail.ru
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